Search Results - "Redeuilh, Gérard"

Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers by Sabbah, Michèle, Emami, Shahin, Redeuilh, Gérard, Julien, Sylvia, Prévost, Grégoire, Zimber, Amazia, Ouelaa, Radia, Bracke, Marc, De Wever, Olivier, Gespach, Christian

“…Abstract The mechanisms involved in the epithelial to mesenchymal transition (EMT) are integrated in concert with master developmental and oncogenic pathways…”
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Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype by Ferrand, Nathalie, Gnanapragasam, Anne, Dorothee, Guillaume, Redeuilh, Gérard, Larsen, Annette K, Sabbah, Michèle

“…It has been proposed that the epithelial-mesenchymal transition (EMT) in mammary epithelial cells and breast cancer cells generates stem cell features. WISP2…”
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Molecular and pathological signatures of epithelial–mesenchymal transitions at the cancer invasion front by De Wever, Olivier, Pauwels, Patrick, De Craene, Bram, Sabbah, Michèle, Emami, Shahin, Redeuilh, Gérard, Gespach, Christian, Bracke, Marc, Berx, Geert

“…Reduction of epithelial cell–cell adhesion via the transcriptional repression of cadherins in combination with the acquisition of mesenchymal properties are…”
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CCN5, a Novel Transcriptional Repressor of the Transforming Growth Factor β Signaling Pathway by Sabbah, Michèle, Prunier, Céline, Ferrand, Nathalie, Megalophonos, Virginie, Lambein, Kathleen, De Wever, Olivier, Nazaret, Nicolas, Lachuer, Joël, Dumont, Sylvie, Redeuilh, Gérard

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Role of WISP-2/CCN5 in the Maintenance of a Differentiated and Noninvasive Phenotype in Human Breast Cancer Cells by Fritah, Asmaà, Saucier, Cécile, De Wever, Olivier, Bracke, Marc, Bièche, Ivan, Lidereau, Rosette, Gespach, Christian, Drouot, Sylvain, Redeuilh, Gérard, Sabbah, Michèle

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Glucocorticoids induce CCN5/WISP-2 expression and attenuate invasion in oestrogen receptor-negative human breast cancer cells by Ferrand, Nathalie, Stragier, Emilien, Redeuilh, Gérard, Sabbah, Michèle

“…CCN5 (cysteine-rich 61/connective tissue growth factor/nephroblastoma overexpressed 5)/WISP-2 [WNT1 (wingless-type MMTV integration site family, member…”
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Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3): and vascular endothelial growth factor-mediated cellular invasion and tumor growth by RIVAT, Christine, RODRIGUES, Sylvie, BRUYNEEL, Erik, PIETU, Geneviève, ROBERT, Amélie, REDEUILH, Gérard, BRACKE, Marc, GESPACH, Christian, ATTOUB, Samir

“…Signal transducer and activator of transcription (STAT) 3 is overexpressed or activated in most types of human tumors and has been classified as an oncogene…”
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Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells by Gaben, Anne-Marie, Sabbah, Michèle, Redeuilh, Gérard, Bedin, Monique, Mester, Jan

“…Ligand-dependent activation of the estrogen receptor (ER) as well as of the insulin-like growth factor type 1 (IGF1R) induces the proliferation of luminal…”
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Molecular cloning and characterization of the human WISP-2/CCN5 gene promoter reveal its upregulation by oestrogens by Fritah, Asmaà, Redeuilh, Gérard, Sabbah, Michèle

“…Wnt-1-induced signalling pathway protein-2 (WISP-2)/connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN)5 is a member of the CCN…”
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Synergistic cooperation between the AP‐1 and LEF‐1 transcription factors in the activation of the matrilysin promoter by the src oncogene: implications in cellular invasion by Rivat, Christine, Le Floch, Nathalie, Sabbah, Michèle, Teyrol, Isabelle, Redeuilh, Gérard, Bruyneel, Erik, Mareel, Marc, Matrisian, Lynn M., Crawford, Howard C., Gespach, Christian, Attoub, Samir

