Search Results - "Redmond, Stephanie A"
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Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
Published in Nature medicine (01-08-2014)“…High-throughput screening platform for the testing of small bioactive molecules that promote oligodendrocyte differentiation and remyelination: a new path to…”
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Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor
Published in Cell reports (Cambridge) (09-04-2019)“…The adult mouse brain contains an extensive neurogenic niche in the lateral walls of the lateral ventricles. This epithelium, which has a unique pinwheel…”
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Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis
Published in eLife (14-07-2021)“…The ventricular-subventricular zone (V-SVZ), on the walls of the lateral ventricles, harbors the largest neurogenic niche in the adult mouse brain. Previous…”
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Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
Published in Neuron (Cambridge, Mass.) (06-07-2016)“…Persistent accumulation of misfolded proteins causes endoplasmic reticulum (ER) stress, a prominent feature in many neurodegenerative diseases including…”
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Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination
Published in Neuron (Cambridge, Mass.) (17-08-2016)“…Myelination occurs selectively around neuronal axons to increase the efficiency and velocity of action potentials. While oligodendrocytes are capable of…”
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Remodeling myelination: implications for mechanisms of neural plasticity
Published in Nature neuroscience (01-02-2016)“…Dynamic membrane transformations are not exclusively controlled by cytoskeletal rearrangement, but also by biophysical constraints, adhesive forces, membrane…”
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Astrocyte-encoded positional cues maintain sensorimotor circuit integrity
Published in Nature (London) (08-05-2014)“…Astrocytes, the most abundant cells in the central nervous system, promote synapse formation and help to refine neural connectivity. Although they are…”
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A culture system to study oligodendrocyte myelination processes using engineered nanofibers
Published in Nature methods (01-09-2012)“…Primary rat oligodendocytes were cultured in the presence of electron-spun nanofibers of varying sizes as a model to study myelination processes in the…”
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Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity
Published in The Journal of neuroscience (29-06-2016)“…Myelin controls the time required for an action potential to travel from the neuronal soma to the axon terminal, defining the temporal manner in which…”
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Revitalizing Remyelination—the Answer Is Circulating
Published in Science (American Association for the Advancement of Science) (13-04-2012)“…Aged oligodendroglia in the mouse central nervous system are competent to repair neural injury when exposed to “youthful” circulatory factors. Walled off by…”
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Author Correction: Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
Published in Nature medicine (01-09-2024)Get full text
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12
Neuroscience. Revitalizing remyelination--the answer is circulating
Published in Science (American Association for the Advancement of Science) (13-04-2012)Get full text
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