Search Results - "Reese, L"
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Management and outcomes of hidradenitis suppurativa in solid organ transplant recipients
Published in British journal of dermatology (1951) (18-08-2024)“…This case series includes patients with hidradenitis suppurativa (HS) who underwent solid organ transplant with subsequent transplant-related…”
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A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle
Published in Science (American Association for the Advancement of Science) (15-01-2016)“…Muscle contraction depends on release of Ca²⁺ from the sarcoplasmic reticulum (SR) and reuptake by the Ca²⁺ adenosine triphosphatase SERCA. We discovered a…”
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Toxoplasma Rhoptry Protein 16 (ROP16) Subverts Host Function by Direct Tyrosine Phosphorylation of STAT6
Published in The Journal of biological chemistry (10-09-2010)“…The obligate intracellular parasite, Toxoplasma gondii, modulates host immunity in a variety of highly specific ways. Previous work revealed a polymorphic,…”
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Not your Mother's MAPKs: Apicomplexan MAPK function in daughter cell budding
Published in PLoS pathogens (01-10-2022)“…Reversible phosphorylation by protein kinases is one of the core mechanisms by which biological signals are propagated and processed. Mitogen-activated protein…”
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Cryo-tomography reveals rigid-body motion and organization of apicomplexan invasion machinery
Published in Nature communications (30-03-2023)“…The apical complex is a specialized collection of cytoskeletal and secretory machinery in apicomplexan parasites, which include the pathogens that cause…”
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Exploring the role of extracellular matrix proteins to develop biomarkers of plaque vulnerability and outcome
Published in Journal of internal medicine (01-05-2020)“…Cardiovascular disease (CVD) is the most common cause of death in industrialized countries. One underlying cause is atherosclerosis, which is a systemic…”
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The Toxoplasma Pseudokinase ROP5 Is an Allosteric Inhibitor of the Immunity-related GTPases
Published in The Journal of biological chemistry (03-10-2014)“…The Red Queen hypothesis proposes that there is an evolutionary arms race between host and pathogen. One possible example of such a phenomenon could be the…”
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Increasing Temperature and Relative Humidity Accelerates Inactivation of SARS-CoV-2 on Surfaces
Published in mSphere (01-07-2020)“…Coronavirus disease 2019 (COVID-19) was first identified in China in late 2019 and is caused by newly identified severe acute respiratory syndrome coronavirus…”
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Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence
Published in Proceedings of the National Academy of Sciences - PNAS (07-06-2011)“…Toxoplasma gondii, an obligate intracellular parasite of the phylum Apicomplexa, has the unusual ability to infect virtually any warm-blooded animal. It is an…”
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The impact of childhood psoriasis on the quality of life of parents and caregivers
Published in Pediatric dermatology (01-09-2023)“…We used the Psoriasis Caregiver Impact Scale to explore the quality of life (QoL) of parents/caregivers of children with psoriasis. We found that the QoL of…”
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Spontaneous neurotransmission signals through store-driven Ca2+ transients to maintain synaptic homeostasis
Published in eLife (24-07-2015)“…Spontaneous glutamate release-driven NMDA receptor activity exerts a strong influence on synaptic homeostasis. However, the properties of Ca2+ signals that…”
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Single synapse evaluation of the postsynaptic NMDA receptors targeted by evoked and spontaneous neurotransmission
Published in eLife (24-11-2016)“…Recent studies indicate that within individual synapses spontaneous and evoked release processes are segregated and regulated independently. In the…”
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Bleomycin-Induced Flagellate Dermatitis
Published in Mayo Clinic proceedings (01-02-2019)Get full text
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Assessment of inner and outer retinal layer metrics on the Cirrus HD-OCT Platform in normal eyes
Published in PloS one (04-10-2018)“…Ellipsoid zone (EZ) and outer retinal integrity are strongly linked to visual prognosis, but quantitative normative data is lacking. This study evaluates the…”
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A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence
Published in The Journal of biological chemistry (19-08-2011)“…The ROP5 family is a closely related set of polymorphic pseudokinases that are critical to the ability of Toxoplasma to cause disease. Polymorphisms in ROP5…”
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A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins
Published in PLoS biology (01-07-2012)“…The ability of mice to resist infection with the protozoan parasite, Toxoplasma gondii, depends in large part on the function of members of a complex family of…”
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Metabolic Profiling of Volatile Organic Compounds (VOCs) Emitted by the Pathogens Francisella tularensis and Bacillus anthracis in Liquid Culture
Published in Scientific reports (09-06-2020)“…We conducted comprehensive (untargeted) metabolic profiling of volatile organic compounds (VOCs) emitted in culture by bacterial taxa Francisella tularensis…”
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Analysis of retinal alterations utilizing intraoperative OCT following surgical interventions with novel ILM forceps in the DISCOVER study
Published in Scientific reports (23-07-2024)“…This study aimed to assess retinal alterations following membrane peeling procedures using novel ILM Forceps with laser ablated surface with the help of…”
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A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties
Published in Biochemical journal (15-01-2014)“…Protein kinase-like domains that lack conserved residues known to catalyse phosphoryl transfer, termed pseudokinases, have emerged as important signalling…”
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