Search Results - "Redei, E. E."

Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models by Andrus, B M, Blizinsky, K, Vedell, P T, Dennis, K, Shukla, P K, Schaffer, D J, Radulovic, J, Churchill, G A, Redei, E E

“…The etiology of depression is still poorly understood, but two major causative hypotheses have been put forth: the monoamine deficiency and the stress…”
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Sex differences in depressive, anxious behaviors and hippocampal transcript levels in a genetic rat model by Mehta, N. S., Wang, L., Redei, E. E.

“…Major depressive disorder (MDD) is a common, debilitating illness with high prevalence of comorbid anxiety. The incidence of depression and of comorbid anxiety…”
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Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants by WILL, C. C, AIRD, F, REDEI, E. E

“…The Wistar-Kyoto (WKY) rat strain demonstrates endogenous hormonal and behavioral abnormalities that emulate many of those found in symptom-presenting…”
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Pilot validation of blood-based biomarkers during pregnancy and postpartum in women with prior or current depression by Redei, E. E., Ciolino, J. D., Wert, S. L., Yang, A., Kim, S., Clark, C., Zumpf, K. B., Wisner, K. L.

“…Major depressive disorder (MDD) is more common in women than in men, and evidence of gender-related subtypes of depression is emerging. Previously identified…”
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Hippocampus-dependent memory and allele-specific gene expression in adult offspring of alcohol-consuming dams after neonatal treatment with thyroxin or metformin by Tunc-Ozcan, E, Wert, S L, Lim, P H, Ferreira, A, Redei, E E

“…Fetal alcohol spectrum disorder (FASD), the result of fetal alcohol exposure (FAE), affects 2–11% of children worldwide, with no effective treatments…”
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The WMI Rat of Premature Cognitive Aging Presents Intrinsic Vulnerability to Oxidative Stress in Primary Neurons and Astrocytes Compared to Its Nearly Isogenic WLI Control by Ferreira, Adriana, Harter, Aspen, Afreen, Sana, Kanai, Karoly, Batori, Sandor, Redei, Eva E

“…The primary neuronal and astrocyte culture described here is from the stress-hyperreactive Wistar Kyoto (WKY) More Immobile (WMI) rat with premature…”
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The Wistar Kyoto Rat: A Model of Depression Traits by Redei, Eva E, Udell, Mallory E, Solberg Woods, Leah C, Chen, Hao

“…There is an ongoing debate about the value of animal research in psychiatry with valid lines of reasoning stating the limits of individual animal models…”
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Sex and heredity are determinants of drug intake in a novel model of rat oral oxycodone self‐administration by Sharp, Burt M., Fan, Xinyu, Redei, Eva E., Mulligan, Megan K., Chen, Hao

“…The steady rise in prescription opioids such as oxycodone has led to a virulent epidemic of widespread abuse and deaths in the United States; approximately 80%…”
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TailTimer: A device for automating data collection in the rodent tail immersion assay by Udell, Mallory E, Ni, Jie, Garcia Martinez, Angel, Mulligan, Megan K, Redei, Eva E, Chen, Hao

“…The tail immersion assay is a widely used method for measuring acute thermal pain in a way which is quantifiable and reproducible. It is non-invasive and…”
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Whole genome sequencing of nearly isogenic WMI and WLI inbred rats identifies genes potentially involved in depression and stress reactivity by de Jong, Tristan V., Kim, Panjun, Guryev, Victor, Mulligan, Megan K., Williams, Robert W., Redei, Eva E., Chen, Hao

“…The WMI and WLI inbred rats were generated from the stress-prone, and not yet fully inbred, Wistar Kyoto (WKY) strain. These were selected using bi-directional…”
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Blood transcriptomic markers for major depression: from animal models to clinical settings by Redei, Eva E., Mehta, Neha S.

