Search Results - "Reen, Virinder"

Clearing stressed cells by Reen, Virinder, Gil, Jesús

“…Cell cycle arrest produces a p21-dependent secretome that initiates immunosurveillance of premalignant cells…”
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Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression by Born, Emmanuelle, Lipskaia, Larissa, Breau, Marielle, Houssaini, Amal, Beaulieu, Delphine, Marcos, Elisabeth, Pierre, Remi, Do Cruzeiro, Marcio, Lefevre, Marine, Derumeaux, Genevieve, Bulavin, Dmitry V., Delcroix, Marion, Quarck, Rozenn, Reen, Virinder, Gil, Jesus, Bernard, David, Flaman, Jean-Michel, Adnot, Serge, Abid, Shariq

“…Senescent cells (SCs) are involved in proliferative disorders, but their role in pulmonary hypertension remains undefined. We investigated SCs in patients with…”
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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer by Haston, Scott, Gonzalez-Gualda, Estela, Morsli, Samir, Ge, Jianfeng, Reen, Virinder, Calderwood, Alexander, Moutsopoulos, Ilias, Panousopoulos, Leonidas, Deletic, Polina, Carreno, Gabriela, Guiho, Romain, Manshaei, Saba, Gonzalez-Meljem, Jose Mario, Lim, Hui Yuan, Simpson, Daniel J., Birch, Jodie, Pallikonda, Husayn A., Chandra, Tamir, Macias, David, Doherty, Gary J., Rassl, Doris M., Rintoul, Robert C., Signore, Massimo, Mohorianu, Irina, Akbar, Arne N., Gil, Jesús, Muñoz-Espín, Daniel, Martinez-Barbera, Juan Pedro

“…The accumulation of senescent cells in the tumor microenvironment can drive tumorigenesis in a paracrine manner through the senescence-associated secretory…”
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Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression by Born, Emmanuelle, Lipskaia, Larissa, Breau, Marielle, Houssaini, Amal, Beaulieu, Delphine Paulette, Marcos, Elizabeth, Pierre, Remi, Do Cruzeiro, Marcio, Lefevre, Marine, Derumeaux, Genevieve, Bulavin, Dmitry V., Delcroix, Marion, Quarck, Rozenn, Reen, Virinder, Gil, Jesus, Bernard, David, Flaman, Jean-Michel, Adnot, Serge, Abid, Shariq

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RF13 | PMON143 BRF1-Mediated Paracrine Signalling by a Subset of SOX2-Expressing Stem Cells is Required for Normal Development of the Stem Cell Compartment and Terminal Differentiation of Pituitary Committed Progenitors by Manshaei, Saba, Willis, Thea L, Reen, Virinder, Pallikonda, Husayn, Birch, Jodie, Withers, Dominic J, Gil, Jesus, Andoniadou, Cynthia L, Martinez-Barbera, Juan Pedro

“…Abstract Introduction Hormone-producing pituitary cell lineages are derived from a population of embryonic precursors expressing SOX2. These cells maintain…”
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Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome by Gallage, Suchira, Irvine, Elaine E., Barragan Avila, Jose Efren, Reen, Virinder, Pedroni, Silvia M. A., Duran, Imanol, Ranvir, Vikas, Khadayate, Sanjay, Pombo, Joaquim, Brookes, Sharon, Heide, Danijela, Dharmalingham, Gopuraja, Choudhury, Agharul I., Singh, Indrabahadur, Herranz, Nicolás, Vernia, Santiago, Heikenwalder, Mathias, Gil, Jesús, Withers, Dominic J.

“…Inhibition of S6 kinase 1 (S6K1) extends lifespan and improves healthspan in mice, but the underlying mechanisms are unclear. Cellular senescence is a stable…”
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Abstract 443: The anion channel GPHR/GPR89 regulates protein-folding homeostasis by regulating the IRE1α pathway in breast cancer by Ferro, Riccardo, Marra, Pierfrancesco, Pereira, Ana Mendes, Reen, Virinder, Prince, Cynthia, Mathew, Sumi, Facchetti, Alessandra, Ghongane-Salpe, Priyanka, Kareemaghay, Sedigeh, Gazinska, Patrycja, Robertson, David, Noor, Farzana, Maristany, Fara Braso', Weekes, Daniel, Krastev, Dragomir, Tenev, Tencho, Mirza, Hasan, Patel, Nirmesh, Grigoriadis, Anita, Tutt, Andrew

“…Abstract In order to identify novel tumor drivers and gene addictions in breast cancer we have recently completed an integrated in silico/in vitro analysis of…”
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