Search Results - "Reddy, Thipparthi R."

Hsp22 (HspB8/H11) knockdown induces sam68 expression and stimulates proliferation of glioblastoma cells by Modem, Suhasini, Chinnakannu, Kannagi, Bai, Uma, Reddy, G. Prem-Veer, Reddy, Thipparthi R.

“…Sam68 (Src‐associated protein in mitosis 68 kDa) is a multifunctional protein, known to govern cellular signal transduction, transcription, RNA metabolism,…”
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Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K by Yang, Jian-Ping, Reddy, Thipparthi R, Truong, Ky T, Suhasini, Modem, Wong-Staal, Flossie

“…Sam68 is a target of the c-Src tyrosine kinase. We previously showed that overexpression of Sam68 functionally substitutes for, as well as synergies with,…”
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Cellular proteins and HIV-1 Rev function by Suhasini, Modem, Reddy, Thipparthi R

“…The human immunodeficiency virus (HIV-1) differentially controls viral protein expression at the level of splicing as well as nuclear export of incompletely…”
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An anti-apoptotic protein, Hax-1, inhibits the HIV-1 rev function by altering its sub-cellular localization by Modem, Suhasini, Reddy, Thipparthi R.

“…The human immunodeficiency virus type 1 (HIV‐1) Rev protein facilitates the nuclear export of viral mRNA containing the Rev response element (RRE). Although…”
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Fresh Garlic Extract Induces Growth Arrest and Morphological Differentiation of MCF7 Breast Cancer Cells by Modem, Suhasini, Dicarlo, Stephen E, Reddy, Thipparthi R

“…Consumption of diets rich in fruits and vegetables is often associated with a reduced risk of developing cancer, particularly breast cancer. Considering that 1…”
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Sam68 is absolutely required for Rev function and HIV-1 production by Modem, Suhasini, Badri, Kameswara R., Holland, Thomas C., Reddy, Thipparthi R.

“…Sam68 functionally complements for, as well as synergizes with, HIV-1 Rev in Rev response element (RRE)-mediated gene expression and virus production…”
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Retroviral Foxp3 gene transfer ameliorates liver granuloma pathology in Schistosoma mansoni infected mice by Singh, Kameshwar P., Gerard, Herve C., Hudson, Alan P., Reddy, Thipparthi R., Boros, Dov L.

“…Summary Schistosomiasis mansoni, a tropical helminthic disease, is caused by disseminated worm eggs that induce CD4+ T‐cell mediated granulomatous inflammation…”
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Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev by Reddy, Thipparthi R, Xu, Weidong, Mau, Jonathan K. L, Goodwin, Christopher D, Suhasini, Modem, Tang, Hengli, Frimpong, Kenneth, Rose, David W, Wong-Staal, Flossie

“…The HIV-1 Rev protein facilitates the nuclear export of mRNA containing the Rev response element (RRE) through binding to the export receptor CRM-1. Here we…”
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Regulation of Sam68 activity by small heat shock protein 22 by Badri, Kameswara R., Modem, Suhasini, Gerard, Herve C., Khan, Insia, Bagchi, Mihir, Hudson, Alan P., Reddy, Thipparthi R.

“…Sam68 associates with c‐Src kinase during mitosis. We previously demonstrated that Sam68 functionally replaces and/or synergizes with HIV‐1 Rev in rev response…”
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A Role for RNA Helicase A in Post-Transcriptional Regulation of HIV Type 1 by Li, Junzhou, Tang, Hengli, Mullen, Tina-Marie, Westberg, Christopher, Reddy, Thipparthi R., Rose, David W., Wong-Staal, Flossie

“…Retroviruses must bypass the tight coupling of splicing and nuclear export of mRNA in their replication cycle because unspliced genomic RNA and incompletely…”
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Sam68, RNA helicase A and Tap cooperate in the post-transcriptional regulation of human immunodeficiency virus and type D retroviral mRNA by REDDY, T. R, HENGLI TANG, WEIDONG XU, WONG-STAAL, F

“…Unlike cellular mRNA, retroviral mRNA bypasses the tight coupling of the splicing and nuclear export steps to allow the export of intron-containing viral RNA…”
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Sam68 is absolutely required for Rev function and HIV-1 production by Modem, Suhasini, Badri, Kameswara R., Holland, Thomas C., Reddy, Thipparthi R.

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Mapping the Functional Domains of HAP95, a Protein That Binds RNA Helicase A and Activates the Constitutive Transport Element of Type D Retroviruses by Yang, J P, Tang, H, Reddy, T R, Wong-Staal, F

“…The complex retroviruses such as human immunodeficiency virus, type 1, employ a virally encoded protein, Rev, to mediate the nuclear export of unspliced and…”
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General effect of Sam68 on Rev/Rex regulated expression of complex retroviruses by REDDY, T. R, XU, W.-D, WONG-STAAL, F

“…We have previously demonstrated that overexpression of Sam68 functionally substitutes for, as well as synergizes with, HIV-1 Rev in RRE-mediated gene…”
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Interactions of HIV-1 Nef with the μ Subunits of Adaptor Protein Complexes 1, 2, and 3: Role of the Dileucine-Based Sorting Motif by Craig, Heather M., Reddy, Thipparthi R., Riggs, Nanette L., Dao, Philip P., Guatelli, John C.

“…HIV-1 Nef interacts with cellular adaptor protein (AP) complexes and their medium (μ) subunits. However, the role of the dileucine-based sorting motif within…”
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