Search Results - "Reese, Fairlie"
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L-GIREMI uncovers RNA editing sites in long-read RNA-seq
Published in Genome Biology (20-07-2023)“…Although long-read RNA-seq is increasingly applied to characterize full-length transcripts it can also enable detection of nucleotide variants, such as genetic…”
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Journal Article -
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Mapping and modeling the genomic basis of differential RNA isoform expression at single-cell resolution with LR-Split-seq
Published in Genome Biology (07-10-2021)“…The rise in throughput and quality of long-read sequencing should allow unambiguous identification of full-length transcript isoforms. However, its application…”
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Journal Article -
3
Long-Term Patterns of Noise From Underwater Explosions and Their Relation to Fisheries in Southern California
Published in Frontiers in Marine Science (23-12-2021)“…Acoustic deterrents can reduce marine mammal interactions with fisheries and aquacultures, but they contribute to an increasing level of underwater noise. In…”
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Journal Article -
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Swan: a library for the analysis and visualization of long-read transcriptomes
Published in Bioinformatics (09-06-2021)“…Abstract Motivation Long-read RNA-sequencing technologies such as PacBio and Oxford Nanopore have discovered an explosion of new transcript isoforms that are…”
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Journal Article -
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hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data
Published in Cell reports methods (26-06-2023)“…Biological systems are immensely complex, organized into a multi-scale hierarchy of functional units based on tightly regulated interactions between distinct…”
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Journal Article -
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Characterizing Transcript Diversity Using Long-Read RNA Sequencing
Published 01-01-2023“…Alternative transcripts arise from the same gene via alternative TSS usage, splicing, and polyA site choice. Such transcripts can give rise to functional…”
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Dissertation -
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Exon size and sequence conservation improves identification of splice-altering nucleotides
Published in RNA (Cambridge) (01-12-2019)“…Pre-mRNA splicing is regulated through multiple -acting splicing factors. These regulators interact with the pre-mRNA at intronic and exonic positions. Given…”
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Journal Article -
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Integration of high-resolution promoter profiling assays reveals novel, cell type-specific transcription start sites across 115 human cell and tissue types
Published in Genome research (01-02-2022)“…Accurate transcription start site (TSS) annotations are essential for understanding transcriptional regulation and its role in human disease. Gene collections…”
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Journal Article -
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Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice
Published in Cell reports (Cambridge) (26-03-2024)“…Drugs of abuse can persistently change the reward circuit in ways that contribute to relapse behavior, partly via mechanisms that regulate chromatin structure…”
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Journal Article