Search Results - "Redmond, H"

B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration by Li, Yan, Huang, Jie, Foley, Niamh M., Xu, Yunyun, Li, Yi Ping, Pan, Jian, Redmond, H. Paul, Wang, Jiang Huai, Wang, Jian

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by an excessive inflammatory response within the lungs and severely…”
Get full text

An Early Neutrophil Recruitment into the Infectious Site Is Critical for Bacterial Lipoprotein Tolerance-Afforded Protection against Microbial Sepsis by Chen, Wenting, Zhao, Shuqi, Ita, Michael, Li, Yue, Ji, Jingjing, Jiang, Yong, Redmond, H Paul, Wang, Jiang Huai, Liu, Jinghua

“…Bacterial lipoprotein (BLP)-induced tolerance represents an essential regulatory mechanism during bacterial infection and has been shown to protect against…”
Get full text

MicroRNA-146a is upregulated by and negatively regulates TLR2 signaling by Quinn, Edel M, Wang, Jiang Huai, O'Callaghan, Grace, Redmond, H Paul

“…TLR signaling is a crucial component of the innate immune response to infection. MicroRNAs (miRNAs) have been shown to be upregulated during TLR signaling…”
Get full text

Meta‐analysis of the diagnostic accuracy of ultrasound‐guided fine‐needle aspiration and core needle biopsy in diagnosing axillary lymph node metastasis by Balasubramanian, I., Fleming, C. A., Corrigan, M. A., Redmond, H. P., Kerin, M. J., Lowery, A. J.

“…Background Axillary lymph node status remains a significant prognostic indicator in breast cancer. Here, the diagnostic accuracy of ultrasound‐guided…”
Get full text

TLR-4 signalling accelerates colon cancer cell adhesion via NF-κB mediated transcriptional up-regulation of Nox-1 by O'Leary, D Peter, Bhatt, Lavinia, Woolley, John F, Gough, David R, Wang, Jiang H, Cotter, Thomas G, Redmond, H Paul

“…Surgery induced inflammation is a potent promoter of tumour recurrence and metastasis in colorectal cancer. The recently discovered family of Nox enzymes…”
Get full text

Risk of colorectal cancer associated with BRCA1 and/or BRCA2 mutation carriers: systematic review and meta‐analysis by Cullinane, C. M., Creavin, B., O'Connell, E. P., Kelly, L., O'Sullivan, M. J., Corrigan, M. A., Redmond, H. P.

“…Background Carriers of the BRCA1 and/or BRCA2 mutation incur a lifetime risk of up to 85 per cent for breast cancer, and between 20 and 40 per cent for ovarian…”
Get full text

Vascular Endothelial Growth Factor Stimulates Bone Repair by Promoting Angiogenesis and Bone Turnover by Street, John, Bao, Min, deGuzman, Leo, Bunting, Stuart, Peale, Franklin V., Ferrara, Napoleone, Steinmetz, Hope, Hoeffel, John, Cleland, Jeffrey L., Daugherty, Ann, van Bruggen, Nicholas, Redmond, H. Paul, Richard A. D. Carano, Filvaroff, Ellen H.

“…Several growth factors are expressed in distinct temporal and spatial patterns during fracture repair. Of these, vascular endothelial growth factor, VEGF, is…”
Get full text

Perioperative cell-free DNA trends predict recurrence of non-metastatic colorectal cancer significantly earlier than CEA trends over the first 2 years post-operatively in stage II and stage III colon cancer by Fleming, Christina A., Jordan, Patrick, O’Leary, Donal P., Corrigan, Mark A., Wang, J. H., Redmond, H. P.

“…Purpose We aimed to compare the diagnostic accuracy of perioperative ΔcfDNA to ΔCEA (over the first 2 years post-operatively) for identifying disease…”
Get full text

Antagonism of Integrin CD11b Affords Protection against Endotoxin Shock and Polymicrobial Sepsis via Attenuation of HMGB1 Nucleocytoplasmic Translocation and Extracellular Release by Zhou, Huiting, Li, Yanhong, Gui, Huan, Zhao, He, Wu, Ming, Li, Gang, Li, Yiping, Bai, Zhenjiang, Yin, Zhimin, Redmond, H Paul, Wang, Jian, Wang, Jiang Huai, Zhao, Zhihui

