Search Results - "Reed, Kevin B."

A tripartite microbial co-culture system for de novo biosynthesis of diverse plant phenylpropanoids by Brooks, Sierra M., Marsan, Celeste, Reed, Kevin B., Yuan, Shuo-Fu, Nguyen, Dustin-Dat, Trivedi, Adit, Altin-Yavuzarslan, Gokce, Ballinger, Nathan, Nelson, Alshakim, Alper, Hal S.

“…Plant-derived phenylpropanoids, in particular phenylpropenes, have diverse industrial applications ranging from flavors and fragrances to polymers and…”
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A modular and synthetic biosynthesis platform for de novo production of diverse halogenated tryptophan-derived molecules by Reed, Kevin B., Brooks, Sierra M., Wells, Jordan, Blake, Kristin J., Zhao, Minye, Placido, Kira, d’Oelsnitz, Simon, Trivedi, Adit, Gadhiyar, Shruti, Alper, Hal S.

“…Halogen-containing molecules are ubiquitous in modern society and present unique chemical possibilities. As a whole, de novo fermentation and synthetic pathway…”
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Author Correction: A modular and synthetic biosynthesis platform for de novo production of diverse halogenated tryptophan-derived molecules by Reed, Kevin B., Brooks, Sierra M., Wells, Jordan, Blake, Kristin J., Zhao, Minye, Placido, Kira, d’Oelsnitz, Simon, Trivedi, Adit, Gadhiyar, Shruti, Alper, Hal S.

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Improving ionic liquid tolerance in Saccharomyces cerevisiae through heterologous expression and directed evolution of an ILT1 homolog from Yarrowia lipolytica by Reed, Kevin B., Wagner, James M., d’Oelsnitz, Simon, Wiggers, Joshua M., Alper, Hal S.

“…Ionic liquids show promise for deconstruction of lignocellulosic biomass prior to fermentation. Yet, imidazolium ionic liquids (IILs) can be toxic to microbes…”
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Expanding beyond canonical metabolism: Interfacing alternative elements, synthetic biology, and metabolic engineering by Reed, Kevin B., Alper, Hal S.

“…Metabolic engineering offers an exquisite capacity to produce new molecules in a renewable manner. However, most industrial applications have focused on only a…”
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Evolving dual-trait EPSP synthase variants using a synthetic yeast selection system by Reed, Kevin B, Kim, Wantae, Lu, Hongyuan, Larue, Clayton T, Guo, Shirley, Brooks, Sierra M, Montez, Michael R, Wagner, James W, Zhang, Y Jessie, Alper, Hal S

“…The enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) functions in the shikimate pathway which is responsible for the production of aromatic amino…”
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Enhancing long‐term storage and stability of engineered living materials through desiccant storage and trehalose treatment by Brooks, Sierra M., Reed, Kevin B., Yuan, Shuo‐Fu, Altin‐Yavuzarslan, Gokce, Shafranek, Ryan, Nelson, Alshakim, Alper, Hal S.

“…Engineered living materials (ELMs) have broad applications for enabling on‐demand bioproduction of compounds ranging from small molecules to large proteins…”
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T7 Polymerase Expression of Guide RNAs in vivo Allows Exportable CRISPR-Cas9 Editing in Multiple Yeast Hosts by Morse, Nicholas J, Wagner, James M, Reed, Kevin B, Gopal, Madan R, Lauffer, Lars H, Alper, Hal S

“…Efficient guide RNA expression often limits CRISPR-Cas9 implementation in new hosts. To address this limitation in fungal systems, we demonstrate the utility…”
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Fluorescence-Based Screens for Engineering Enzymes Linked to Halogenated Tryptophan by Reed, Kevin B., d’Oelsnitz, Simon, Brooks, Sierra M., Wells, Jordan, Zhao, Minye, Trivedi, Adit, Eshraghi, Selina, Alper, Hal S.

“…Directed evolution is often limited by the throughput of accurate screening methods. Here we demonstrate the feasibility of utilizing a singular transcription…”
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Modular biocatalysis for polyamines by Reed, Kevin B., Alper, Hal S.

“…Polyamines are a growing class of medically and agriculturally active biomolecules that have traditionally been difficult to source. Now, a bio-based platform…”
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