Search Results - "Reddy, Maryada Venkata Rami"

Immune responses generated by intramuscular DNA immunization of Brugia malayi transglutaminase (BmTGA) in mice by Vanam, Uma, Prabhu, Prince R, Pandey, Vivek, Dakshinamurthy, Gajalakshmi, Reddy, Maryada Venkata Rami, Perumal, Kaliraj

“…An attempt was made to evaluate the immunoprophylactic efficacy of Brugia malayi transglutaminase (BmTGA) as a DNA vaccine, for human lymphatic filariasis…”
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The Larval Specific Lymphatic Filarial ALT-2: Induction of Protection Using Protein or DNA Vaccination by Ramachandran, Sabarinathan, Kumar, Mishra Pankaj, Rami, Reddy Maryada Venkata, Chinnaiah, Harinath Basker, Nutman, Thomas, Kaliraj, Perumal, McCarthy, James

“…Genes from the infective stage of lymphatic filarial parasites expressed at the time of host invasion have been identified as potential vaccine candidates. By…”
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Immunoprophylaxis of multi-antigen peptide (MAP) vaccine for human lymphatic filariasis by Immanuel, Christiana, Ramanathan, Aparnaa, Balasubramaniyan, Malathi, Khatri, Vishal Kishor, Amdare, Nitin Purushottam, Rao, Donthamsetty Nageswara, Reddy, Maryada Venkata Rami, Perumal, Kaliraj

“…Human lymphatic filariasis, the parasitic disease caused by the filarial nematodes Wuchereria bancrofti , Brugia malayi , and Brugia timori , is ranked as the…”
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Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis by Veerapathran, Anandharaman, Dakshinamoorthy, Gajalakshmi, Gnanasekar, Munirathinam, Reddy, Maryada Venkata Rami, Kalyanasundaram, Ramaswamy

“…Lymphatic filarial parasites survive within the lymphatic vessels for years despite the complex immune environment surrounding them. Parasites possibly…”
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Immunization with Wuchereria bancrofti Glutathione-S-transferase Elicits a Mixed Th1/Th2 Type of Protective Immune Response Against Filarial Infection in Mastomys by Andure, Dhananjay, Pote, Kiran, Khatri, Vishal, Amdare, Nitin, Padalkar, Ramchandra, Reddy, Maryada Venkata Rami

“…Lymphatic filariasis is a mosquito borne parasitic infection and can severely affect the normal working ability of an individual. Currently there is no vaccine…”
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Filarial Abundant Larval Transcript Protein ALT-2: An Immunomodulatory Therapeutic Agent for Type 1 Diabetes by Reddy, Sridhar M., Reddy, Pooja M., Amdare, Nitin, Khatri, Vishal, Tarnekar, Aaditya, Goswami, Kalyan, Reddy, Maryada Venkata Rami

“…Type 1 diabetes (T1D) that accounts for about 5–10 % of all diabetes cases results from the autoimmune destruction of the insulin-producing beta cells in the…”
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Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in experimental mice model by Paul, Rajkumar, Ilamaran, Meganathan, Khatri, Vishal, Amdare, Nitin, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Filariasis, a neglected tropical helminth disease needs vaccine besides mass drug administration for its successful eradication. An attempt was made to produce…”
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Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis by Madhumathi, Jayaprakasam, Prince, Prabhu Rajaiah, Anugraha, Gandhirajan, Kiran, Pote, Rao, Donthamsetty Nageswara, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Abstract Although multi-epitope vaccines have been evaluated for various diseases, they have not yet been investigated for lymphatic filariasis. Here, we…”
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The adjuvant-free immunoprotection of recombinant filarial protein Abundant Larval Transcript-2 (ALT-2) in Mastomys coucha and the immunoprophylactic importance of its putative signal sequence by Sharmila, Sam, Christiana, Immanuel, Kiran, Pote, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…[Display omitted] ► Brugia malayi ALT-2 produces 71% worm clearance in Mastomys coucha even without adjuvant. ► Adjuvant-free immunoprotection of ALT-2…”
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Evaluation of Immunoprophylactic Efficacy of Brugia malayi Transglutaminase (BmTGA) in Single and Multiple Antigen Vaccination with BmALT-2 and BmTPX for Human Lymphatic Filariasis by Vanam, Uma, Pandey, Vivek, Prabhu, Prince R, Dakshinamurthy, Gajalakshmi, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…An attempt was made to study the immunoprophylactic efficacy of recombinant Brugia malayi transglutaminase (BmTGA) as protein vaccine along with two other…”
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Comparison of immunogenicity, protective efficacy of single and cocktail DNA vaccine of Brugia malayi abundant larval transcript (ALT-2) and thioredoxin peroxidase (TPX) in mice by Anand, Setty Balakrishnan, Murugan, Vadivel, Prabhu, Prince Rajaiah, Anandharaman, Veerabhadran, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Although DNA vaccines have several advantages over conventional vaccines, antibody production and protection are often not adequate, particularly in single…”
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Brugia malayi: Comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model by Thirugnanam, Sivasakthivel, Pandiaraja, Pandurangan, Ramaswamy, Kalyanasundaram, Murugan, Vadivel, Gnanasekar, Munirathinam, Nandakumar, Krithika, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Immunization of jirds with Bm-alt-2 elicited partial protection against challenge infection with the filarial parasite Brugia malayi. In this study, we…”
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Vaccination with Setaria cervi 175 kDa collagenase induces high level of protection against Brugia malayi infection in jirds by Pokharel, Daya Ram, Rai, Reeta, Nandakumar Kodumudi, Krithika, Reddy, Maryada Venkata Rami, Rathaur, Sushma

