Search Results - "Reder, Anthony T."

Clostridium epsilon toxin is excessive in multiple sclerosis and provokes multifocal lesions in mouse models by Reder, Anthony T

“…Multiple sclerosis (MS) is an inflammatory disease of the CNS. In this issue of the JCI, Ma and Sannino et al. show that two strains of intestinal Clostridium…”
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Vitamin D and Multiple Sclerosis: A Comprehensive Review by Sintzel, Martina B., Rametta, Mark, Reder, Anthony T.

“…Numerous observational studies have suggested that there is a correlation between the level of serum vitamin D and MS risk and disease activity. To explore…”
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Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomised, placebo-controlled, phase 3 trial by Calabresi, Peter A, Dr, Radue, Ernst-Wilhelm, Prof, Goodin, Douglas, MD, Jeffery, Douglas, MD, Rammohan, Kottil W, MD, Reder, Anthony T, MD, Vollmer, Timothy, MD, Agius, Mark A, MD, Kappos, Ludwig, Prof, Stites, Tracy, PhD, Li, Bingbing, PhD, Cappiello, Linda, MD, von Rosenstiel, Philipp, MD, Lublin, Fred D, MD

“…Summary Background Fingolimod has shown reductions in clinical and MRI disease activity in patients with relapsing-remitting multiple sclerosis. We further…”
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Prolonged Interferon-Stimulated Gene and Protein Signatures in Multiple Sclerosis Induced by PEGylated IFN-β-1a Compared to Non-PEGylated IFN-β-1a by Nguyen, Kristi, Olcer, Maya, Howlett-Prieto, Quentin, Feng, Xuan, Reder, Anthony T

“…Interferon (IFN)-β-1a (Avonex) and longer half-life, polyethylene glycol-conjugated IFN-β-1a (PEG-IFN-β-1a, Plegridy), may generate different molecular…”
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How type I interferons work in multiple sclerosis and other diseases: some unexpected mechanisms by Reder, Anthony T, Feng, Xuan

“…Type I interferons (IFNs) are important in innate and adaptive immunity. They are used to treat virus infections, cancer, and multiple sclerosis (MS). There…”
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Ophthalmic Evaluations in Clinical Studies of Fingolimod (FTY720) in Multiple Sclerosis by Zarbin, Marco A., MD, PhD, Jampol, Lee M., MD, Jager, Rama D., MD, MBA, Reder, Anthony T., MD, Francis, Gordon, MD, Collins, William, MD, Tang, Dejun, PhD, Zhang, Xiaoli, MD

“…Purpose To report outcomes of ophthalmic evaluations in clinical studies of patients receiving fingolimod (Gilenya; Novartis Pharma AG, Basel, Switzerland) for…”
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Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial by Voskuhl, Rhonda R, Prof, Wang, HeJing, MD, Wu, T C Jackson, MD, Sicotte, Nancy L, MD, Nakamura, Kunio, PhD, Kurth, Florian, PhD, Itoh, Noriko, MS, Bardens, Jenny, RN, Bernard, Jacqueline T, MD, Corboy, John R, Prof, Cross, Anne H, Prof, Dhib-Jalbut, Suhayl, Prof, Ford, Corey C, Prof, Frohman, Elliot M, Prof, Giesser, Barbara, Prof, Jacobs, Dina, MD, Kasper, Lloyd H, Prof, Lynch, Sharon, Prof, Parry, Gareth, Prof, Racke, Michael K, Prof, Reder, Anthony T, Prof, Rose, John, Prof, Wingerchuk, Dean M, Prof, MacKenzie-Graham, Allan J, PhD, Arnold, Douglas L, Prof, Tseng, Chi Hong, PhD, Elashoff, Robert, Prof

“…Summary Background Relapses of multiple sclerosis decrease during pregnancy, when the hormone estriol is increased. Estriol treatment is anti-inflammatory and…”
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Interferon-β corrects massive gene dysregulation in multiple sclerosis: Short-term and long-term effects on immune regulation and neuroprotection by Feng, Xuan, Bao, Riyue, Li, Lei, Deisenhammer, Florian, Arnason, Barry G.W., Reder, Anthony T.

“…In multiple sclerosis (MS), immune up-regulation is coupled to subnormal immune response to interferon-β (IFN-β) and low serum IFN-β levels. The relationship…”
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Immunomodulatory activity of interferon‐beta by Kasper, Lloyd H., Reder, Anthony T.