“…Depression is a heterogeneous disorder and, similar to other spectrum disorders, its manifestation varies by age of onset, severity, comorbidity, treatment…”
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A support vector machine model provides an accurate transcript-level-based diagnostic for major depressive disorder by Yu, J S, Xue, A Y, Redei, E E, Bagheri, N

“…Major depressive disorder (MDD) is a critical cause of morbidity and disability with an economic cost of hundreds of billions of dollars each year,…”
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Sex-Specific Behavioral Response to Early Adolescent Stress in the Genetically More Stress-Reactive Wistar Kyoto More Immobile, and Its Nearly Isogenic Wistar Kyoto Less Immobile Control Strain by Kim, Sarah, Gacek, Stephanie A, Mocchi, Madaline M, Redei, Eva E

“…Genetic predisposition and environmental stress are known etiologies of stress-related psychiatric disorders. Environmental stress during adolescence is…”
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Reduced Hippocampal and Anterior Cingulate Expression of Antioxidant Enzymes and Membrane Progesterone Receptors in Alzheimer's Disease with Depression by Luo, Wendy, Pryzbyl, Katherine J, Bigio, Eileen H, Weintraub, Sandra, Mesulam, M-Marsel, Redei, Eva E

“…Major depressive disorder (MDD) is a risk factor for dementia including that caused by Alzheimer's disease (AD). Both MDD and AD have a higher prevalence in…”
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Genetic stress-reactivity, sex, and conditioning intensity affect stress-enhanced fear learning by Przybyl, K.J., Jenz, S.T., Lim, P.H., Ji, M.T., Wert, S.L., Luo, W., Gacek, S.A., Schaack, A.K., Redei, E.E.

“…•Stress-Enhanced Fear Learning and fear memory modified by genetic stress-sensitivity.•Stress-Enhanced Fear Learning and fear memory are highly…”
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Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy by Redei, E E, Andrus, B M, Kwasny, M J, Seok, J, Cai, X, Ho, J, Mohr, D C

“…An objective, laboratory-based diagnostic tool could increase the diagnostic accuracy of major depressive disorders (MDDs), identify factors that characterize…”
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Chronic stress from adolescence to adulthood increases adiposity and anxiety in rats with decreased expression of Krtcap3 by Szalanczy, Alexandria M, Fitzpatrick, Mackenzie, Beeson, Angela, Bui, Trangdai, Dyson, Christina, Eller, Seth, Landry, Julia, Scott, Christina, Grzybowski, Michael, Klotz, Jason, Geurts, Aron M, Weiner, Jeff L, Redei, Eva E, Solberg Woods, Leah C

“…We previously identified , , as a novel adiposity gene, but subsequently found that its impact on adiposity may depend on environmental stress. To more…”
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Heterogeneous stock rats: a model to study the genetics of despair‐like behavior in adolescence by Holl, K., He, H., Wedemeyer, M., Clopton, L., Wert, S., Meckes, J. K., Cheng, R., Kastner, A., Palmer, A. A., Redei, E. E., Solberg Woods, L. C.

“…Major depressive disorder (MDD) is a complex illness caused by both genetic and environmental factors. Antidepressant resistance also has a genetic component…”
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Brain region-specific expression of genes mapped within quantitative trait loci for behavioral responsiveness to acute stress in Fisher 344 and Wistar Kyoto male rats by Meckes, Jeanie K, Lim, Patrick H, Wert, Stephanie L, Luo, Wendy, Gacek, Stephanie A, Platt, Dana, Jankord, Ryan, Saar, Kathrin, Redei, Eva E

“…Acute stress responsiveness is a quantitative trait that varies in severity from one individual to another; however, the genetic component underlying the…”
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Hypothalamic Gene Expression and Postpartum Behavior in a Genetic Rat Model of Depression by Luo, Wendy, Lim, Patrick H., Wert, Stephanie L., Gacek, Stephanie A., Chen, Hao, Redei, Eva E.

“…Postpartum depression is a complex illness that often occurs in genetically predisposed individuals. Closely related inbred rat strains are a great resource to…”
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