“…ABSTRACT The matrix metalloprotease matrilysin is expressed in premalignant polyps and plays a key role in local invasion during the progression of digestive…”
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Mitogenic Activity of Estrogens in Human Breast Cancer Cells Does Not Rely on Direct Induction of Mitogen-Activated Protein Kinase/Extracellularly Regulated Kinase or Phosphatidylinositol 3-Kinase by Gaben, Anne-Marie, Saucier, Cécile, Bedin, Monique, Redeuilh, Gérard, Mester, Jan

“…We have addressed the question of rapid, nongenomic mechanisms that may be involved in the mitogenic action of estrogens in hormone-dependent breast cancer…”
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Cell Cycle Arrest in G2 Induces Human Immunodeficiency Virus Type 1 Transcriptional Activation through Histone Acetylation and Recruitment of CBP, NF-κB, and c-Jun to the Long Terminal Repeat Promoter by THIERRY, Sylvain, MARECHAL, Vincent, ROSENZWAJG, Michelle, SABBAH, Michèle, REDEUILH, Gérard, NICOLAS, Jean-Claude, GOZLAN, Joël

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Transcriptional activation by the oestrogen receptor α is modulated through inhibition of cyclin-dependent kinases by REDEUILH, Gérard, ATTIA, Annette, MESTER, Jan, SABBAH, Michèle

“…We have investigated the interaction between the expression of p21(WAF1/CIP1/SDI1), a stoichiometric inhibitor of Cdk, and the transcriptional activity of the…”
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Human B-ind1 gene promoter: Cloning and regulation by histone deacetylase inhibitors by Sabbah, Michèle, Saucier, Cécile, Redeuilh, Gérard

“…Histone deacetylase inhibitors (HDIs) induced expression of the B-ind1 protein that is a component of Rac-1-signaling pathways leading to the modulation of…”
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Direct Inhibition of the Expression of Cyclin D1 Gene by Sodium Butyrate by Lallemand, François, Courilleau, Delphine, Sabbah, Michèle, Redeuilh, Gérard, Mester, Jan

“…In the mouse fibroblasts BP-A31 as well as in the human epidermoid carcinoma cells KB-3-1, both cyclin D1 mRNA and protein contents decreased rapidly during…”
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p21WAF1/CIP1 Selectively Controls the Transcriptional Activity of Estrogen Receptor α by Fritah, Asmaà, Saucier, Cécile, Mester, Jan, Redeuilh, Gérard, Sabbah, Michèle

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Estrogen Induction of the Cyclin D1 Promoter: Involvement of a cAMP Response-Like Element by Sabbah, M, Courilleau, D, Mester, J, Redeuilh, G

“…Estrogens induce cell proliferation in target tissues by stimulating progression through the G1phase of the cell cycle. Induction of cyclin D1 expression is a…”
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B-ind1, a Novel Mediator of Rac1 Signaling Cloned from Sodium Butyrate-treated Fibroblasts by Courilleau, Delphine, Chastre, Eric, Sabbah, Michèle, Redeuilh, Gérard, Atfi, Azeddine, Mester, Jan

“…Sodium butyrate is a multifunctional agent known to inhibit cell proliferation and to induce differentiation by modulating transcription. We have performed…”
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Cellular effects of purvalanol A: A specific inhibitor of cyclin‐dependent kinase activities by Villerbu, Nathalie, Gaben, Anne‐Marie, Redeuilh, Gérard, Mester, Jan

“…We have studied the effects of purvalanol A on the cell cycle progression, proliferation and viability. In synchronized cells, purvalanol A induced a…”
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Cell Cycle Arrest in G 2 Induces Human Immunodeficiency Virus Type 1 Transcriptional Activation through Histone Acetylation and Recruitment of CBP, NF-κB, and c-Jun to the Long Terminal Repeat Promoter by Thierry, Sylvain, Marechal, Vincent, Rosenzwajg, Michelle, Sabbah, Michèle, Redeuilh, Gérard, Nicolas, Jean-Claude, Gozlan, Joël

“…In human immunodeficiency virus type 1 (HIV-1)-infected cells, a cell cycle arrest in G 2 increases viral expression and may represent a strategy for the virus…”
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