Search Results - "Redondo, Alberto García"

MicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosis by Toivonen, Janne M, Manzano, Raquel, Oliván, Sara, Zaragoza, Pilar, García-Redondo, Alberto, Osta, Rosario

“…Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease that progressively debilitates neuronal cells that control voluntary muscle activity…”
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ATXN2 intermediate expansions in amyotrophic lateral sclerosis by Glass, Jonathan D, Dewan, Ramita, Ding, Jinhui, Gibbs, J Raphael, Dalgard, Clifton, Keagle, Pamela J, Shankaracharya, García-Redondo, Alberto, Traynor, Bryan J, Chia, Ruth, Landers, John E

“…Intermediate CAG (polyQ) expansions in the gene ataxin-2 (ATXN2) are now recognized as a risk factor for amyotrophic lateral sclerosis. The threshold for…”
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Molecular Alterations in Sporadic and SOD1 -ALS Immortalized Lymphocytes: Towards a Personalized Therapy by Lastres-Becker, Isabel, Porras, Gracia, Arribas-Blázquez, Marina, Maestro, Inés, Borrego-Hernández, Daniel, Boya, Patricia, Cerdán, Sebastián, García-Redondo, Alberto, Martínez, Ana, Martin-Requero, Ángeles

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurological condition where motor neurons (MNs) degenerate. Most of the ALS cases are sporadic (sALS), whereas…”
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Differentially expressed lncRNAs in SOD1G93A mice skeletal muscle: H19, Myhas and Neat1 as potential biomarkers in amyotrophic lateral sclerosis by López-Royo, Tresa, Moreno-Martínez, Laura, Zaragoza, Pilar, García-Redondo, Alberto, Manzano, Raquel, Osta, Rosario

“…Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized by progressive motor function and muscle mass loss. Despite extensive…”
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Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1G93A ALS mice and after partial muscle denervation by Mancuso, Renzo, Martínez-Muriana, Anna, Leiva, Tatiana, Gregorio, David, Ariza, Lorena, Morell, Marta, Esteban-Pérez, Jesús, García-Redondo, Alberto, Calvo, Ana C, Atencia-Cibreiro, Gabriela, Corfas, Gabriel, Osta, Rosario, Bosch, Assumpció, Navarro, Xavier

“…Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of motoneurons, which is preceded by loss…”
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Inflammatory and non-inflammatory monocytes as novel prognostic biomarkers of survival in SOD1G93A mouse model of Amyotrophic Lateral Sclerosis by Gasco, Samanta, Zaragoza, Pilar, García-Redondo, Alberto, Calvo, Ana C, Osta, Rosario

“…Amyotrophic Lateral Sclerosis (ALS) has lately become a suitable scenario to study the interplay between the hematopoietic system and disease progression…”
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Characterizing SOD1 mutations in Spain: The impact of genotype, age and sex in the natural history of the disease by Vázquez‐Costa, Juan F., Borrego‐Hernández, Daniel, Paradas, Carmen, Gómez‐Caravaca, María Teresa, Rojas‐Garcia, Ricardo, Varona, Luis, Povedano, Mónica, García‐Sobrino, Tania, Jericó Pascual, Ivonne, Gutiérrez, Antonio, Riancho, Javier, Turon‐Sans, Janina, Assialioui, Abdelilah, Pérez‐Tur, Jordi, Sevilla, Teresa, Esteban Pérez, Jesús, García‐Redondo, Alberto, López, Alberto Andrés, Calabria, M. Dolores, Díaz‐Marín, Carmen, Caravaca, Eva Fages, Dávila, Lucía Galán, Martínez, Alberto García, Gimenez‐Muñoz, Álvaro, Sola, Antonio Guerrero, Cadavid, Javier Mascías, Mora Pardina, Jesús S., Blanco, José Luis Muñoz, Juntas‐Morales, Raúl, Morgado, Yolanda, Pardo, Julio, Valladares, Amador, Vilar‐Ventura, Rosa Maria

“…Background and purpose The aim of this study was to describe the frequency and distribution of SOD1 mutations in Spain, and to explore factors contributing to…”
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Genetic biomarkers for ALS disease in transgenic SOD1(G93A) mice by Calvo, Ana C, Manzano, Raquel, Atencia-Cibreiro, Gabriela, Oliván, Sara, Muñoz, María J, Zaragoza, Pilar, Cordero-Vázquez, Pilar, Esteban-Pérez, Jesús, García-Redondo, Alberto, Osta, Rosario

“…The pathophysiological mechanisms of both familial and sporadic Amyotrophic Lateral Sclerosis (ALS) are unknown, although growing evidence suggests that…”
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Comparative study of hematopoietic stem and progenitor cells between sexes in mice under physiological conditions along time by Gasco, Samanta, Rando, Amaya, Zaragoza, Pilar, García‐Redondo, Alberto, Calvo, Ana Cristina, Osta, Rosario

“…Hematopoietic stem and progenitor cells (HSPCs) are attractive targets in regenerative medicine, although the differences in their homeostatic maintenance…”
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Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish Population by Borrego-Hernández, Daniel, Vázquez-Costa, Juan Francisco, Domínguez-Rubio, Raúl, Expósito-Blázquez, Laura, Aller, Elena, Padró-Miquel, Ariadna, García-Casanova, Pilar, Colomina, María J, Martín-Arriscado, Cristina, Osta, Rosario, Cordero-Vázquez, Pilar, Esteban-Pérez, Jesús, Povedano-Panadés, Mónica, García-Redondo, Alberto

“…Intermediate CAG expansions in the gene ataxin-2 ( ) are a known risk factor for ALS, but little is known about their role in FTD risk. Moreover, their…”
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CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing by Tosat-Bitrián, Carlota, Avis-Bodas, Alicia, Porras, Gracia, Borrego-Hernández, Daniel, García-Redondo, Alberto, Martín-Requero, Angeles, Palomo, Valle

