Search Results - "Reeders, Stephen T."

Identification of mutations in the α3(IV) and α4(IV) collagen genes in autosomal recessive Alport syndrome by Mochizuki, Toshio, Chan, Belinda, Smeets, Hubert J, Lemmink, Henny H, Antignac, Corinne, Mariyama, Mariko, Gubler, Marie-Claire, Schröder, Cornelis H, Verellen-Dumoulin, Christine, Pirson, Yves, Reeders, Stephen T

Get full text

The Diagnosis and Prognosis of Autosomal Dominant Polycystic Kidney Disease by Parfrey, Patrick S, Bear, John C, Morgan, Janet, Cramer, Benvon C, McManamon, Patrick J, Gault, Mathew H, Churchill, David N, Singh, Manoj, Hewitt, Richard, Somlo, Stefan, Reeders, Stephen T

“…AUTOSOMAL dominant polycystic kidney disease is responsible for 6 to 9 percent of cases of end-stage renal disease in North America 1 ' 2 and Europe. 3 About 1…”
Get full text

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions by Hediger, Matthias A, Zhou, Jing, Chen, Xing-Zhen, Vassilev, Peter M, Basora, Nuria, Peng, Ji-Bin, Nomura, Hideki, Segal, Yoav, Brown, Edward M, Reeders, Stephen T

“…Polycystic kidney diseases are genetic disorders in which the renal parenchyma is progressively replaced by fluid-filled cysts. Two members of the polycystin…”
Get full text

Identification of PKDL, a Novel Polycystic Kidney Disease 2-Like Gene Whose Murine Homologue Is Deleted in Mice with Kidney and Retinal Defects by Nomura, Hideki, Turco, Alberto E., Pei, York, Kalaydjieva, Luba, Schiavello, Tina, Weremowicz, Stanislawa, Ji, Weizhen, Morton, Cynthia C., Meisler, Miriam, Reeders, Stephen T., Zhou, Jing

“…Polycystin-1 and polycystin-2 are the products of PKD1 and PKD2, genes that are mutated in most cases of autosomal dominant polycystic kidney disease…”
Get full text

Deletion of the Paired α5(IV) and α6(IV) Collagen Genes in Inherited Smooth Muscle Tumors by Zhou, Jing, Mochizuki, Toshio, Smeets, Hubert, Antignac, Corinne, Laurila, Pekka, de Paepe, Anne, Tryggvason, Karl, Reeders, Stephen T.

“…The gene encoding α6(IV) collagen, COL4A6, was identified on the human X chromosome in a head-to-head arrangement and within 452 base pairs of the α5(IV)…”
Get full text

Multilocus polycystic disease by Reeders, Stephen T

Get full text

Molecular characteristics of the Goodpasture autoantigen by Hudson, Billy G., Kalluri, Raghuram, Gunwar, Sripad, Noelken, Milton E., Mariyama, Mariko, Reeders, Stephen T.

“…Molecular characteristics of the Goodpasture autoantigen. Goodpasture syndrome is an autoimmune disease causing rapidly progressive glomerulonephritis and…”
Get full text

Type IV collagen: structure, gene organization, and role in human diseases. Molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis by Hudson, B G, Reeders, S T, Tryggvason, K

“…Basement membranes (BMs) are thin sheetlike extracellular structures that compartmentalize tissues. They provide substrata for organ cells and important…”
Get full text

Identification and localization of polycystin, the PKD1 gene product by Geng, L, Segal, Y, Peissel, B, Deng, N, Pei, Y, Carone, F, Rennke, H G, Glücksmann-Kuis, A M, Schneider, M C, Ericsson, M, Reeders, S T, Zhou, J

“…Polycystin, the product of autosomal dominant polycystic kidney disease (ADPKD) 1 gene (PKD1) is the cardinal member of a novel class of proteins. As a first…”
Get full text

Complete primary structure of the sixth chain of human basement membrane collagen, α6(IV) : isolation of the cDNAS for α6(IV) and comparison with five other type IV collagen chains by JING ZHOU, MING DING, ZHIHUI ZHAO, REEDERS, S. T

Get full text

Distribution and developmentally regulated expression of murine polycystin by Geng, L, Segal, Y, Pavlova, A, Barros, E J, Löhning, C, Lu, W, Nigam, S K, Frischauf, A M, Reeders, S T, Zhou, J

“…PKD1, the gene that is mutated in approximately 85% of autosomal dominant polycystic kidney disease (ADPKD) cases in humans, has recently been identified (Eur…”
Get full text

Sequence and localization of a partial cDNA encoding the human α3 chain of type IV collagen by MORRISON, K. E, MARIYAMA, M, YANG-FENG, T. L, REEDERS, S. T

Get full text

The alpha chains of type IV collagen by Zhou, J, Reeders, S T

Get more information

Goodpasture syndrome : localization of the epitope for the autoantibodies to the carboxyl-terminal region of the α3(IV) chain of basement membrane collagen by KALLURI, R, GUNWAR, S, REEDERS, S. T, MORRISON, K. C, MARIYAMA, M, EBNER, K. E, NOELKEN, M. E, HUDSON, B. G

Get full text

Use of the polymerase chain reaction to clone and sequence a cDNA encoding the bovine α3 chain of type IV collagen by MORRISON, K. E, GERMINO, G. G, REEDERS, S. T

Get full text

A new human gene located in the PKD1 region of chromosome 16 is a functional homologue to ERV1 of yeast by LISOWSKY, T, WEINSTAT-SASLOW, D. L, BARTON, N, REEDERS, S. T, SCHNEIDER, M. C

“…A new human gene has been identified on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1) by analysis of a genomic cosmid…”
Get full text

Molecular genetics of hereditary nephritis by Reeders, Stephen T.

Get full text

Specificity of Goodpasture autoantibodies for the recombinant noncollagenous domains of human type IV collagen by NEILSON, E. G, KALLURI, R, SUN, M. J, SRIPAD GUNWAR, DANOFF, T, MARIYAMA, M, MYERS, J. C, REEDERS, S. T, HUDSON, B. G

“…Type IV collagen has recently emerged as a family composed of five known chains (alpha 1-alpha 5), each of which contains a carboxyl-terminal noncollagenous…”
Get full text

A kindred exhibiting cosegregation of an overlap connective tissue disorder and the chromosome 16 linked form of autosomal dominant polycystic kidney disease by Somlo, S, Rutecki, G, Giuffra, L A, Reeders, S T, Cugino, A, Whittier, F C

“…Autosomal dominant polycystic kidney disease (ADPKD) is a disorder of adult onset manifested by bilaterally enlarged cystic kidneys frequently associated with…”
Get full text

Structure of the Human Type IV CollagenCOL4A6Gene, Which Is Mutated in Alport Syndrome-Associated Leiomyomatosis by Zhang, Xu, Zhou, Jing, Reeders, Stephen T., Tryggvason, Karl

“…Basement membrane (type IV) collagen, a subfamily of the collagen protein family, is encoded by six distinct genes in mammals. Three of those,COL4A3,…”
Get full text