Search Results - "Redman, Christopher W"

Pre-eclampsia: pathophysiology and clinical implications by Burton, Graham J, Redman, Christopher W, Roberts, James M, Moffett, Ashley

“…AbstractPre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical presentation is highly variable but hypertension and…”
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Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia: A Prospective Multicenter Study by Chappell, Lucy C, Duckworth, Suzy, Seed, Paul T, Griffin, Melanie, Myers, Jenny, Mackillop, Lucy, Simpson, Nigel, Waugh, Jason, Anumba, Dilly, Kenny, Louise C, Redman, Christopher W.G, Shennan, Andrew H

“…BACKGROUND—Hypertensive disorders of pregnancy are a major contributor to death and disability for pregnant women and their infants. The diagnosis of…”
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Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency by Mao, Jinyuan, Pop, Victor J, Bath, Sarah C, Vader, Huib L, Redman, Christopher W. G, Rayman, Margaret P

“…PURPOSE: Selenium is an essential trace mineral and a component of selenoproteins that are involved in the production of thyroid hormones and in regulating the…”
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Latest Advances in Understanding Preeclampsia by Redman, Christopher W, Sargent, Ian L

“…Preeclampsia is a relatively common pregnancy disorder that originates in the placenta and causes variable maternal and fetal problems. In the worst cases, it…”
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Redefining Preeclampsia Using Placenta-Derived Biomarkers by Staff, Anne Cathrine, Benton, Samantha J, von Dadelszen, Peter, Roberts, James M, Taylor, Robert N, Powers, Robert W, Charnock-Jones, D Stephen, Redman, Christopher W.G

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Effect of selenium on markers of risk of pre-eclampsia in UK pregnant women: a randomised, controlled pilot trial by RAYMAN, Margaret P, SEARLE, Elizabeth, KELLY, Lynne, JOHNSEN, Sigurd, BODMAN-SMITH, Katherine, BATH, Sarah C, JINYUAN MAO, REDMAN, Christopher W. G

“…Pre-eclampsia is a serious hypertensive condition of pregnancy associated with high maternal and fetal morbidity and mortality. Se intake or status has been…”
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Selenium in reproductive health by Mistry, Hiten D., PhD, Broughton Pipkin, Fiona, DPhil, FRCOG ad eundem, Redman, Christopher W.G., MD, FCRP, FRCOG, Poston, Lucilla, PhD, FRCOG ad eundem

“…Selenium is an essential trace element of importance to human biology and health. Increasing evidence suggests that this mineral plays an important role in…”
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Multicolor Flow Cytometry and Nanoparticle Tracking Analysis of Extracellular Vesicles in the Plasma of Normal Pregnant and Pre-eclamptic Women by DRAGOVIC, Rebecca A, SOUTHCOMBE, Jennifer H, TANNETTA, Dionne S, REDMAN, Christopher W. G, SARGENT, Ian L

“…Excessive release of syncytiotrophoblast extracellular vesicles (STBMs) from the placenta into the maternal circulation may contribute to the systemic…”
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Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin by Tannetta, Dionne S, Dragovic, Rebecca A, Gardiner, Chris, Redman, Christopher W, Sargent, Ian L

“…The placental syncytiotrophoblast releases micro and nanovesicles (STBM), into the maternal circulation in normal pregnancy and in increased amounts in…”
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Immunology of pre-eclampsia by Redman, Christopher W G, Sargent, Ian L

“…Pre-eclampsia develops in stages, only the last being the clinical illness. This is generated by a non-specific, systemic (vascular), inflammatory response,…”
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Systemic Inflammatory Priming in Normal Pregnancy and Preeclampsia: The Role of Circulating Syncytiotrophoblast Microparticles by Germain, Sarah J, Sacks, Gavin P, Soorana, Suren R, Sargent, Ian L, Redman, Christopher W

