Search Results - "Reddy, Panga Jaipal"
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Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
Published in Science (American Association for the Advancement of Science) (02-02-2024)“…Increasing use of covalent and noncovalent inhibitors of Bruton's tyrosine kinase (BTK) has elucidated a series of acquired drug-resistant BTK mutations in…”
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2
Protein microarrays and novel detection platforms
Published in Expert review of proteomics (01-02-2011)“…The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for…”
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Proteomic Analysis of Plasmodium Merosomes: The Link between Liver and Blood Stages in Malaria
Published in Journal of proteome research (06-09-2019)“…The pre-erythrocytic liver stage of the malaria parasite, comprising sporozoites and the liver stages into which they develop, remains one of the least…”
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mRNA transcript distribution bias between Borrelia burgdorferi bacteria and their outer membrane vesicles
Published in FEMS microbiology letters (01-07-2018)“…Borrelia burgdorferi, a bacterium in the spirochete phylum, is the causative agent of Lyme disease. Borrelia burgdorferi has a linear chromosome with a number…”
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Identification of Highly Expressed Plasmodium Vivax Proteins from Clinical Isolates Using Proteomics
Published in Proteomics. Clinical applications (01-07-2018)“…Plasmodium vivax is the most geographically widespread species responsible for malaria in humans. Our study focused on identifying highly expressed parasite…”
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Recent Progress in Lyme Disease and Remaining Challenges
Published in Frontiers in medicine (18-08-2021)“…Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in the United States with an estimated 476,000 cases per year. While…”
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Global proteomic profiling identifies etoposide chemoresistance markers in non-small cell lung carcinoma
Published in Journal of proteomics (14-04-2016)“…Chemoresistance is one of the leading health concerns in cancer treatment. Understanding the mechanism of chemoresistance is the best way to improve the…”
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Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1
Published in PloS one (11-06-2018)“…Lyme disease is caused by spirochaetes of the Borrelia burgdorferi sensu lato genospecies. Complete genome assemblies are available for fewer than ten strains…”
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A comprehensive spectral assay library to quantify the Escherichia coli proteome by DIA/SWATH-MS
Published in Scientific data (12-11-2020)“…Data-Independent Acquisition (DIA) is a method to improve consistent identification and precise quantitation of peptides and proteins by mass spectrometry…”
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The PeptideAtlas of a widely cultivated fish Labeo rohita: A resource for the Aquaculture Community
Published in Scientific data (13-04-2022)“…Labeo rohita (Rohu) is one of the most important fish species produced in world aquaculture. Integrative omics research provides a strong platform to…”
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Quantitative mass spectrometry analysis reveals a panel of nine proteins as diagnostic markers for colon adenocarcinomas
Published in Oncotarget (02-03-2018)“…Adenocarcinomas are cancers originating from the gland forming cells of the colon and rectal lining, and are known to be the most common type of colorectal…”
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Comprehensive analysis of temporal alterations in cellular proteome of Bacillus subtilis under curcumin treatment
Published in PloS one (14-04-2015)“…Curcumin is a natural dietary compound with antimicrobial activity against various gram positive and negative bacteria. This study aims to investigate the…”
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Correction: Comprehensive Analysis of Temporal Alterations in Cellular Proteome of Bacillus subtilis under Curcumin Treatment
Published in PloS one (17-06-2015)“…[This corrects the article DOI: 10.1371/journal.pone.0120620.]…”
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14
Cancer Biomarker Detection by Surface Plasmon Resonance Biosensors
Published in Clinics in laboratory medicine (01-03-2012)Get full text
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The quest of the human proteome and the missing proteins: digging deeper
Published in Omics (Larchmont, N.Y.) (01-05-2015)“…Given the diverse range of transcriptional and post-transcriptional mechanisms of gene regulation, the estimates of the human proteome is likely subject to…”
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Label-free plasma proteomics for the identification of the putative biomarkers of oral squamous cell carcinoma
Published in Journal of proteomics (15-05-2022)“…Mass spectrometry-based label-free proteomics is becoming the analytical tool of interest to identify and quantitate the biomarkers for cancer. The oral…”
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17
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
Published in Journal of medicinal chemistry (22-02-2024)“…Bruton’s tyrosine kinase (BTK), a member of the TEC family of kinases, is an essential effector of B-cell receptor (BCR) signaling. Chronic activation of…”
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Organ-Based Proteome and Post-Translational Modification Profiling of a Widely Cultivated Tropical Water Fish, Labeo rohita
Published in Journal of proteome research (04-02-2022)“…Proteomics has enormous applications in human and animal research. However, proteomic studies in fisheries science are quite scanty particularly for…”
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Circulating Angiopoietin-like 8 protein (ANGPTL8/Betatrophin) in patients with polycystic ovary syndrome: a systematic review and multi effect size meta-analysis
Published in Gynecological endocrinology (04-03-2019)“…The association between circulating betatrophin levels and polycystic ovary syndrome (PCOS) is controversial and the studies in the literature are…”
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Circulatory metastin/kisspeptin-1 in polycystic ovary syndrome: a systematic review and meta-analysis with diagnostic test accuracy
Published in Reproductive biomedicine online (01-10-2019)“…A close association between Kisspeptin-1 (KISS-1) and reproductive physiology has been reported, but the results on circulatory KISS-1 are ambiguous in…”
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