“…CdSe quantum dots (QDs) are valuable tools for deciphering molecular mechanisms in cells. Their conjugation with antibodies offers a unique staining source…”
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Granulocyte Colony-Stimulating Factor Ameliorates Skeletal Muscle Dysfunction in Amyotrophic Lateral Sclerosis Mice and Improves Proliferation of SOD1-G93A Myoblasts in vitro by Rando, Amaya, Gasco, Samanta, de la Torre, Miriam, García-Redondo, Alberto, Zaragoza, Pilar, Toivonen, Janne M, Osta, Rosario

“…Amyotrophic lateral sclerosis (ALS) causes loss of upper and lower motor neurons as well as skeletal muscle (SKM) dysfunction and atrophy. SKM is one of the…”
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Altered expression of myogenic regulatory factors in the mouse model of amyotrophic lateral sclerosis by Manzano, Raquel, Toivonen, Janne M, Oliván, Sara, Calvo, Ana C, Moreno-Igoa, Maria, Muñoz, Maria J, Zaragoza, Pilar, García-Redondo, Alberto, Osta, Rosario

“…In the superoxide dismutase 1 (SOD1)-G93A mouse model of amyotrophic lateral sclerosis (ALS), skeletal muscle is a key target of mutant SOD1 toxicity. However,…”
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Oxidative stress in skin fibroblasts cultures from patients with Parkinson's disease by del Hoyo, Pilar, García-Redondo, Alberto, de Bustos, Fernando, Molina, José Antonio, Sayed, Youssef, Alonso-Navarro, Hortensia, Caballero, Luis, Arenas, Joaquín, Agúndez, José A G, Jiménez-Jiménez, Félix Javier

“…In the substantia nigra of Parkinson's disease (PD) patients, increased lipid peroxidation, decreased activities of the mitochondrial complex I of the…”
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Genetic Biomarkers for ALS Disease in Transgenic SOD1G93A Mice by Calvo, Ana C., Manzano, Raquel, Atencia-Cibreiro, Gabriela, Oliván, Sara, Muñoz, María J., Zaragoza, Pilar, Cordero-Vázquez, Pilar, Esteban-Pérez, Jesús, García-Redondo, Alberto, Osta, Rosario

“…The pathophysiological mechanisms of both familial and sporadic Amyotrophic Lateral Sclerosis (ALS) are unknown, although growing evidence suggests that…”
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Analysis of known amyotrophic lateral sclerosis and frontotemporal dementia genes reveals a substantial genetic burden in patients manifesting both diseases not carrying the C9orf72 expansion mutation by Dols-Icardo, Oriol, García-Redondo, Alberto, Rojas-García, Ricardo, Borrego-Hernández, Daniel, Illán-Gala, Ignacio, Muñoz-Blanco, José Luís, Rábano, Alberto, Cervera-Carles, Laura, Juárez-Rufián, Alexandra, Spataro, Nino, De Luna, Noemí, Galán, Lucía, Cortes-Vicente, Elena, Fortea, Juan, Blesa, Rafael, Grau-Rivera, Oriol, Lleó, Alberto, Esteban-Pérez, Jesús, Gelpi, Ellen, Clarimón, Jordi

“…Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are part of a clinical, pathological and genetic continuum.ObjectivesThe purpose of the…”
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Familial primary lateral sclerosis or dementia associated with Arg573Gly TBK1 mutation by Gómez-Tortosa, Estrella, Van der Zee, Julie, Ruggiero, María, Gijselinck, Ilse, Esteban-Pérez, Jesús, García-Redondo, Alberto, Borrego-Hernández, Daniel, Navarro, Eloísa, Sainz, M. José, Pérez-Pérez, Julián, Cruts, Marc, Van Broeckhoven, Christine, Guerrero-López, Rosa

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The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis by Davidson, Jennilee M., Wu, Sharlynn S. L., Rayner, Stephanie L., Cheng, Flora, Duncan, Kimberley, Russo, Carlo, Newbery, Michelle, Ding, Kunjie, Scherer, Natalie M., Balez, Rachelle, García-Redondo, Alberto, Rábano, Alberto, Rosa-Fernandes, Livia, Ooi, Lezanne, Williams, Kelly L., Morsch, Marco, Blair, Ian P., Di Ieva, Antonio, Yang, Shu, Chung, Roger S., Lee, Albert

“…Amyotrophic lateral sclerosis (ALS)- and frontotemporal dementia (FTD)-linked mutations in CCNF have been shown to cause dysregulation to protein homeostasis…”
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Hematopoietic stem and progenitor cells as novel prognostic biomarkers of longevity in a murine model for amyotrophic lateral sclerosis by Gasco, Samanta, Rando, Amaya, Zaragoza, Pilar, García-Redondo, Alberto, Calvo, Ana Cristina, Osta, Rosario

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a difficult diagnosis and prognosis. In this regard, new and more reliable…”
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Early onset multisystem mitochondrial disorder caused by a nonsense mutation in the mitochondrial DNA Cytochrome C oxidase II gene by Campos, Yolanda, García-Redondo, Alberto, Fernández-Moreno, Miguel A., Martínez-Pardo, Mercedes, Goda, Guillermo, Rubio, Juan C., Martín, Miguel A., Del Hoyo, Pilar, Cabello, Ana, Bornstein, Belen, Garesse, Rafael, Arenas, Joaquín

“…We report the first nonsense mutation (G7896A) in the mtDNA gene for subunit II of cytochrome c oxidase (COX) in a patient with early‐onset multisystem disease…”
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