Search Results - "Reen, Rashmeet"

Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D by Byfield, Fitzroy J, Reen, Rashmeet K, Shentu, Tzu-Pin, Levitan, Irena, Gooch, Keith J

“…Abstract There is a growing appreciation of the profound effects that passive mechanical properties, especially the stiffness of the local environment, can…”
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Arterial levels of oxygen stimulate intimal hyperplasia in human saphenous veins via a ROS-dependent mechanism by Joddar, Binata, Firstenberg, Michael S, Reen, Rashmeet K, Varadharaj, Saradhadevi, Khan, Mahmood, Childers, Rachel C, Zweier, Jay L, Gooch, Keith J

“…Saphenous veins used as arterial grafts are exposed to arterial levels of oxygen partial pressure (pO2), which are much greater than what they experience in…”
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High throughput assembly of spatially controlled 3D cell clusters on a micro/nanoplatform by Gallego-Perez, Daniel, Higuita-Castro, Natalia, Sharma, Sadhana, Reen, Rashmeet K, Palmer, Andre F, Gooch, Keith J, Lee, L James, Lannutti, John J, Hansford, Derek J

“…Guided assembly of microscale tissue subunits (i.e. 3D cell clusters/aggregates) has found applications in cell therapy/tissue engineering, cell and…”
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The mouse and human Ah receptor differ in recognition of LXXLL motifs by Flaveny, Colin, Reen, Rashmeet K., Kusnadi, Ann, Perdew, Gary H.

“…The aryl hydrocarbon receptor (AhR) is a ligand inducible transcription factor that exhibits interspecies differences, with the human and mouse AhR C-terminal…”
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Carcinogen-altered genes in rat esophagus positively modulated to normal levels of expression by both black raspberries and phenylethyl isothiocyanate by Stoner, Gary D, Dombkowski, Alan A, Reen, Rashmeet K, Cukovic, Daniela, Salagrama, Sridevi, Wang, Li-Shu, Lechner, John F

“…Our recent study identified 2,261 dysregulated genes in the esophagi of rats that received a 1-week exposure to the carcinogen N-nitrosomethylbenzylamine…”
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Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway by Joddar, Binata, Reen, Rashmeet K., Firstenberg, Michael S., Varadharaj, Saradhadevi, McCord, Joe M., Zweier, Jay L., Gooch, Keith J.

“…Human saphenous veins (HSVs) are widely used for bypass grafts despite their relatively low long-term patency. To evaluate the role of reactive oxygen species…”
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Vacuum-Assisted Cell Seeding in a Microwell Cell Culture System by Ferrell, Nicholas, Gallego-Perez, Daniel, Higuita-Castro, Natalia, Butler, Randall T, Reen, Rashmeet K, Gooch, Keith J, Hansford, Derek J

“…We present a simple method to actively pattern individual cells and groups of cells in a polymer-based microdevice using vacuum-assisted cell seeding. Soft…”
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Micro/nanoscale technologies for the development of hormone-expressing islet-like cell clusters by Gallego-Perez, Daniel, Higuita-Castro, Natalia, Reen, Rashmeet K., Palacio-Ochoa, Marcela, Sharma, Sadhana, Lee, L. James, Lannutti, John J., Hansford, Derek J., Gooch, Keith J.

“…Insulin-expressing islet-like cell clusters derived from precursor cells have significant potential in the treatment of type-I diabetes. Given that cluster…”
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Modulation of N-nitrosomethylbenzylamine metabolism by black raspberries in the esophagus and liver of Fischer 344 rats by Reen, R.K, Nines, R, Stoner, G.D

“…Dietary freeze-dried black raspberries (BRBs) inhibit N-nitrosomethylbenzylamine (NMBA)-induced tumorigenesis in the Fischer 344 rat esophagus. To determine…”
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Effects of a Black Raspberry Diet on Gene Expression in the Rat Esophagus by Lechner, John F, Reen, Rashmeet K, Dombkowski, Alan A, Cukovic, Daniela, Salagrama, Sridevi, Wang, Li-Shu, Stoner, Gary D

