Search Results - "Reed, E. F."

Effect of Antibodies on Endothelium by Zhang, X., Reed, E. F.

“…Patients developing posttransplant antibodies against HLA and non‐HLA antigens expressed by the endothelium of the graft undergo more frequent episodes of…”
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Comprehensive Assessment and Standardization of Solid Phase Multiplex‐Bead Arrays for the Detection of Antibodies to HLA by Reed, E. F., Rao, P., Zhang, Z., Gebel, H., Bray, R. A., Guleria, I., Lunz, J., Mohanakumar, T., Nickerson, P., Tambur, A. R., Zeevi, A., Heeger, P. S., Gjertson, D.

“…Solid phase multiplex‐bead arrays for the detection and characterization of HLA antibodies provide increased sensitivity and specificity compared to…”
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Everolimus Inhibits Anti‐HLA I Antibody‐Mediated Endothelial Cell Signaling, Migration and Proliferation More Potently Than Sirolimus by Jin, Y.‐P., Valenzuela, N. M., Ziegler, M. E., Rozengurt, E., Reed, E. F.

“…Antibody (Ab) crosslinking of HLA I molecules on the surface of endothelial cells triggers proliferative and pro‐survival intracellular signaling, which is…”
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Standardization and Cross Validation of Alloreactive IFNγ ELISPOT Assays Within the Clinical Trials in Organ Transplantation Consortium by Ashoor, I., Najafian, N., Korin, Y., Reed, E. F., Mohanakumar, T., Ikle, D., Heeger, P. S., Lin, M.

“…Emerging evidence indicates memory donor‐reactive T cells are detrimental to transplant outcome and that quantifying the frequency of IFNγ‐producing,…”
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Blockade of P‐Selectin Is Sufficient to Reduce MHC I Antibody‐Elicited Monocyte Recruitment In Vitro and In Vivo by Valenzuela, N. M., Hong, L., Shen, X.‐Da, Gao, F., Young, S. H., Rozengurt, E., Kupiec‐Weglinski, J. W., Fishbein, M. C., Reed, E. F.

“…Donor‐specific HLA antibodies significantly lower allograft survival, but as yet there are no satisfactory therapies for prevention of antibody‐mediated…”
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Dynamic Challenges Inhibiting Optimal Adoption of Kidney Paired Donation: Findings of a Consensus Conference by Melcher, M. L., Blosser, C. D., Baxter‐Lowe, L. A., Delmonico, F. L., Gentry, S. E., Leishman, R., Knoll, G. A., Leffell, M. S., Leichtman, A. B., Mast, D. A., Nickerson, P. W., Reed, E. F., Rees, M. A., Rodrigue, J. R., Segev, D. L., Serur, D., Tullius, S. G., Zavala, E. Y., Feng, S.

“…While kidney paired donation (KPD) enables the utilization of living donor kidneys from healthy and willing donors incompatible with their intended recipients,…”
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Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling by Keslar, K. S., Lin, M., Zmijewska, A. A., Sigdel, T. K., Tran, T. Q., Ma, L., Bhasin, M., Rao, P., Ding, R., Iklé, D. N., Mannon, R. B., Sarwal, M. M., Strom, T. B., Reed, E. F., Heeger, P. S., Suthanthiran, M., Fairchild, R. L.

“…Gene expression profiling of transplant recipient blood and urine can potentially be used to monitor graft function, but the multitude of protocols in use make…”
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Precision Diagnostics in Transplantation: From Bench to Bedside by Mengel, M., Campbell, P., Gebel, H., Randhawa, P., Rodriguez, E. R., Colvin, R., Conway, J., Hachem, R., Halloran, P. F., Keshavjee, S., Nickerson, P., Murphey, C., O'Leary, J., Reeve, J., Tinckam, K., Reed, E. F.

