Search Results - "Reddy, Mali V"
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Chemistry and Biology of Diazonamide A: Second Total Synthesis and Biological Investigations
Published in Journal of the American Chemical Society (13-10-2004)“…As an especially unique target for chemical synthesis, diazonamide A has the potential to be constructed through a plethora of synthetic routes, each attended…”
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A Novel Regio- and Stereoselective Synthesis of Sulfamidates from 1,2-Diols Using Burgess and Related Reagents: A Facile Entry into β-Amino Alcohols
Published in Angewandte Chemie International Edition (01-03-2002)“…An increasingly targeted functional motif in organic synthesis is the ubiquitous chiral β‐amino alcohol. A novel two‐step approach for the regio‐ and…”
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Studies toward Diazonamide A: Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure
Published in Journal of the American Chemical Society (18-08-2004)“…In this article, we describe further studies toward the originally proposed structure of diazonamide A (1). After confronting a number of failures in…”
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Construction of the Complete Aromatic Core of Diazonamide A by a Novel Hetero Pinacol Macrocyclization Cascade Reaction
Published in Angewandte Chemie International Edition (17-12-2001)“…One of the most enticing natural products isolated in recent years and a serious challenge to synthetic chemists is represented by the potent anticancer agent…”
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Studies toward Diazonamide A: Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure [J. Am. Chem. Soc. 2004, 126, 10174−10182]
Published in Journal of the American Chemical Society (24-11-2004)Get full text
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Construction of the Complete Aromatic Core of Diazonamide A by a Novel Hetero Pinacol Macrocyclization Cascade Reaction We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), American Biosciences, a predoctoral fellowship from the National Science Foundation (S.A.S.), a postdoctoral fellowship from the Associa
Published in Angewandte Chemie International Edition (17-12-2001)Get full text
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Construction of the Complete Aromatic Core of Diazonamide A by a Novel Hetero Pinacol Macrocyclization Cascade Reaction
Published in Angewandte Chemie (17-12-2001)“…Das stark antitumorwirksame Diazonamid A 1 stellt einen der verlockendsten Naturstoffe dar, die in den letzten Jahren isoliert wurden, und ist eine große…”
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A Novel Regio- and Stereoselective Synthesis of Sulfamidates from 1,2-Diols Using Burgess and Related Reagents: A Facile Entry into β-Amino Alcohols We thank Professor K. Barry Sharpless for the gracious donation of several of the starting diol substrates. We also thank Drs. D. H. Huang, G. Suizdak, and R. Chadja for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology
Published in Angewandte Chemie International Edition (01-03-2002)Get full text
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A Novel Regio- and Stereoselective Synthesis of Sulfamidates from 1,2-Diols Using Burgess and Related Reagents: A Facile Entry into β-Amino Alcohols
Published in Angewandte Chemie (01-03-2002)“…Eine funktionelle Gruppe mit zunehmender Bedeutung in der organischen Synthese ist die häufig vorkommende β‐Aminoalkohol‐Einheit. Ein neuartiger zweistufiger…”
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