“…A diet containing 5% freeze-dried black raspberries (BRB) markedly inhibits esophageal cancer in rats treated with the carcinogen, N-Nitrosomethylbenzylamine…”
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Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus by Reen, Rashmeet K, Dombkowski, Alan A, Kresty, Laura A, Cukovic, Daniela, Mele, Jennifer M, Salagrama, Sridevi, Nines, Ronald, Stoner, Gary D

“…There is little information on early molecular events in the development of N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis and of the…”
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Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity by Murray, Iain A., Reen, Rashmeet K., Leathery, Nathan, Ramadoss, Preeti, Bonati, Laura, Gonzalez, Frank J., Peters, Jeffrey M., Perdew, Gary H.

“…The aryl hydrocarbon receptor (AhR) mediates the biological activity of 2,3,7,8-tetrachlorodibenzo- p-dioxin. Whether the AhR can mediate enhanced…”
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The subdomains of the transactivation domain of the aryl hydrocarbon receptor (AhR) inhibit AhR and estrogen receptor transcriptional activity by Reen, Rashmeet K, Cadwallader, Adam, Perdew, Gary H

“…2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) activates the aryl hydrocarbon receptor (AhR) to mediate transcriptional activity of dioxin-responsive genes. The…”
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Arterial pO2 stimulates intimal hyperplasia and serum stimulates inward eutrophic remodeling in porcine saphenous veins cultured ex vivo by Joddar, Binata, Shaffer, Rebecca J. G., Reen, Rashmeet K., Gooch, Keith J.

“…Ex vivo culture of arteries and veins is an established tool for investigating mechanically induced remodeling. Porcine saphenous veins (PSV) cultured ex vivo…”
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Malnutrition sequela on the drug metabolizing enzymes in male Holtzman rats by Reen, Rashmeet K, Melo, Gustavo E.B.A, Moraes-Santos, T

“…The effect of food restriction on the specific activities of the drug metabolizing enzymes (DME) system was studied in Holtzman male rats by comparing DME…”
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Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine by Reen, R K, Jamwal, D S, Taneja, S C, Koul, J L, Dubey, R K, Wiebel, F J, Singh, J

“…The effects of piperine, a major ingredient of black pepper, on UDP-glucose dehydrogenase (UDP-GDH) and glucuronidation potentials of rat and guinea pig liver…”
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The Q-rich Subdomain of the Human AhReceptor Transactivation Domain Is Required for Dioxin-mediated Transcriptional Activity by Kumar, Mohan B., Ramadoss, Preeti, Reen, Rashmeet K., Vanden Heuvel, John P., Perdew, Gary H.

“…The aryl hydrocarbon receptor (AhR), a basic helix-loop-helix/Per-Arnt-Sim transcription factor, mediates many of the toxic and biological effects of the…”
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Abstract 5858: Role of Oxygen Tension and Oxidative Stress in Human Saphenous Vein Remodeling by Joddar, Binata, Reen, Rashmeet K, Firstenberg, Michael, Gooch, Keith J

“…Abstract only Vessels cultured ex vivo maintain viability and vasoactivity for weeks and can remodel in response to mechanical cues. When cultured in the…”
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Arterial pO sub(2) stimulates intimal hyperplasia and serum stimulates inward eutrophic remodeling in porcine saphenous veins cultured ex vivo by Joddar, Binata, Shaffer, Rebecca JG, Reen, Rashmeet K, Gooch, Keith J

“…Ex vivo culture of arteries and veins is an established tool for investigating mechanically induced remodeling. Porcine saphenous veins (PSV) cultured ex vivo…”
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Pancreatic Epithelial Cells Form Islet-Like Clusters in the Absence of Directed Migration by Holfinger, Steven J., Reinhardt, James W., Reen, Rashmeet, Schultz, Kevin M., Passino, Kevin M., Ackerman, William E., Kniss, Douglas A., Sander, Leonard M., Gallego-Perez, Daniel, Gooch, Keith J.

“…The endocrine differentiation of pancreatic ductal epithelial cells is dependent upon their transition from a two-dimensional monolayer to three-dimensional…”
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