“…Systemic inflammatory responsiveness was studied in normal human pregnancy and its specific inflammatory disorder, pre-eclampsia. Compared with nonpregnancy,…”
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Maternal placental growth factor and soluble fms-like tyrosine kinase-1 reference ranges in post-term pregnancies: A prospective observational study by Mitlid-Mork, Birgitte, Bowe, Sophie, Gran, Jon M, Bolstad, Nils, Berg, Jens Petter, Redman, Christopher W, Staff, Anne Cathrine, Sugulle, Meryam

“…Post-term pregnancies have increased risks for adverse fetal and maternal outcomes. Maternal concentrations of the placenta-associated proteins placental…”
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Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity by Gardiner, Chris, Tannetta, Dionne S, Simms, Carol A, Harrison, Paul, Redman, Christopher W G, Sargent, Ian L

“…Pre-eclampsia is a complication of pregnancy associated with activation of coagulation. It is caused by the placenta, which sheds increased amounts of…”
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Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis by Dragovic, Rebecca A., MSc, Gardiner, Christopher, PhD, Brooks, Alexandra S., MD, Tannetta, Dionne S., PhD, Ferguson, David J.P., PhD, Hole, Patrick, PhD, Carr, Bob, PhD, Redman, Christopher W.G., MD, FRCP, Harris, Adrian L., MD, PhD, FRCP, Dobson, Peter J., PhD, FInstP, CPhys, Harrison, Paul, PhD, Sargent, Ian L., PhD

“…Abstract Cellular microvesicles and nanovesicles (exosomes) are involved in many disease processes and have major potential as biomarkers. However,…”
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Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function by Tannetta, Dionne S, Hunt, Kathryn, Jones, Chris I, Davidson, Naomi, Coxon, Carmen H, Ferguson, David, Redman, Christopher W, Gibbins, Jonathan M, Sargent, Ian L, Tucker, Katherine L

“…Pre-eclampsia (PE) complicates around 3% of all pregnancies and is one of the most common causes of maternal mortality worldwide. The pathophysiology of PE…”
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Maternal circulating levels of activin A, inhibin A, sFlt-1 and endoglin at parturition in normal pregnancy and pre-eclampsia by Reddy, Aparna, Suri, Sangeeta, Sargent, Ian L, Redman, Christopher W G, Muttukrishna, Shanthi

“…Maternal circulating levels of anti-angiogenic factors such as soluble fms-like tyrosine kinase-1 (sFlt-1), endoglin (sEng) and placental proteins like activin…”
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ST2 and IL-33 in pregnancy and pre-eclampsia by Granne, Ingrid, Southcombe, Jennifer H, Snider, James V, Tannetta, Dionne S, Child, Tim, Redman, Christopher W G, Sargent, Ian L

“…Normal pregnancy is associated with a mild systemic inflammatory response and an immune bias towards type 2 cytokine production, whereas pre-eclampsia is…”
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Measurement of refractive index by nanoparticle tracking analysis reveals heterogeneity in extracellular vesicles by Gardiner, Chris, Shaw, Michael, Hole, Patrick, Smith, Jonathan, Tannetta, Dionne, Redman, Christopher W., Sargent, Ian L.

“…Optical techniques are routinely used to size and count extracellular vesicles (EV). For comparison of data from different methods and laboratories, suitable…”
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Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system by Dunn, Warwick B., Broadhurst, David, Brown, Marie, Baker, Philip N., Redman, Christopher W.G., Kenny, Louise C., Kell, Douglas B.

“…Advances in analytical instrumentation can provide significant advantages to the volume and quality of biological knowledge acquired in metabolomic…”
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Multimodal Convolutional Neural Networks to Detect Fetal Compromise During Labor and Delivery by Petrozziello, Alessio, Redman, Christopher W. G., Papageorghiou, Aris T., Jordanov, Ivan, Georgieva, Antoniya

“…The gold standard to assess whether a baby is at risk of oxygen deprivation during childbirth, is monitoring continuously the fetal heart rate with…”
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