Search Results - "Reddy, Shantan G"

Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris by Ellebrecht, Christoph T., Mukherjee, Eric M., Zheng, Qi, Choi, Eun Jung, Reddy, Shantan G., Mao, Xuming, Payne, Aimee S.

“…Lineage analysis of autoreactive B cells can reveal the origins of autoimmunity. In the autoimmune disease pemphigus vulgaris (PV), desmoglein 3 (DSG3) and…”
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Randomized Phase II Trial of Gemcitabine Plus TH-302 Versus Gemcitabine in Patients With Advanced Pancreatic Cancer by Borad, Mitesh J, Reddy, Shantan G, Bahary, Nathan, Uronis, Hope E, Sigal, Darren, Cohn, Allen L, Schelman, William R, Stephenson, Jr, Joe, Chiorean, E Gabriela, Rosen, Peter J, Ulrich, Brian, Dragovich, Tomislav, Del Prete, Salvatore A, Rarick, Mark, Eng, Clarence, Kroll, Stew, Ryan, David P

“…TH-302 is an investigational hypoxia-activated prodrug that releases the DNA alkylator bromo-isophosphoramide mustard in hypoxic settings. This phase II study…”
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Palliative sedation: when the family and consulting service see no alternative by Del Fabbro, Egidio, Reddy, Shantan G, Walker, Paul, Bruera, Eduardo

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TH-302 plus gemcitabine (G+T) versus gemcitabine (G) in patients with previously untreated advanced pancreatic cancer (PAC) by Ryan, David P., Reddy, Shantan G., Bahary, Nathan, Uronis, Hope Elizabeth, Sigal, Darren, Cohn, Allen Lee, Schelman, William R., Stephenson, Joe, Eng, Clarence, Borad, Mitesh J.

“…Abstract only 325 Background: TH-302 is a hypoxia-targeted drug with a hypoxia-triggered 2-nitroimidazole component designed to release the DNA alkylator,…”
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