Search Results - "Reed, Carl D."

neu mutation in schwannomas induced transplacentally in Syrian golden hamsters by N-nitrosoethylurea : high incidence but low allelic representation by BUZARD, G. S, ENOMOTO, T, HONGYO, T, PERANTONI, A. O, DIWAN, B. A, DEVOR, D. E, REED, C. D, DOVE, L. F, RICE, J. M

“…Peripheral nerve tumors (PNT) and melanomas induced transplacentally on day 14 of gestation in Syrian golden hamsters by N-nitrosoethylurea were analyzed for…”
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GGT to GTT transversions in codon 12 of the K-ras oncogene in rat renal sarcomas induced with nickel subsulfide or nickel subsulfide/iron are consistent with oxidative damage to DNA by Higinbotham, K G, Rice, J M, Diwan, B A, Kasprzak, K S, Reed, C D, Perantoni, A O

“…Nickel is a toxic, mutagenic, and carcinogenic metal of significant occupational and environmental concern. Although several cellular targets of nickel have…”
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Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys by Chhabra, Saranjit K., Reed, Carl D., Anderson, Lucy M., Shiao, Yih-Horng

“…Cytochrome P450 2E1 (CYP2E1) metabolizes low molecular weight toxicants. CYP2E1 gene polymorphisms have been linked to risk of various cancers and liver…”
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Identification of an interferon in murine placentas by Giron, David J, Reed, Carl D, Fowler, Arnold K

“…It is becoming increasingly apparent that interferon exerts a major role in cellular regulatory processes. Besides its well known antiviral properties,…”
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DNA adducts and liver DNA replication in rats during chronic exposure to N-nitrosodimethylamine (NDMA) and their relationships to the dose-dependence of NDMA hepatocarcinogenesis by Souliotis, Vassilis L, Henneman, John R, Reed, Carl D, Chhabra, Saranjit K, Diwan, Bhalchandra A, Anderson, Lucy M, Kyrtopoulos, Soterios A

“…Exposure of rats to the hepatocarcinogen N-nitrosodimethylamine (NDMA) (0.2-2.64 ppm in the drinking water) for up to 180 days resulted in rapid accumulation…”
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Activated neu Oncogene Sequences in Primary Tumors of the Peripheral Nervous System Induced in Rats by Transplacental Exposure to Ethylnitrosourea by Perantoni, Alan O., Rice, Jerry M., Reed, Carl D., Watatani, Masahiro, Wenk, Martin L.

“…Neurogenic tumors were selectively induced in high incidence in F344 rats by a single transplacental exposure to the direct-acting alkylating agent…”
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Variant mutational activation of the K-ras oncogene in renal mesenchymal tumors induced in newborn F344 rats by methyl(methoxymethyl)nitrosamine by Higinbotham, Kathleen G., Rice, Jerry M., Reed, Carl D., Watatani, Masahiro, Enomoto, Takayuki, Anderson, Lucy M., Perantoni, Alan O.

“…Renal mesenchymal tumors were induced at high incidence in F344 rats by a single intraperitoneal injection of methyl(methoxymethyl)nitrosamine (DMN-OMe) within…”
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Infrequent activation of K-ras, H-ras, and other oncogenes in hepatocellular neoplasms initiated by methyl(acetoxymethyl)nitrosamine, a methylating agent, and promoted by phenobarbital in F344 rats by WATATANI, M, PERANTONI, A. O, REED, C. D, ENOMOTO, T, WENK, M. L, RICE, J. M

“…Fischer 344/Ncr rats of both sexes were subjected to partial hepatectomy and then initiated 21-24 h later by a single injection of…”
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N-nitrosocimetidine as an initiator of murine skin tumors with associated H-ras oncogene activation by Anderson, L M, Enomoto, T, Perantoni, A O, Riggs, C W, Kovatch, R M, Reed, C D, Giner-Sorolla, A, Rice, J M

“…N-Nitrosocimetidine (NCM) is a derivative of the drug cimetidine, a methylguanidine derivative used in the treatment of peptic ulcer, and is known to be…”
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