“…High mobility group box 1 (HMGB1), a chromatin-binding nuclear protein, plays a critical role in sepsis by acting as a key "late-phase" inflammatory mediator…”
Get full text

Silencing of TLR4 Increases Tumor Progression and Lung Metastasis in a Murine Model of Breast Cancer by Ahmed, Abubakr, Wang, Jiang Huai, Redmond, H. Paul

“…Background Toll-like receptor 4 (TLR4) is a member of a family of pattern recognition receptors that are involved in the host defense against microbial…”
Get full text

Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance by Huang, Jie, Ita, Michael, Zhou, Huiting, Zhao, He, Hassan, Fara, Bai, Zhenjiang, O'Leary, D Peter, Li, Yiping, Redmond, H Paul, Wang, Jiang Huai, Wang, Jian

“…Sepsis, septic shock, and their sequelae are the leading causes of death in intensive care units, with limited therapeutic options. Disease resistance and…”
Get full text

Activation of Both TLR and NOD Signaling Confers Host Innate Immunity-Mediated Protection Against Microbial Infection by Zhou, Huiting, Coveney, Andrew P, Wu, Ming, Huang, Jie, Blankson, Siobhan, Zhao, He, O'Leary, D Peter, Bai, Zhenjiang, Li, Yiping, Redmond, H Paul, Wang, Jiang Huai, Wang, Jian

“…The detection of microbial pathogens relies on the recognition of highly conserved microbial structures by the membrane sensor Toll-like receptors (TLRs) and…”
Get full text

B7-H3 Augments Inflammatory Responses and Exacerbates Brain Damage via Amplifying NF-κB p65 and MAPK p38 Activation during Experimental Pneumococcal Meningitis by Chen, Xuqin, Li, Yan, Blankson, Siobhan, Liu, Min, Huang, Danping, Redmond, H Paul, Huang, Jing, Wang, Jiang Huai, Wang, Jian

“…The costimulatory protein B7-H3 has been shown to play a contributory role in the development and progression of experimental pneumococcal meningitis by…”
Get full text

Myeloid-related protein 8 induces self-tolerance and cross-tolerance to bacterial infection via TLR4- and TLR2-mediated signal pathways by Coveney, Andrew P., Wang, Wei, Kelly, Justin, Liu, Jing Hua, Blankson, Siobhan, Wu, Qiong Di, Redmond, H. Paul, Wang, Jiang Huai

“…Myeloid-related protein 8 (Mrp8) is the active component of Mrp8/14 protein complex released by phagocytes at the site of infection and stimulates inflammatory…”
Get full text

Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4 by Cronin, Patricia A, Wang, Jiang H, Redmond, H Paul

“…Chemokine SDF1alpha and its unique receptor CXCR4 have been implicated in organ-specific metastases of many cancers including breast cancer. Hypoxia is a…”
Get full text

A meta-analysis to determine the oncological implications of conversion in laparoscopic colorectal cancer surgery by Clancy, C., O'Leary, D. P., Burke, J. P., Redmond, H. P., Coffey, J. C., Kerin, M. J., Myers, E.

“…Aim Laparoscopic colon and rectal cancer surgery is oncologically equivalent to open resection, but the impact of conversion is undetermined. The aim of this…”
Get full text

Siliconosis and the long-term implications of silent breast implant rupture by Gleeson, Jack P, Redmond, H Paul, O'Reilly, Séamus

Get more information

Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-κB-dependent activation of the urokinase plasminogen activator system by Killeen, S D, Wang, J H, Andrews, E J, Redmond, H P

“…Perioperative exposure to lipopolysaccharide (LPS) is associated with accelerated metastatic colorectal tumour growth. LPS directly affects cells through…”
Get full text

Primary hyperparathyroidism causing posterior reversible encephalopathy syndrome: a case report by Cagney, D, Razzaq, Z, Majeed, M, O'Leary, D P, Redmond, H P

“…Posterior reversible encephalopathy syndrome (PRES) is a reversible leukoencephalopathy characterised by subcortical vasogenic oedema and neurological signs…”
Get full text

Provider volume and outcomes for oncological procedures by Killeen, S. D., O'Sullivan, M. J., Coffey, J. C., Kirwan, W. O., Redmond, H. P.

“…Background: Oncological procedures may have better outcomes if performed by high‐volume providers. Methods: A review of the English language literature…”
Get full text