Search Results - "Reed, Rolanda L."

Structure-based design, synthesis, and biological evaluation of novel 1,4-diazepines as HDM2 antagonists by Raboisson, Pierre, Marugán, Juan José, Schubert, Carsten, Koblish, Holly K., Lu, Tianbao, Zhao, Shuyuan, Player, Mark R., Maroney, Anna C., Reed, Rolanda L., Huebert, Norman D., Lattanze, Jennifer, Parks, Daniel J., Cummings, Maxwell D.

“…Novel 1,4-diazepine-2,5-diones that act as antagonists of the HDM2–p53 interaction are reported. Crystallographic analysis of ligands bound to HDM2 suggested…”
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Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors by Qiao, Lei, Baumann, Christian A., Crysler, Carl S., Ninan, Nisha S., Abad, Marta C., Spurlino, John C., DesJarlais, Renee L., Kervinen, Jukka, Neeper, Mike P., Bayoumy, Shariff S., Williams, Robyn, Deckman, Ingrid C., Dasgupta, Malini, Reed, Rolanda L., Huebert, Norman D., Tomczuk, Bruce E., Moriarty, Kevin J.

“…The discovery, SAR, and X-ray crystal structure of novel biarylaminoacyl-( S)-2-cyano-pyrrolidines and biarylaminoacylthiazolidines as potent inhibitors of…”
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