Search Results - "Redman, CWG"

Activin A and inhibin A as possible endocrine markers for pre-eclampsia by Muttukrishna, S, Knight, P G, Groome, N P, Redman, C W, Ledger, W L

“…Inhibin A and activin A are produced by the placenta during human pregnancy. This study aimed to measure circulating concentrations of inhibin A, pro alpha…”
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Diagnostic and predictive accuracy of placental growth factor in suspected pre-eclampsia by Redman, CWG

“…The diagnosis of preeclampsia can be difficult with considerable uncertainty when the presenting features are borderline. Moreover underlying medical…”
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Pre-eclampsia: A complex and variable disease by Redman, CWG

“…We would like to know the cause of pre-eclampsia. We would also like to be able to diagnose and treat it quickly and effectively, to be able to predict it…”
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The six stages of pre-eclampsia by Redman, CWG

“…For many years pre eclampsia has been considered to be a two-stage disease. The first stage comprises poor placentation. The second stage is the clinical…”
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Interleukin‐1 family cytokines and their regulatory proteins in normal pregnancy and pre‐eclampsia by Southcombe, J. H., Redman, C. W. G., Sargent, I. L., Granne, I.

“…Summary Maternal systemic inflammation is a feature of pre‐eclampsia, a condition in pregnancy characterized by hypertension and proteinuria. Pre‐eclampsia is…”
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Phase‐rectified signal averaging for intrapartum electronic fetal heart rate monitoring is related to acidaemia at birth by Georgieva, A, Papageorghiou, AT, Payne, SJ, Moulden, M, Redman, CWG

“…Objective Recent studies suggest that phase‐rectified signal averaging (PRSA), measured in antepartum fetal heart rate (FHR) traces, may sensitively indicate…”
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COLLECT, a collaborative database for pregnancy and placental research studies worldwide by Myers, JE, Myatt, L, Roberts, JM, Redman, CWG

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Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success by Hiby, Susan E, Walker, James J, O'shaughnessy, Kevin M, Redman, Christopher W G, Carrington, Mary, Trowsdale, John, Moffett, Ashley

“…Preeclampsia is a serious complication of pregnancy in which the fetus receives an inadequate supply of blood due to failure of trophoblast invasion. There is…”
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NK cells and human pregnancy – an inflammatory view by Sargent, Ian L., Borzychowski, Angela M., Redman, Christopher W.G.

“…For several years, reproductive immunology has been dominated by the ‘Th1/Th2’ hypothesis, in which the fetus avoids maternal T-cell rejection through a bias…”
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Pre-eclampsia, the Placenta and the Maternal Systemic Inflammatory Response—A Review by Redman, C.W.G., Sargent, I.L.

“…The central role of the placenta in the pathogenesis of pre-eclampsia is undisputed. The evidence that maternal syndrome of pre-eclampsia is caused by a…”
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Excess syncytiotrophoblast microparticle shedding is a feature of early-onset pre-eclampsia, but not normotensive intrauterine growth restriction by Goswami, D., Tannetta, D.S., Magee, L.A., Fuchisawa, A., Redman, C.W.G., Sargent, I.L., von Dadelszen, P.

“…Syncytiotrophoblast microparticles (STBM) are shed into the maternal circulation in higher amounts in pre-eclampsia compared to normal pregnancy and are…”
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Diagnostic accuracy of placental growth factor and ultrasound parameters to predict the small‐for‐gestational‐age infant in women presenting with reduced symphysis–fundus height by Griffin, M., Seed, P. T., Webster, L., Myers, J., MacKillop, L., Simpson, N., Anumba, D., Khalil, A., Denbow, M., Sau, A., Hinshaw, K., von Dadelszen, P., Benton, S., Girling, J., Redman, C. W. G., Chappell, L. C., Shennan, A. H.

“…Objectives To assess the diagnostic accuracy of placental growth factor (PlGF) and ultrasound parameters to predict delivery of a small‐for‐gestational‐age…”
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Expression of inflammatory cytokines in placentas from women with preeclampsia by Benyo, D F, Smarason, A, Redman, C W, Sims, C, Conrad, K P

“…It is postulated that inadequate remodeling of the uterine spiral arteries in preeclampsia leads to focal ischemia and generation of inflammatory cytokines,…”
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Preeclampsia: An excessive maternal inflammatory response to pregnancy by Redman, Christopher W.G., Sacks, Gavin P., Sargent, Ian L.

“…The maternal syndrome of preeclampsia has previously been ascribed to generalized maternal endothelial cell dysfunction. In this review we suggest that the…”
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Changes in systemic type 1 and type 2 immunity in normal pregnancy and pre‐eclampsia may be mediated by natural killer cells by Borzychowski, Angela M., Croy, B. Anne, Chan, W. Ling, Redman, Christopher W. G., Sargent, Ian L.

“…A bias of T cell immunity towards type 2 (Th2) is thought to be critical for normal pregnancy. Pathological pregnancies, such as pre‐eclampsia, are…”
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Microparticles and immunomodulation in pregnancy and pre-eclampsia by Redman, C.W.G, Sargent, I.L

“…Abstract Cellular microparticles are ubiquitously shed from cell membranes or secreted as endocytic vesicles called exosomes. Shed microparticles are ≥100 nm…”
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The value of the short‐term fetal heart rate variation for timing the delivery of growth‐retarded fetuses by Serra, V, Moulden, M, Bellver, J, Redman, CWG

“…Objective  To assess the clinical value of the short‐term fetal heart rate variation (STV) for timing the delivery of severely growth‐retarded fetuses, many…”
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Preeclampsia and the systemic inflammatory response by Redman, Christopher W G, Sargent, Ian L

“…Normal pregnancy is associated with a systemic inflammatory response. The response is exacerbated in preeclampsia and can account for its clinical features…”
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A computer system for the numerical analysis of nonstress tests by Pardey, James, Moulden, Mary, Redman, Christopher W.G.

“…The development and clinical validation of a computer system for the numerical analysis of nonstress tests is reviewed, and recent improvements are reported…”
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Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis by Sacks, Gavin P., Studena, Katarina, Sargent, Ian L., Redman, Christopher W.G.

“…OBJECTIVE: Our aim was to seek evidence for circulating leukocyte activation in preeclampsia. STUDY DESIGN: Whole blood flow cytometric techniques were used to…”
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