“…A zinc containing metalloprotease, 175 kDa collagenase, purified from adult female Setaria cervi showed strong cross-reactivity with sera from putatively…”
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Targeting Folate Metabolism: A Promising Therapeutic Rationale against Brugia malayi Infection by Bhoj, Priyanka, Hande, Sneha, Wagh, Suraj, Sharma, Richa, Goswami, Kalyan, Jena, Lingaraj, Reddy, Maryada Venkata Rami

“…Lymphatic filariasis although not fatal, is a profoundly disabling disease, with an estimated level of 5.8 million disability adjusted life year. Besides being…”
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Analysis of Polymorphism of 18S rRNA Gene in Wuchereria bancrofti Microfilariae by Bhandari, Yashodhar, Dabir, Pankaj, Nandhakumar, Krithika, Dayananda, Kannayakanahalli Maheshwarappa, Shouche, Yogesh Shripad, Reddy, Maryada Venkata Rami

“…The polymorphism of the 18S rRNA gene in Wuchereria bancrofti microfilariae (mf) collected from three different zones in India was analyzed by polymerase chain…”
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Brugia malayi cystatin therapeutically ameliorates dextran sulfate sodium-induced colitis in mice by Khatri, Vishal, Amdare, Nitin, Tarnekar, Aaditya, Goswami, Kalyan, Reddy, Maryada Venkata Rami

“…Objective Helminth immunomodulation in the host has been shown to have therapeutic implications in inflammatory bowel diseases. In this study we aimed to…”
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Targeting folate metabolism for therapeutic option: A bioinformatics approach by Hande, Sneha, Goswami, Kalyan, Sharma, Richa, Bhoj, Priyanka, Jena, Lingaraj, Reddy, Maryada Venkata Rami

“…Lymphatic filariasis, commonly called elephantiasis, poses a burden of estimated level of 5.09 million disability adjusted life year. Limitations of its sole…”
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Brugia malayi abundant larval transcript 2 protein treatment attenuates experimentally-induced colitis in mice by Khatri, Vishal, Amdare, Nitin, Yadav, Ravi Shankar, Tarnekar, Aaditya, Goswami, Kalyan, Reddy, Maryada Venkata Rami

“…Helminths are known to modulate host's immunity by suppressing host protective pro-inflammatory responses. Such immunomodulatory effects have been…”
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Exploring apposite therapeutic target for apoptosis in filarial parasite: A plausible hypothesis by Hande, Sneha, Goswami, Kalyan, Jena, Lingaraj, Reddy, Maryada Venkata Rami

“…Abstract Human lymphatic filariasis is a parasitic disease with profound socioeconomic encumbrance owing to its associated disability, affecting predominantly…”
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Antifilarial actions of green tea extract and a synthetic heterocyclic thiazolidine derivative, Im8 compound in experimental mouse model by Hande, Sneha, Goswami, Kalyan, Togre, Namdev, Mandvikar, Amisha, Rami Reddy, Maryada Venkata

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