Search Results - "Reese, Austin L"
-
1
A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle
Published in Science (American Association for the Advancement of Science) (15-01-2016)“…Muscle contraction depends on release of Ca²⁺ from the sarcoplasmic reticulum (SR) and reuptake by the Ca²⁺ adenosine triphosphatase SERCA. We discovered a…”
Get full text
Journal Article -
2
Spontaneous neurotransmission signals through store-driven Ca2+ transients to maintain synaptic homeostasis
Published in eLife (24-07-2015)“…Spontaneous glutamate release-driven NMDA receptor activity exerts a strong influence on synaptic homeostasis. However, the properties of Ca2+ signals that…”
Get full text
Journal Article -
3
Single synapse evaluation of the postsynaptic NMDA receptors targeted by evoked and spontaneous neurotransmission
Published in eLife (24-11-2016)“…Recent studies indicate that within individual synapses spontaneous and evoked release processes are segregated and regulated independently. In the…”
Get full text
Journal Article -
4
Reelin Mobilizes a VAMP7-Dependent Synaptic Vesicle Pool and Selectively Augments Spontaneous Neurotransmission
Published in Neuron (Cambridge, Mass.) (20-11-2013)“…Reelin is a glycoprotein that is critical for proper layering of neocortex during development as well as dynamic regulation of glutamatergic postsynaptic…”
Get full text
Journal Article -
5
A positively tuned voltage indicator for extended electrical recordings in the brain
Published in Nature methods (01-07-2023)“…Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals in the brain, providing subthreshold sensitivity and temporal…”
Get full text
Journal Article -
6
An Intrinsic Transcriptional Program Underlying Synaptic Scaling during Activity Suppression
Published in Cell reports (Cambridge) (07-02-2017)“…Homeostatic scaling allows neurons to maintain stable activity patterns by globally altering their synaptic strength in response to changing activity levels…”
Get full text
Journal Article -
7
Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel
Published in Proceedings of the National Academy of Sciences - PNAS (22-12-2020)“…CLC-2 is a voltage-gated chloride channel that is widely expressed in mammalian tissues. In the central nervous system, CLC-2 appears in neurons and glia…”
Get full text
Journal Article -
8
Abstract 339: DWORF: a Novel Cardiac Micropeptide That Enhances SERCA Activity and Cardiomyocyte Contractility
Published in Circulation research (17-07-2015)“…Abstract only Background: Our lab has discovered a novel conserved micropeptide of 34 amino acids encoded by a muscle-specific RNA that was previously…”
Get full text
Journal Article -
9
Abstract 189: DWORF: Discovery and Characterization of a Cardiac Micropeptide Encoded in a Putative Long Noncoding RNA
Published in Circulation research (17-07-2015)“…Abstract only Background: Mammalian transcriptomes contain thousands of potential open reading frames (ORFs) with fewer than fifty codons. Most of these ORFs…”
Get full text
Journal Article -
10
Spontaneous neurotransmission signals through store-driven Ca(2+) transients to maintain synaptic homeostasis
Published in eLife (24-07-2015)“…Spontaneous glutamate release-driven NMDA receptor activity exerts a strong influence on synaptic homeostasis. However, the properties of Ca(2+) signals that…”
Get full text
Journal Article