Search Results - "Redemann, Stefanie"

Mitotic spindles revisited - new insights from 3D electron microscopy by Müller-Reichert, Thomas, Kiewisz, Robert, Redemann, Stefanie

“…The mitotic spindle is a complex three-dimensional (3D) apparatus that functions to ensure the faithful segregation of chromosomes during cell division. Our…”
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C. elegans chromosomes connect to centrosomes by anchoring into the spindle network by Redemann, Stefanie, Baumgart, Johannes, Lindow, Norbert, Shelley, Michael, Nazockdast, Ehssan, Kratz, Andrea, Prohaska, Steffen, Brugués, Jan, Fürthauer, Sebastian, Müller-Reichert, Thomas

“…The mitotic spindle ensures the faithful segregation of chromosomes. Here we combine the first large-scale serial electron tomography of whole mitotic spindles…”
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Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth by Mauro, Michael Sean, Celma, Gunta, Zimyanin, Vitaly, Magaj, Magdalena M, Gibson, Kimberley H, Redemann, Stefanie, Bahmanyar, Shirin

“…The nuclear envelope (NE) assembles and grows from bilayer lipids produced at the endoplasmic reticulum (ER). How ER membrane incorporation coordinates with…”
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Central-spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B by Yu, Che-Hang, Redemann, Stefanie, Wu, Hai-Yin, Kiewisz, Robert, Yoo, Tae Yeon, Conway, William, Farhadifar, Reza, Müller-Reichert, Thomas, Needleman, Daniel

“…Spindle microtubules, whose dynamics vary over time and at different locations, cooperatively drive chromosome segregation. Measurements of microtubule…”
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The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth by Chaaban, Sami, Jariwala, Shashank, Hsu, Chieh-Ting, Redemann, Stefanie, Kollman, Justin M., Müller-Reichert, Thomas, Sept, David, Bui, Khanh Huy, Brouhard, Gary J.

“…The dynamic instability of microtubules is a conserved and fundamental mechanism in eukaryotes. Yet microtubules from different species diverge in their growth…”
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Codon adaptation-based control of protein expression in C. elegans by Bringmann, Henrik, Redemann, Stefanie, Schloissnig, Siegfried, Ernst, Susanne, Pozniakowsky, Andrey, Ayloo, Swathi, Hyman, Antony A

“…We present a method to control protein levels under native genetic regulation in Caenorhabditis elegans by using synthetic genes with adapted codons. We found…”
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iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse by Zhao, Xiao-Yu, Lempke, Samantha L., Urbán Arroyo, Jan C., Brown, Isabel G., Yin, Bocheng, Magaj, Magdalena M., Holness, Nadia K., Smiley, Jamison, Redemann, Stefanie, Ewald, Sarah E.

“…Toxoplasma gondii is an obligate intracellular parasite of rodents and humans. Interferon-inducible guanylate binding proteins (GBPs) are mediators of T…”
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Microtubule reorganization during female meiosis in C. elegans by Lantzsch, Ina, Yu, Che-Hang, Chen, Yu-Zen, Zimyanin, Vitaly, Yazdkhasti, Hossein, Lindow, Norbert, Szentgyoergyi, Erik, Pani, Ariel M, Prohaska, Steffen, Srayko, Martin, Fürthauer, Sebastian, Redemann, Stefanie

“…Most female meiotic spindles undergo striking morphological changes while transitioning from metaphase to anaphase. The ultra-structure of meiotic spindles,…”
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Correction: Microtubule reorganization during female meiosis in C. elegans by Lantzsch, Ina, Yu, Che-Hang, Chen, Yu-Zen, Zimyanin, Vitaly, Yazdkhasti, Hossein, Lindow, Norbert, Szentgyoergyi, Erik, Pani, Ariel M, Prohaska, Steffen, Srayko, Martin, Fürthauer, Sebastian, Redemann, Stefanie

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Editorial: Mechanics of Cell Division by Shimamoto, Yuta, Redemann, Stefanie, Needleman, Daniel

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Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos by Redemann, Stefanie, Pecreaux, Jacques, Goehring, Nathan W, Khairy, Khaled, Stelzer, Ernst H K, Hyman, Anthony A, Howard, Jonathon

“…Asymmetric positioning of the mitotic spindle in C. elegans embryos is mediated by force-generating complexes that are anchored at the plasma membrane and that…”
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Correlative light and electron microscopy for the analysis of cell division by REDEMANN, STEFANIE, MÜLLER‐REICHERT, THOMAS

“…Summary Correlative light and electron microscopy (CLEM) has recently gained increasing attention, because it enables the acquisition of dynamic as well as…”
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Live Cell Imaging of ATP Levels Reveals Metabolic Compartmentalization within Motoneurons and Early Metabolic Changes in FUS ALS Motoneurons by Zimyanin, Vitaly L, Pielka, Anna-Maria, Glaß, Hannes, Japtok, Julia, Großmann, Dajana, Martin, Melanie, Deussen, Andreas, Szewczyk, Barbara, Deppmann, Chris, Zunder, Eli, Andersen, Peter M, Boeckers, Tobias M, Sterneckert, Jared, Redemann, Stefanie, Storch, Alexander, Hermann, Andreas

“…Motoneurons are one of the most energy-demanding cell types and a primary target in Amyotrophic lateral sclerosis (ALS), a debilitating and lethal…”
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The segmentation of microtubules in electron tomograms using Amira by Redemann, Stefanie, Weber, Britta, Möller, Marit, Verbavatz, Jean-Marc, Hyman, Anthony A, Baum, Daniel, Prohaska, Steffen, Müller-Reichert, Thomas

“…The development of automatic tools for the three-dimensional reconstruction of the microtubule cytoskeleton is crucial for large-scale analysis of mitotic…”
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Microtubule length correlates with spindle length in C. elegans meiosis by Zimyanin, Vitaly, Redemann, Stefanie

“…The accurate segregation of chromosomes during female meiosis relies on the precise assembly and function of the meiotic spindle, a dynamic structure primarily…”
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Mechanics of the spindle apparatus by Nazockdast, Ehssan, Redemann, Stefanie

“…During mitosis microtubules self-organize to form a bipolar mitotic spindle structure, which positions the sister chromatids on the spindle mid-plane and…”
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Cell scientist to watch – Stefanie Redemann

“…ABSTRACT Stefanie Redemann studied Biology at Darmstadt Technical University, followed by a Master's at EMBL in Heidelberg, Germany. She then pursued a PhD in…”
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The fission yeast MO25 protein functions in polar growth and cell separation by Mendoza, Manuel, Redemann, Stefanie, Brunner, Damian

“…Proteins of the MO25 family are widely conserved but their function has not been characterized in detail. Human MO25 is a cofactor of LKB1, a conserved protein…”
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Integrated 3D Tomography and Computational Modeling to Study Forces in Metaphase Spindles by Redemann, Stefanie, Nazockdast, Ehssan

“…Abstract only Chromosome segregation during mitosis and meiosis are fundamental processes of life. During its course a bipolar spindle assembles and initially…”
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The role of the spindle midzone during chromosome segregation by Redemann, Stefanie, Yu, Che‐Hang, Horton, Xavier, Needleman, Daniel

“…The faithful segregation of chromosomes during mitosis is essential for the health and survival of any eukaryotic organisms. Any failure in this process has…”
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