“…Multiple sclerosis (MS) is a complex disorder of the central nervous system that appears to be driven by a shift in immune functioning toward excess…”
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Understanding humoral immunity and multiple sclerosis severity in Black, and Latinx patients by Telesford, Kiel M, Amezcua, Lilyana, Tardo, Lauren, Horton, Lindsay, Lund, Brett T, Reder, Anthony T, Vartanian, Timothy, Monson, Nancy L

“…People identified with Black/African American or Hispanic/Latinx ethnicity are more likely to exhibit a more severe multiple sclerosis disease course relative…”
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Adaptive and innate immune responses in multiple sclerosis with anti-CD20 therapy: Gene expression and protein profiles by Fong, Chloe C, Spencer, Julian, Howlett-Prieto, Quentin, Feng, Xuan, Reder, Anthony T

“…Anti-CD20 is a highly effective therapy for multiple sclerosis (MS), a disease with multiple abnormalities in function of B and T cells and innate immune…”
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Corrigendum: Adaptive and innate immune responses in multiple sclerosis with anti-CD20 therapy: gene expression and protein profiles by Fong, Chloe C., Spencer, Julian, Howlett-Prieto, Quentin, Feng, Xuan, Reder, Anthony T.

“…[This corrects the article DOI: 10.3389/fneur.2023.1158487.]…”
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Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis by Polman, Chris H, Prof, Bertolotto, Antonio, MD, Deisenhammer, Florian, Prof, Giovannoni, Gavin, Prof, Hartung, Hans-Peter, Prof, Hemmer, Bernhard, Prof, Killestein, Joep, MD, McFarland, Henry F, MD, Oger, Joel, Prof, Pachner, Andrew R, Prof, Petkau, John, Prof, Reder, Anthony T, MD, Reingold, Stephen C, PhD, Schellekens, Huub, Prof, Sørensen, Per Soelberg, Prof

“…Summary The identification of factors that can affect the efficacy of immunomodulatory drugs in relapsing-remitting multiple sclerosis (MS) is important. For…”
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Gray matter atrophy in multiple sclerosis despite clinical and lesion stability during natalizumab treatment by Koskimäki, Fredrika, Bernard, Jacqueline, Yong, Jeong, Arndt, Nancy, Carroll, Timothy, Lee, Seon-Kyu, Reder, Anthony T, Javed, Adil

“…Brain volume loss is an important surrogate marker for assessing disability in MS; however, contribution of gray and white matter to the whole brain volume…”
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Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology by Reder, Anthony T, Feng, Xuan

“…Studying the action of mechanisms of type I interferon (IFN) provides the insight to elucidate the cause and therapy for autoimmune diseases. There are high…”
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Validity of the Neurology Quality-of-Life (Neuro-QoL) measurement system in adult epilepsy by Victorson, David, Cavazos, Jose E, Holmes, Gregory L, Reder, Anthony T, Wojna, Valerie, Nowinski, Cindy, Miller, Deborah, Buono, Sarah, Mueller, Allison, Moy, Claudia, Cella, David

“…Abstract Epilepsy is a chronic neurological disorder that results in recurring seizures and can have a significant adverse effect on health-related quality of…”
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Twenty Years of Subcutaneous Interferon-Beta-1a for Multiple Sclerosis: Contemporary Perspectives by Freedman, Mark S., Coyle, Patricia K., Hellwig, Kerstin, Singer, Barry, Wynn, Daniel, Weinstock-Guttman, Bianca, Markovic-Plese, Silva, Galazka, Andrew, Dangond, Fernando, Korich, Julie, Reder, Anthony T.

“…Multiple sclerosis (MS) is a chronic, progressive, inflammatory disorder of the central nervous system. Relapsing–remitting MS (RRMS), the most common form of…”
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Therapeutic role of beta-interferons in multiple sclerosis by Javed, Adil, Reder, Anthony T

“…Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). In the last 12 years, there has been a proliferation of studies…”
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Establishing long-term efficacy in chronic disease: use of recursive partitioning and propensity score adjustment to estimate outcome in MS by Goodin, Douglas S, Jones, Jason, Li, David, Traboulsee, Anthony, Reder, Anthony T, Beckmann, Karola, Konieczny, Andreas, Knappertz, Volker

“…Establishing the long-term benefit of therapy in chronic diseases has been challenging. Long-term studies require non-randomized designs and, thus, are often…”
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Thoracic flexion provokes circumferential dysesthesia: A symptom of thoracic cord lesions in MS by Reder, Anthony T

“…Thoracic flexion, a rapid forward flexion at the waist, can elicit a circumferential electrical sensation in some patients with multiple sclerosis. The…”
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