Search Results - "Redolfi, Nelly"
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Intracellular Calcium Dysregulation by the Alzheimer's Disease-Linked Protein Presenilin 2
Published in International journal of molecular sciences (24-01-2020)“…Alzheimer's disease (AD) is the most common form of dementia. Even though most AD cases are sporadic, a small percentage is familial due to autosomal dominant…”
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2
Spontaneous Afferent Activity Carves Olfactory Circuits
Published in Frontiers in cellular neuroscience (09-03-2021)“…Electrical activity has a key role in shaping neuronal circuits during development. In most sensory modalities, early in development, internally generated…”
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3
Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca2+ Handling
Published in Frontiers in physiology (20-12-2019)“…The endoplasmic reticulum (ER) extends as a network of interconnected tubules and sheet-like structures in eukaryotic cells. ER tubules dynamically change…”
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4
Axonal Odorant Receptors Mediate Axon Targeting
Published in Cell reports (Cambridge) (24-12-2019)“…In mammals, odorant receptors not only detect odors but also define the target in the olfactory bulb, where sensory neurons project to give rise to the sensory…”
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Mitochondrial Ca2+ Signaling and Bioenergetics in Alzheimer’s Disease
Published in Biomedicines (24-11-2022)“…Alzheimer’s disease (AD) is a hereditary and sporadic neurodegenerative illness defined by the gradual and cumulative loss of neurons in specific brain areas…”
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6
Accelerated Aging Characterizes the Early Stage of Alzheimer's Disease
Published in Cells (Basel, Switzerland) (11-01-2022)“…For Alzheimer's disease (AD), aging is the main risk factor, but whether cognitive impairments due to aging resemble early AD deficits is not yet defined. When…”
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7
Familial Alzheimer’s disease presenilin-2 mutants affect Ca2+ homeostasis and brain network excitability
Published in Aging clinical and experimental research (01-06-2021)“…Alzheimer’s disease (AD) is the most frequent cause of dementia in the elderly. Few cases are familial (FAD), due to autosomal dominant mutations in…”
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Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks
Published in Cells (Basel, Switzerland) (01-10-2020)“…Presenilin-2 (PS2) is one of the three proteins that are dominantly mutated in familial Alzheimer’s disease (FAD). It forms the catalytic core of the…”
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Lighting Up Ca2+ Dynamics in Animal Models
Published in Cells (Basel, Switzerland) (19-08-2021)“…Calcium (Ca2+) signaling coordinates are crucial processes in brain physiology. Particularly, fundamental aspects of neuronal function such as synaptic…”
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10
Role of the odorant receptor in neuronal connectivity in the olfactory bulb
Published in Swiss medical weekly (2015)“…Olfaction is a highly sophisticated sensory modality able to detect and discriminate thousands of different odours, even at very low concentration. How such a…”
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11
Mitochondrial Ca[sup.2+] Signaling and Bioenergetics in Alzheimer’s Disease
Published in Biomedicines (01-11-2022)“…Alzheimer’s disease (AD) is a hereditary and sporadic neurodegenerative illness defined by the gradual and cumulative loss of neurons in specific brain areas…”
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12
Oligophrenin-1 regulates number, morphology and synaptic properties of adult-born inhibitory interneurons in the olfactory bulb
Published in Human molecular genetics (01-12-2016)“…Among the X-linked genes associated with intellectual disability, Oligophrenin-1 (OPHN1) encodes for a Rho GTPase-activating protein, a key regulator of…”
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13
Mitochondrial Ca 2+ Signaling and Bioenergetics in Alzheimer's Disease
Published in Biomedicines (24-11-2022)“…Alzheimer's disease (AD) is a hereditary and sporadic neurodegenerative illness defined by the gradual and cumulative loss of neurons in specific brain areas…”
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14
A New Transgenic Mouse Line for Imaging Mitochondrial Calcium Signals
Published in Function (Oxford, England) (01-01-2021)“…Mitochondria play a key role in cellular calcium (Ca ) homeostasis. Dysfunction in the organelle Ca handling appears to be involved in several pathological…”
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15
Circuit formation and function in the olfactory bulb of mice with reduced spontaneous afferent activity
Published in The Journal of neuroscience (07-01-2015)“…The type of neuronal activity required for circuit development is a matter of significant debate. We addressed this issue by analyzing the topographic…”
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16
Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca 2+ Handling
Published in Frontiers in physiology (2019)“…The endoplasmic reticulum (ER) extends as a network of interconnected tubules and sheet-like structures in eukaryotic cells. ER tubules dynamically change…”
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Journal Article -
17
Lighting Up Ca 2+ Dynamics in Animal Models
Published in Cells (Basel, Switzerland) (19-08-2021)“…Calcium (Ca ) signaling coordinates are crucial processes in brain physiology. Particularly, fundamental aspects of neuronal function such as synaptic…”
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Journal Article -
18
Ethnic influences on the perceptual properties of human chemosignals
Published in Physiology & behavior (15-10-2019)“…Individuals of African and Caucasian descent show different chemical signatures in their body odors (BO). Does such biological difference have a perceptual…”
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