Search Results - "Reddy, Kondreddi Ravinder"
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Translation Inhibitor That Suppresses Dengue Virus In Vitro and In Vivo
Published in Antimicrobial Agents and Chemotherapy (01-09-2011)“…We describe a novel translation inhibitor that has anti-dengue virus (DENV) activity in vitro and in vivo. The inhibitor was identified through a…”
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Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides: A Promising Class of Antituberculosis Agents
Published in Journal of medicinal chemistry (14-11-2013)“…Indole-2-carboxamides have been identified as a promising class of antituberculosis agents from phenotypic screening against mycobacteria. One of the hits,…”
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adenosine nucleoside inhibitor of dengue virus
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-2009)“…Dengue virus (DENV), a mosquito-borne flavivirus, is a major public health threat. The virus poses risk to 2.5 billion people worldwide and causes 50 to 100…”
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Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents
Published in European journal of medicinal chemistry (01-12-2015)“…Pyridone 1 was identified from a high-throughput cell-based phenotypic screen against Mycobacterium tuberculosis (Mtb) including multi-drug resistant…”
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Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements
Published in Angewandte Chemie International Edition (01-01-2007)“…Pairing up: Oligodipeptide, oligodeoxydipeptide, or oligodipeptoid backbones tagged with the 2,4‐diaminotriazine nucleus pair strongly with complementary DNA…”
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Inhibition of Dengue Virus RNA Synthesis by an Adenosine Nucleoside
Published in Antimicrobial Agents and Chemotherapy (01-07-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides Tagged with 2,4-Disubstituted 5-Aminopyrimidines as Recognition Elements
Published in Angewandte Chemie International Edition (01-01-2007)“…Bit different: 2,4‐Dioxo‐ and 2,4‐diamino‐5‐aminopyrimidine nuclei attached to an oligodipeptide backbone display a disparity in their base‐pairing strength…”
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N-Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase
Published in Journal of medicinal chemistry (24-12-2009)“…A novel class of compounds containing N-sulfonylanthranilic acid was found to specifically inhibit dengue viral polymerase. The structural requirements for…”
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Direct inhibitors of InhA are active against Mycobacterium tuberculosis
Published in Science translational medicine (07-01-2015)“…New chemotherapeutic agents are urgently required to combat the global spread of multidrug-resistant tuberculosis (MDR-TB). The mycobacterial enoyl reductase…”
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Design and synthesis of trans-3-aminopyran-2-carboxylic acid (APyC) and α/β-peptides with 9/11-helix
Published in Organic & biomolecular chemistry (07-12-2011)“…A new β-amino acid, trans-3-aminopyran-2-carboxylic acid (APyC), was designed and synthesized from (R)-glyceraldehyde derivative and used in the synthesis of…”
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Cover Picture: Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements / Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides Tagged with 2,4-Disubstituted 5-Aminopyrimidines as Recognition Elements (Angew. Chem. Int. Ed. 14/2007)
Published in Angewandte Chemie International Edition (26-03-2007)“…2,4‐Dioxo‐ and 2,4‐diamino derivatives of the 5‐aminopyrimidine nucleus, which are attached to an oligodipeptide backbone, display inverse base‐pairing…”
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N Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerise
Published in Journal of medicinal chemistry (2009)Get full text
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Left‐Handed Helical Twists in “Mixed β‐Peptides” Derived From Alternating C‐Linked Carbo‐β 3 ‐Amino Acids and β‐hGly Units
Published in Angewandte Chemie International Edition (26-07-2004)Get full text
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Left-Handed Helical Twists in "Mixed β-Peptides" Derived From Alternating C-Linked Carbo-β3-Amino Acids and β-hGly Units
Published in Angewandte Chemie International Edition (26-07-2004)“…Ambidextrous peptides: Novel mixed β‐peptides were synthesized from alternating C‐linked carbo‐β3‐amino acid and β‐homoglycine residues. The peptides form…”
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Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides Tagged with 2,4-Disubstituted 5-Aminopyrimidines as Recognition Elements
Published in Angewandte Chemie (26-03-2007)“…Krass verschieden: 2,4‐Dioxo‐ und 2,4‐Diamino‐5‐aminopyrimidinkerne, die an Oligodipeptidgerüste gebunden sind, unterscheiden sich in ihrer Fähigkeit zur…”
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Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements
Published in Angewandte Chemie (26-03-2007)“…Paarbildung: Oligodipeptid‐, Oligodesoxydipeptid‐ oder Oligodipeptoidgerüste, die mit dem 2,4‐Diaminotriazinkern markiert wurden, bilden starke Paare mit…”
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Titelbild: Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements (Angew. Chem. 14/2007)
Published in Angewandte Chemie (26-03-2007)“…2,4‐Dioxo‐ und 2,4‐Diaminoderivate von 5‐Aminopyrimidin, die an ein Oligodipeptid‐Rückgrat gebunden sind, zeigen eine umgekehrte Reihenfolge der…”
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Left-Handed Helical Twists in "Mixed β-Peptides" Derived From Alternating C-Linked Carbo-β3-Amino Acids and β-hGly Units
Published in Angewandte Chemie (26-07-2004)“…Beidhändige Peptide: Die hier vorgestellten neuartigen gemischten β‐Peptide mit alternierend C‐verknüpften Carbo‐β3‐aminosäuren und β‐Homoglycin‐Resten bilden…”
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