Search Results - "Reddy, Heather L."

Primary hemostatic capacity of whole blood: a comprehensive analysis of pathogen reduction and refrigeration effects over time by Pidcoke, Heather F., McFaul, Steve J., Ramasubramanian, Anand K., Parida, Bijaya K., Mora, Alex G., Fedyk, Chriselda G., Valdez-Delgado, Krystal K., Montgomery, Robbie K., Reddoch, Kristin M., Rodriguez, Armando C., Aden, James K., Jones, John A., Bryant, Ron S., Scherer, Michael R., Reddy, Heather L., Goodrich, Raymond P., Cap, Andrew P.

“…Background Whole blood (WB) has been used in combat since World War I as it is readily available and replaces every element of shed blood. Component therapy…”
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Red Blood Cells Derived from Whole Blood Treated with Riboflavin and UV Light Maintain Adequate Cell Quality through 21 Days of Storage by Dimberg, Lina Y., Doane, Suzann K., Yonemura, Susan, Reddy, Heather L., Hovenga, Nick, Gosney, E. Jane, Tran, Melissa , Wilkinson, Shilo, Goodrich, Raymond P., Marschner, Susanne

“…Background: The Mirasol system for whole blood (WB) is a non-toxic, non-mutagenic pathogen reduction technology (PRT) that treats WB units with riboflavin…”
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Treatment of whole blood with riboflavin plus ultraviolet light, an alternative to gamma irradiation in the prevention of transfusion-associated graft-versus-host disease? by Fast, Loren D., Nevola, Martha, Tavares, Jennifer, Reddy, Heather L., Goodrich, Ray P., Marschner, Susanne

“…BACKGROUND: Exposure of blood products to gamma irradiation is currently the standard of care in the prevention of transfusion‐associated graft‐versus‐host…”
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Reduction of Leishmania donovani infectivity in whole blood using riboflavin and ultraviolet light by Tonnetti, Laura, Thorp, Aaron M., Reddy, Heather L., Keil, Shawn D., Doane, Suzann K., Goodrich, Raymond P., Leiby, David A.

“…Background Leishmaniasis is a vector‐borne disease caused by the protozoan parasite Leishmania sp. that is transmitted by sandflies. Travelers to endemic…”
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Design and development of a method for the reduction of infectious pathogen load and inactivation of white blood cells in whole blood products by Goodrich, Raymond P., Doane, Suzann, Reddy, Heather L.

“…The use of blood components has been a staple of transfusion medicine for several decades. Technologies for the processing and handling of blood, including…”
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Development of a riboflavin and ultraviolet light-based device to treat whole blood by Reddy, Heather L., Doane, Suzann K., Keil, Shawn D., Marschner, Susanne, Goodrich, Raymond P.

“…Background In the United States, blood components are commonly used for patients in need of massive transfusion after blood loss. In combat situations, when…”
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Toxicity Testing of a Novel Riboflavin-Based Technology for Pathogen Reduction and White Blood Cell Inactivation by Reddy, Heather L, Dayan, Anthony D, Cavagnaro, Joy, Gad, Shayne, Li, Junzhi, Goodrich, Raymond P

“…The Mirasol PRT System (Gambro BCT, Lakewood, CO) for platelets and plasma uses riboflavin and UV light to reduce pathogens and inactivate white blood cells in…”
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Fresh Whole Blood Use for Hemorrhagic Shock: Preserving Benefit While Avoiding Complications by Spinella, Philip C., Reddy, Heather L., Jaffe, Jennifer S., Cap, Andrew P., Goodrich, Raymond P.

“…Transfusion support of patients with hemorrhagic shock has changed over time with the development of storage and processing methods. Transfusion medicine…”
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Riboflavin and ultraviolet light reduce the infectivity of Babesia microti in whole blood by Tonnetti, Laura, Thorp, Aaron M., Reddy, Heather L., Keil, Shawn D., Goodrich, Raymond P., Leiby, David A.

“…BACKGROUND: Babesia microti is the parasite most frequently transmitted by blood transfusion in the United States. Previous work demonstrated the efficacy of…”
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Evaluation of the Mirasol platelet reduction technology system against Babesia microti in apheresis platelets and plasma by Tonnetti, Laura, Proctor, Melanie C., Reddy, Heather L, Goodrich, Raymond P., Leiby, David A.