“…The Canadian and American Societies of Transplantation held a symposium on February 22, 2012 in Quebec City focused on discovery, validation and translation of…”
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Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses by Hagan, Thomas, Gerritsen, Bram, Tomalin, Lewis E., Fourati, Slim, Mulè, Matthew P., Chawla, Daniel G., Rychkov, Dmitri, Henrich, Evan, Miller, Helen E. R., Diray-Arce, Joann, Dunn, Patrick, Lee, Audrey, Levy, Ofer, Gottardo, Raphael, Sarwal, Minne M., Tsang, John S., Suárez-Fariñas, Mayte, Sékaly, Rafick-Pierre, Kleinstein, Steven H., Pulendran, Bali

“…Systems vaccinology has defined molecular signatures and mechanisms of immunity to vaccination. However, comparative analysis of immunity to different vaccines…”
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Increased T cell immunosenescence and accelerated maturation phenotypes in older kidney transplant recipients by Schaenman, J.M., Rossetti, M., Sidwell, T., Groysberg, V., Sunga, G., Korin, Y., Liang, E., Zhou, X., Abdalla, B., Lum, E., Bunnapradist, S., Pham, T., Danovitch, G., Reed, E.F.

“…Older kidney transplant recipients experience increased rates of infection and death, and less rejection, compared with younger patients. However, little is…”
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A novel HLA-C null allele, HLA-C08:121N by Zhang, X., Reed, E. F.

“…HLA‐C*08:121N results from two‐nucleotide loss compared with its closest allele HLA‐C*08:01:01…”
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Identification of an HLA‐A null allele, HLA‐A33:129N by Yin, Y., Takemura, P., Reed, E. F., Zhang, Q.

“…HLA‐A*33:129N has a single nucleotide insertion compared with its closest allele HLA‐A*33:01:01 at codon 186…”
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Standardization and Cross Validation of Alloreactive IFN[gamma] ELISPOT Assays Within the Clinical Trials in Organ Transplantation Consortium by Ashoor, I, Najafian, N, Korin, Y, Reed, E. F, Mohanakumar, T, Ikle, D, Heeger, P. S, Lin, M

“…Emerging evidence indicates memory donor-reactive T cells are detrimental to transplant outcome and that quantifying the frequency of IFN[gamma]-producing,…”
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A novel HLA‐A null allele, HLA‐A66:28N by Yin, Y., Takemura, P., Reed, E. F., Zhang, Q.

“…The novel HLA‐A*66:28N allele differs from HLA‐A*66:03 by a single nucleotide deletion at codon 185…”
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The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody‐Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions by Bruneval, P., Angelini, A., Miller, D., Potena, L., Loupy, A., Zeevi, A., Reed, E. F., Dragun, D., Reinsmoen, N., Smith, R. N., West, L., Tebutt, S., Thum, T., Haas, M., Mengel, M., Revelo, P., Fedrigo, M., Duong Van Huyen, J. P., Berry, G. J.

“…The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to…”
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Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation by Ettenger, R., Chin, H., Kesler, K., Bridges, N., Grimm, P., Reed, E. F., Sarwal, M., Sibley, R., Tsai, E., Warshaw, B., Kirk, A. D.

“…The Immune Development in Pediatric Transplantation (IMPACT) study was conducted to evaluate relationships among alloimmunity, protective immunity, immune…”
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Monocyte Recruitment by HLA IgG‐Activated Endothelium: The Relationship Between IgG Subclass and FcγRIIa Polymorphisms by Valenzuela, N. M., Trinh, K. R., Mulder, A., Morrison, S. L., Reed, E. F.

“…It is currently unclear which donor specific HLA antibodies confer the highest risk of antibody‐mediated rejection (AMR) and allograft loss. In this study, we…”
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An Anti‐C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA by Thomas, K. A., Valenzuela, N. M., Gjertson, D., Mulder, A., Fishbein, M. C., Parry, G. C., Panicker, S., Reed, E. F.

“…Antibody‐mediated rejection (AMR) of solid organ transplants (SOT) is characterized by damage triggered by donor‐specific antibodies (DSA) binding donor Class…”
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HLA High‐Resolution Typing for Sensitized Patients: A Solution in Search of a Problem? by Cecka, J. M., Reed, E. F., Zachary, A. A.

“…This editorial challenges the view that more is better when it comes to the level of HLA testing for organ donors for sensitized patients, as proposed by…”
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Monitoring of soluble HLA alloantigens and anti-HLA antibodies identifies heart allograft recipients at risk of transplant-associated coronary artery disease by REED, E. F, HONG, B, HO, E, HARRIS, P. E, WEINBERGER, J, SUCIU-FOCA, N

“…The development of accelerated transplant-related coronary artery disease (T-CAD) is the major obstacle to long-term survival of cardiac allografts. We have…”
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