Search Results - "Reed, James"

Engineering terpenoid production through transient expression in Nicotiana benthamiana by Reed, James, Osbourn, Anne

“…Terpenoids are the most structurally diverse class of plant natural products with a huge range of commercial and medical applications. Exploiting this enormous…”
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Bridging funding gaps for climate and sustainable development: Pitfalls, progress and potential of private finance by Clark, Robyn, Reed, James, Sunderland, Terry

“…In a world where natural capital is often unpriced or undervalued, thus making resource exploitation very lucrative, environmentally degrading activities will…”
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Impact of sodium-glucose cotransporter 2 inhibitors on blood pressure by Reed, James W

“…SGLT2 inhibitors are glucose-lowering agents used to treat type 2 diabetes mellitus (T2DM). These agents target the kidney to promote urinary glucose…”
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Integrated landscape approaches to managing social and environmental issues in the tropics: learning from the past to guide the future by Reed, James, Van Vianen, Josh, Deakin, Elizabeth L., Barlow, Jos, Sunderland, Terry

“…Poverty, food insecurity, climate change and biodiversity loss continue to persist as the primary environmental and social challenges faced by the global…”
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Harnessing plant biosynthesis for the development of next-generation therapeutics by Spence, Philip, Reed, James, Osbourn, Anne

“…Genomics-based predictions indicate that plants harbor the ability to make a vast array of as yet undiscovered chemistry. Recent advances open up the potential…”
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Thinking bedside at the bench: the NOD mouse model of T1DM by Reed, James C., Herold, Kevan C.

“…Successful studies in the nonobese diabetic (NOD) mouse model often do not translate to positive outcomes in human studies. This Perspectives outlines the…”
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Particulate matter containing environmentally persistent free radicals induces AhR-dependent cytokine and reactive oxygen species production in human bronchial epithelial cells by Harmon, Ashlyn C, Hebert, Valeria Y, Cormier, Stephania A, Subramanian, Balamurugan, Reed, James R, Backes, Wayne L, Dugas, Tammy R

“…Particulate matter (PM) is emitted during the combustion of fuels and wastes. PM exposure exacerbates pulmonary diseases, and the mechanism may involve…”
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The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling by Reed, James C, Preston-Hurlburt, Paula, Philbrick, William, Betancur, Gabriel, Korah, Maria, Lucas, Carrie, Herold, Kevan C

“…The receptor for advanced glycation endproducts (RAGE) is expressed in T cells after activation with antigen and is constitutively expressed in T cells from…”
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Formation and diversification of a paradigm biosynthetic gene cluster in plants by Liu, Zhenhua, Cheema, Jitender, Vigouroux, Marielle, Hill, Lionel, Reed, James, Paajanen, Pirita, Yant, Levi, Osbourn, Anne

“…Numerous examples of biosynthetic gene clusters (BGCs), including for compounds of agricultural and medicinal importance, have now been discovered in plant…”
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CYP1A1 and CYP1A2 Form Distinct Protein Complexes with NADPH-cytochrome P450 Reductase, Cytochrome b 5 , and Heme Oxygenase-1 by Connick, Patrick, Reed, James R, Backes, Wayne L

“…The cytosolic face of the endoplasmic reticulum (ER) membrane contains a variety of enzymes involved in oxidative metabolism. Among these, NADPH-cytochrome…”
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The Influence of Lipid Microdomain Heterogeneity on Protein-Protein Interactions: Proteomic Analysis of Co-Immunoprecipitated Binding Partners of P450 1A2 and P450 3A in Rat Liver Microsomes by Reed, James R, Guidry, Jessie J, Eyer, Marilyn, Backes, Wayne L

“…Liver cytochrome P450s (CYPs) of the endoplasmic reticulum (ER) are involved in the metabolism of exogenous and endogenous chemicals. The ER is not uniform,…”
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Proteomic and Bioinformatics Analysis of Membrane Lipid Domains after Brij 98 Solubilization of Uninduced and Phenobarbital-Induced Rat Liver Microsomes: Defining the Membrane Localization of the P450 Enzyme System by Reed, James R, Guidry, Jessie J, Backes, Wayne L

“…The proteomes of ordered and disordered lipid microdomains in rat liver microsomes from control and phenobarbital (PB)-treated rats were determined after…”
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Effective Fine-Structure Constant of Freestanding Graphene Measured in Graphite by Reed, James P, Uchoa, Bruno, Joe, Young Il, Gan, Yu, Casa, Diego, Fradkin, Eduardo, Abbamonte, Peter

“…Electrons in graphene behave like Dirac fermions, permitting phenomena from high-energy physics to be studied in a solid-state setting. A key question is…”
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Chest Radiology: Patterns and Differential Diagnoses by Reed, James C

“…'Chest Radiology' walks you through a logical, sequential thought process for the differential diagnoses of 23 radiologic patterns of common chest diseases,…”
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Formation of P450 · P450 complexes and their effect on P450 function by Reed, James R, Backes, Wayne L

“…Cytochromes P450 (P450) are membrane-bound enzymes that catalyze the monooxygenation of a diverse array of xenobiotic and endogenous compounds. The P450s…”
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Highly efficient coproduction of electrical power and synthesis gas from biohythane using solid oxide fuel cell technology by Panagi, Kleitos, Laycock, Christian J., Reed, James P., Guwy, Alan J.

“…[Display omitted] •Utilisation of biohythane in solid oxide fuel cells investigated for first time.•Coproduction of energy and syngas has been demonstrated…”
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A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules by Reed, James, Stephenson, Michael J., Miettinen, Karel, Brouwer, Bastiaan, Leveau, Aymeric, Brett, Paul, Goss, Rebecca J.M., Goossens, Alain, O’Connell, Maria A., Osbourn, Anne

“…Plants are an excellent source of drug leads. However availability is limited by access to source species, low abundance and recalcitrance to chemical…”
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Identification of the N-terminal residues responsible for the differential microdomain localization of CYP1A1 and CYP1A2 by Fuchs, Robert M., Reed, James R., Connick, J. Patrick, Paloncýová, Markéta, Šrejber, Martin, Čechová, Petra, Otyepka, Michal, Eyer, Marilyn K., Backes, Wayne L.

“…The endoplasmic reticulum is organized into ordered regions enriched in cholesterol and sphingomyelin, and disordered microdomains characterized by more…”
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Functional characterization of CYP1 enzymes: Complex formation, membrane localization and function by Connick, J. Patrick, Reed, James R., Cawley, George F., Saha, Aratrika, Backes, Wayne L.

“…CYP1A1, CYP1A2, and CYP1B1 have a high degree of sequence similarity, similar substrate selectivities and induction characteristics. However, experiments…”
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Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity by Brignac-Huber, Lauren M, Park, Ji Won, Reed, James R, Backes, Wayne L

“…Cytochrome P450s (P450s) comprise a superfamily of proteins that catalyze numerous monooxygenase reactions in animals, plants, and bacteria. In eukaryotic…”
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