Search Results - "Reddy, Haritha"

Ethosuximide is an allosteric blocker of girk channels with Gβγ and is subunit dependent by Shalomov, Boris, Combista, J. Carlo, Reddy, Haritha P., Dabbah, Shoham, Yakubovich, Daniel, Dascal, Nathan

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Immune Checkpoint Inhibitor-Associated Colits and Hepatitis by Reddy, Haritha G, Schneider, Bryan J, Tai, Andrew W

“…Immune checkpoint inhibitors (ICPIs) are monoclonal antibodies that target downregulators of the anti-cancer immune response: cytotoxic T-lymphocyte antigen-4,…”
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Cyclin-dependent kinase inhibitors for the treatment of lung cancer by Qin, Angel, Reddy, Haritha G, Weinberg, Frank D, Kalemkerian, Gregory P

“…Cyclin-dependent kinases (CDKs) are critical regulators of cell cycle progression in both normal and malignant cells, functioning through complex molecular…”
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A selectivity filter mutation provides insights into gating regulation of a K+ channel by Friesacher, Theres, Reddy, Haritha P., Bernsteiner, Harald, Combista, J. Carlo, Shalomov, Boris, Bera, Amal K., Plessl, Eva-Maria, Dascal, Nathan, Stary-Weinzinger, Anna

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Analyzing “Failure to Rescue”: Is This an Opportunity for Outcome Improvement in Cardiac Surgery? by Reddy, Haritha G., BA, Shih, Terry, MD, Englesbe, Michael J., MD, Shannon, Francis L., MD, Theurer, Patricia F., BSN, Herbert, Morley A., PhD, Paone, Gaetano, MD, MHSA, Bell, Gail F., MSN, Prager, Richard L., MD

“…Background In the setting of a statewide quality collaborative approach to the review of cardiac surgical mortalities in intensive care units (ICUs),…”
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A revised mechanism of action of hyperaldosteronism‐linked mutations in cytosolic domains of GIRK4 (KCNJ5) by Shalomov, Boris, Handklo‐Jamal, Reem, Reddy, Haritha P., Theodor, Neta, Bera, Amal K., Dascal, Nathan

“…G protein‐gated, inwardly rectifying potassium channels (GIRK) mediate inhibitory transmission in brain and heart, and are present in the adrenal cortex. GIRK4…”
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Emerging drugs for small cell lung cancer: a focused review on immune checkpoint inhibitors by Reddy, Haritha G, Qin, Angel, Kalemkerian, Gregory P

“…Small cell lung cancer (SCLC) is an aggressive malignancy that accounts for 15% of all lung cancers. It is characterized by initial responsiveness to therapy…”
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Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor by Colombo, Sophie, Reddy, Haritha P, Petri, Sabrina, Williams, Damian J, Shalomov, Boris, Dhindsa, Ryan S, Gelfman, Sahar, Krizay, Daniel, Bera, Amal K, Yang, Mu, Peng, Yueqing, Makinson, Christopher D, Boland, Michael J, Frankel, Wayne N, Goldstein, David B, Dascal, Nathan

“…mutations in , encoding the G subunit of G proteins, cause a neurodevelopmental disorder with global developmental delay and epilepsy, encephalopathy. Here, we…”
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Real-world comparison of immune checkpoint inhibitors in non-small cell lung cancer following platinum-based chemotherapy by Weis, Taylor M, Hough, Shannon, Reddy, Haritha G, Daignault-Newton, Stephanie, Kalemkerian, Gregory P

“…Purpose Immunotherapy is a relatively new treatment modality for advanced non-small cell lung cancer following platinum-based chemotherapy. Nivolumab,…”
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Cyclin-dependent kinase 4 expression is essential for neu-induced breast tumorigenesis by Reddy, Haritha K D L, Mettus, Richard V, Rane, Sushil G, Graña, Xavier, Litvin, Judith, Reddy, E Premkumar

