Search Results - "Redman, Mary"
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Phase II Randomized Study of Ramucirumab and Pembrolizumab Versus Standard of Care in Advanced Non-Small-Cell Lung Cancer Previously Treated With Immunotherapy-Lung-MAP S1800A
Published in Journal of clinical oncology (20-07-2022)“…Resistance to immune checkpoint inhibition (ICI) in advanced non-small-cell lung cancer (NSCLC) represents a major unmet need. Combining ICI with vascular…”
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The Master Protocol Concept
Published in Seminars in oncology (01-10-2015)“…During the past decade, biomedical technologies have undergone an explosive evolution—from the publication of the first complete human genome in 2003, after…”
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Moving Toward Rationale Phase 3 Designs for Advanced NSCLC
Published in Journal of thoracic oncology (01-12-2023)Get more information
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Viral oncoprotein antibodies as a marker for recurrence of Merkel cell carcinoma: A prospective validation study
Published in Cancer (15-04-2017)“…BACKGROUND Merkel cell carcinoma (MCC) is an aggressive skin cancer with a recurrence rate of >40%. Of the 2000 MCC cases per year in the United States, most…”
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T‐cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death‐ligand 1 expression in patients with soft tissue sarcomas
Published in Cancer (01-09-2017)“…BACKGROUND Patients with metastatic sarcomas have poor outcomes and although the disease may be amenable to immunotherapies, information regarding the…”
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Randomized Trial of Afatinib Plus Cetuximab Versus Afatinib Alone for First-Line Treatment of EGFR -Mutant Non-Small-Cell Lung Cancer: Final Results From SWOG S1403
Published in Journal of clinical oncology (01-12-2020)“…The irreversible ErbB family tyrosine kinase inhibitor (TKI) afatinib plus the EGFR monoclonal antibody cetuximab was previously shown to overcome resistance…”
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Lung Master Protocol (Lung-MAP)-A Biomarker-Driven Protocol for Accelerating Development of Therapies for Squamous Cell Lung Cancer: SWOG S1400
Published in Clinical cancer research (01-04-2015)“…The Lung Master Protocol (Lung-MAP, S1400) is a groundbreaking clinical trial designed to advance the efficient development of targeted therapies for squamous…”
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Incidence of Suicide in Persons With Cancer
Published in Journal of clinical oncology (10-10-2008)“…The purpose of this study was to characterize suicide rates among patients with cancer in the United States and identify patient and disease characteristics…”
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Biomarker-driven therapies for previously treated squamous non-small-cell lung cancer (Lung-MAP SWOG S1400): a biomarker-driven master protocol
Published in The lancet oncology (01-12-2020)“…The Lung Cancer Master Protocol (Lung-MAP; S1400) is a completed biomarker-driven master protocol designed to address an unmet need for better therapies for…”
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Phase III Trial of Irinotecan/Cisplatin Compared With Etoposide/Cisplatin in Extensive-Stage Small-Cell Lung Cancer: Clinical and Pharmacogenomic Results From SWOG S0124
Published in Journal of clinical oncology (20-05-2009)“…Irinotecan plus cisplatin (IP) improved survival over etoposide plus cisplatin (EP) in Japanese patients with extensive-stage small-cell lung cancer (E-SCLC)…”
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Racial disparities in the screening mammography continuum within a heterogeneous health care system
Published in Cancer (01-09-2023)“…Abstract Background Decreased mammography drives breast cancer disparities. Black women have lower rates of mammography completion than White women, and this…”
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Circulating Tumor DNA Kinetics Predict Progression-Free and Overall Survival in EGFR TKI-Treated Patients with EGFR-Mutant NSCLC (SWOG S1403)
Published in Clinical cancer research (01-09-2022)“…Dynamic changes in circulating tumor DNA (ctDNA) are under investigation as an early indicator of treatment outcome. Serial plasma ctDNA (baseline, 8 weeks,…”
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SWOG S1400D (NCT02965378), a Phase II Study of the Fibroblast Growth Factor Receptor Inhibitor AZD4547 in Previously Treated Patients With Fibroblast Growth Factor Pathway-Activated Stage IV Squamous Cell Lung Cancer (Lung-MAP Substudy)
Published in Journal of thoracic oncology (01-10-2019)“…S1400D is a biomarker-driven therapeutic substudy of Lung-MAP evaluating the fibroblast growth factor (FGF) receptor (FGFR) inhibitor AZD4547 in patients with…”
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Scientific Advances in Lung Cancer 2015
Published in Journal of thoracic oncology (01-05-2016)“…Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant…”
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Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Naïve Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905)
Published in Journal of clinical oncology (01-10-2019)“…Antiangiogenic agents combined with chemotherapy have efficacy in the treatment of unresectable malignant pleural mesothelioma (MPM). Cediranib (AstraZeneca,…”
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Cetuximab plus carboplatin and paclitaxel with or without bevacizumab versus carboplatin and paclitaxel with or without bevacizumab in advanced NSCLC (SWOG S0819): a randomised, phase 3 study
Published in The lancet oncology (01-01-2018)“…EGFR antibodies have shown promise in patients with advanced non-small-cell lung cancer (NSCLC), particularly with squamous cell histology. We hypothesised…”
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Enrollment Trends and Disparity Among Patients With Lung Cancer in National Clinical Trials, 1990 to 2012
Published in Journal of clinical oncology (20-11-2016)“…Purpose Under-representation of elderly, women, and racial/ethnic minority patients with cancer in clinical trials is of national concern. The goal of this…”
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B7-H3 is widely expressed in soft tissue sarcomas
Published in BMC cancer (30-10-2024)“…Targeted therapy development in soft tissue sarcoma (STS) has been burdened by the heterogeneity of this group of rare tumors. B7 homolog 3 protein (B7-H3) is…”
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Racial and sex differences in tumor genomics in urothelial carcinoma
Published in Urologic oncology (01-11-2023)“…Differences in bladder cancer outcomes have been demonstrated by sex and race/ethnicity, with studies showing a higher burden of adverse outcomes among women…”
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Dynamic plasma microRNAs are biomarkers for prognosis and early detection of recurrence in colorectal cancer
Published in British journal of cancer (10-10-2017)“…Background: Plasma microRNAs (miRNAs) are promising non-invasive biomarkers for colorectal cancer (CRC) prognosis. However, the published studies to date have…”
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