“…BACKGROUND: Babesia microti is an intraerythrocytic parasite, transmitted naturally to humans by infected ixodid ticks, that causes babesiosis. In recent…”
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Inactivation of Plasmodium spp. in plasma and platelet concentrates using riboflavin and ultraviolet light by Keil, Shawn D., Kiser, Patti, Sullivan, James J., Kong, Amy S., Reddy, Heather L., Avery, Anne, Goodrich, Raymond P.

“…Background Photochemical treatment of blood products could help prevent transfusion‐transmitted malaria and reduce the need for donor deferrals. In this study…”
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Evaluating pathogen reduction of Trypanosoma cruzi with riboflavin and ultraviolet light for whole blood by Tonnetti, Laura, Thorp, Aaron M., Reddy, Heather L., Keil, Shawn D., Goodrich, Raymond P., Leiby, David A.

“…BACKGROUND: Trypanosoma cruzi, the protozoan parasitic agent of Chagas disease, can be transmitted by blood transfusion. In 2007, most US blood banks started…”
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In vivo viability of stored red blood cells derived from riboflavin plus ultraviolet light-treated whole blood by Cancelas, Jose A., Rugg, Neeta, Fletcher, Dana, Pratt, P. Gayle, Worsham, D. Nicole, Dunn, Susan K., Marschner, Susanne, Reddy, Heather L., Goodrich, Raymond P.

“…BACKGROUND: A novel system using ultraviolet (UV) light and riboflavin (Mirasol System, CaridianBCT Biotechnologies) to fragment nucleic acids has been…”
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Evaluation of potential immune response and in vivo survival of riboflavin-ultraviolet light-treated red blood cells in baboons by Goodrich, Raymond P., Murthy, Krishna K., Doane, Suzann K., Fitzpatrick, Christy N., Morrow, La Shayla, Arndt, Patricia A., Reddy, Heather L., Buytaert-Hoefen, Kimberley A., Garratty, George

“…BACKGROUND: Pathogen reduction methods have the potential to modify blood components, resulting in immunologic reactions or compromised blood components. This…”
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Reduction of L eishmania donovani infectivity in whole blood using riboflavin and ultraviolet light by Tonnetti, Laura, Thorp, Aaron M., Reddy, Heather L., Keil, Shawn D., Doane, Suzann K., Goodrich, Raymond P., Leiby, David A.

“…Background Leishmaniasis is a vector‐borne disease caused by the protozoan parasite L eishmania sp. that is transmitted by sandflies. Travelers to endemic…”
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Inactivation of P lasmodium spp. in plasma and platelet concentrates using riboflavin and ultraviolet light by Keil, Shawn D., Kiser, Patti, Sullivan, James J., Kong, Amy S., Reddy, Heather L., Avery, Anne, Goodrich, Raymond P.

“…Background Photochemical treatment of blood products could help prevent transfusion‐transmitted malaria and reduce the need for donor deferrals. In this study…”
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Pathogen Reduction Treatment of Whole Blood Inhibits Clot Lysis and Thrombin Generation Is Preserved to 14 Days by Storage At 4°C by Mora, Alejandra G, Pidcoke, Heather F, Valdez-Delgado, Krystal K, Fedyk, Chriselda G, Reddy, Heather L, Goodrich, Raymond, Cap, Andrew P

“…Abstract 2272 Fresh whole blood (WB) collected from a “walking blood bank” is used by the U.S. military to supplement component therapy when blood component…”
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Evaluation of potential immune response and in vivo survival of riboflavin-ultraviolet lightatreated red blood cells in baboons by Goodrich, Raymond P, Murthy, Krishna K, Doane, Suzann K, Fitzpatrick, Christy N, Morrow, La Shayla, Arndt, Patricia A, Reddy, Heather L, Buytaert-Hoefen, Kimberley A, Garratty, George

“…BACKGROUND: Pathogen reduction methods have the potential to modify blood components, resulting in immunologic reactions or compromised blood components. This…”
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Evaluation of the Mirasol pathogen [corrected] reduction technology system against Babesia microti in apheresis platelets and plasma by Tonnetti, Laura, Proctor, Melanie C, Reddy, Heather L, Goodrich, Raymond P, Leiby, David A

“…Babesia microti is an intraerythrocytic parasite, transmitted naturally to humans by infected ixodid ticks, that causes babesiosis. In recent years, B. microti…”
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Analysis of biodegradation and bacterial transport: Comparison of models with kinetic and equilibrium bacterial adsorption by Reddy, Heather L., Ford, Roseanne M.

“…An advection/dispersion/sorption model incorporating Monod kinetics (modified to describe bacterial growth near threshold concentrations of the contaminant)…”
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