Search Results - "Redelinghuys, Pierre"
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Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells
Published in PLoS biology (01-09-2013)“…Intestinal microfold (M) cells possess a high transcytosis capacity and are able to transport a broad range of materials including particulate antigens,…”
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2
Siglecs as positive and negative regulators of the immune system
Published in Biochemical Society transactions (01-12-2008)“…Siglecs (sialic acid-binding Ig-like lectins) are mainly expressed in the immune system. Sn (sialoadhesin) (siglec-1), CD22 (siglec-2) and siglec-15 are well…”
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3
Inhibitory C-type lectin receptors in myeloid cells
Published in Immunology letters (30-04-2011)“…Abstract C-type lectin receptors encoded by the natural killer gene complex play critical roles in enabling NK cell discrimination between self and non-self…”
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4
Dectin-1 Is Not Required for Controlling Candida albicans Colonization of the Gastrointestinal Tract
Published in Infection and Immunity (01-12-2012)“…OA Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma
Published in PloS one (11-08-2015)“…Asthma is a heterogeneous disease whose etiology is poorly understood but is likely to involve innate responses to inhaled microbial components that are found…”
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6
Characterisation of innate fungal recognition in the lung
Published in PloS one (20-04-2012)“…The innate recognition of fungi by leukocytes is mediated by pattern recognition receptors (PRR), such as Dectin-1, and is thought to occur at the cell surface…”
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7
Correction: Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma
Published in PloS one (08-09-2015)Get full text
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8
The N Domain of Human Angiotensin-I-converting Enzyme
Published in The Journal of biological chemistry (01-11-2010)“…Angiotensin-I-converting enzyme (ACE) plays a critical role in the regulation of blood pressure through its central role in the renin-angiotensin and…”
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9
Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme
Published in Biochemical journal (15-04-2003)“…Angiotensin I-converting enzyme (ACE) is a highly glycosylated type I integral membrane protein. A series of underglycosylated testicular ACE (tACE)…”
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10
Recognition and control of neutrophil extracellular trap formation by MICL
Published in Nature (London) (12-09-2024)“…Regulation of neutrophil activation is critical for disease control. Neutrophil extracellular traps (NETs), which are web-like structures composed of DNA and…”
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11
MICL controls inflammation in rheumatoid arthritis
Published in Annals of the rheumatic diseases (01-07-2016)“…Myeloid inhibitory C-type lectin-like receptor (MICL, Clec12A) is a C-type lectin receptor (CLR) expressed predominantly by myeloid cells. Previous studies…”
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N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407
Published in The Journal of biological chemistry (12-11-2010)“…Angiotensin-I-converting enzyme (ACE) plays a critical role in the regulation of blood pressure through its central role in the renin-angiotensin and…”
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13
β-Glucan exacerbates allergic airway responses to house dust mite allergen
Published in Respiratory research (02-04-2016)“…β-(1,3)-Glucan is present in mould cell walls and frequently detected in house dust mite (HDM) faeces. β-Glucan exposure is thought to be associated with…”
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14
Early Murine T-lymphocyte Activation Is Accompanied by a Switch from N-Glycolyl- to N-Acetyl-neuraminic Acid and Generation of Ligands for Siglec-E
Published in The Journal of biological chemistry (07-10-2011)“…It is well established that murine T-lymphocyte activation is accompanied by major changes in cell-surface sialylation, potentially influencing interactions…”
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15
Glucan exacerbates allergic airway responses to house dust mite allergen
Published in Respiratory research (02-04-2016)“…[beta]-(1,3)-Glucan is present in mould cell walls and frequently detected in house dust mite (HDM) faeces. [beta]-Glucan exposure is thought to be associated…”
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16
Dectin-1 Is Essential for Reverse Transcytosis of Glycosylated SIgA-Antigen Complexes by Intestinal M Cells: e1001658
Published in PLoS biology (01-09-2013)“…Intestinal microfold (M) cells possess a high transcytosis capacity and are able to transport a broad range of materials including particulate antigens,…”
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17
Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors
Published in Bioorganic & medicinal chemistry letters (01-09-2006)“…Novel analogues of the angiotensin I-converting enzyme (ACE) inhibitor keto-ACE were synthesized via a facile Horner–Emmons olefination of a phosphonoketone…”
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18
Synthesis and molecular modeling of a lisinopril–tryptophan analogue inhibitor of angiotensin I-converting enzyme
Published in Bioorganic & medicinal chemistry letters (01-09-2006)“…With a view to developing a more C-domain-selective angiotensin I-converting enzyme (ACE)-inhibitor, a novel analogue of lisinopril has been synthesized which…”
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19
The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme
Published in Biological chemistry (01-09-2008)“…The N and C domains of somatic angiotensin-converting enzyme (sACE) differ in terms of their substrate specificity, inhibitor profiling, chloride dependency…”
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Development of Domain-Selective Angiotensin I-Converting Enzyme Inhibitors
Published in Annals of the New York Academy of Sciences (01-11-2005)“…Somatic angiotensin‐converting enzyme (ACE) is an essential component of the renin‐angiotensin system and consequently plays a key role in blood pressure and…”
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