“…Previous work has shown that cyclin D1 expression is required for neu- and ras-induced, but not wnt- or c-myc-induced, breast tumorigenesis in mice. Although…”
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A Case Report of Whitmore's Disease: A True Masquerader by Patil, Chandrashekar, Mangalagiri, Nikhitha, Ajmera, Prakash, Kumar Ks, Prashanth, Reddy, Haritha

“…Melioidosis is an uncommon bacterial infection that is endemic to countries like Southeast Asia and Northern Australia but less common in temperate zones than…”
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Utilization of extracorporeal life support for diffuse alveolar damage and diffuse alveolar hemorrhage: A systematic review by Reddy, Haritha G., Maynes, Elizabeth J., Saxena, Abhiraj, Austin, Melissa A., O’Malley, Thomas J., Gadda, Marc N., Al‐Rawas, Nawar N., Baram, Michael, Awsare, Bharat K., Massey, H. Todd, Tchantchaleishvili, Vakhtang

“…Modern extracorporeal life‐support (ECLS) technology has been successfully utilized to treat patients with diffuse alveolar damage (DAD) and diffuse alveolar…”
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CFD simulation of the heat transfer using nanofluids in microchannel with dimple and protrusion by Madhava Reddy, Haritha, Venu Vinod, Ananthula

“…In this study, the heat transfer characteristics of CuO-H 2 O nanofluid flowing through a microchannel having dimples/protrusions were investigated. The effect…”
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GIRK-SPECIFIC DRUGS RESCUE ALTERED CHANNEL ACTIVITY IN GNB1 ENCEPHALOPATHY by Reddy, Haritha, Yakubovitch, Daniel, Raifman, Tal, Pederson, Maria, Shalomov, Boris, Javitch, Jonathan, Bera, Amal, Dascal, Nathan

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The Neuropeptide Orexin-A Inhibits the GABAA Receptor by PKC and Ca2+/CaMKII-Dependent Phosphorylation of Its β1 Subunit by Sachidanandan, Divya, Reddy, Haritha P., Mani, Anitha, Hyde, Geoffrey J., Bera, Amal Kanti

“…Orexin-A and orexin-B (Ox-A, Ox-B) are neuropeptides produced by a small number of neurons that originate in the hypothalamus and project widely in the brain…”
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Heparin-induced thrombocytopenia during extracorporeal life support: incidence, management and outcomes by Choi, Jae Hwan, Luc, Jessica G. Y., Weber, Matthew P., Reddy, Haritha G., Maynes, Elizabeth J., Deb, Avijit K., Samuels, Louis E., Morris, Rohinton J., Massey, H. Todd, Loforte, Antonio, Tchantchaleishvili, Vakhtang

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A selectivity filter mutation provides insights into gating regulation of a K+ channel by Friesacher, Theres, Reddy, Haritha P., Bernsteiner, Harald, Carlo Combista, J., Shalomov, Boris, Bera, Amal K., Zangerl-Plessl, Eva-Maria, Dascal, Nathan, Stary-Weinzinger, Anna

“…G-protein coupled inwardly rectifying potassium (GIRK) channels are key players in inhibitory neurotransmission in heart and brain. We conducted molecular…”
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Driving digital transformation of comprehensive primary health services at scale in India: an enterprise architecture framework by Nadhamuni, Sunita, John, Oommen, Kulkarni, Mallari, Nanda, Eshan, Venkatraman, Sethuraman, Varma, Devesh, Balsari, Satchit, Gudi, Nachiket, Samantaray, Shantidev, Reddy, Haritha, Sheel, Vikas

“…In its commitment towards Sustainable Development Goals, India envisages comprehensive primary health services as a key pillar in achieving universal health…”
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Concomitant vs staged orthotopic liver transplant after cardiac surgical procedures by Reddy, Haritha G, Choi, Jae Hwan, Maynes, Elizabeth J, Carlson, Laura A, Gordon, Jonathan S, Horan, Dylan P, Khan, Jafir, Weber, Matthew P, Bodzin, Adam S, Morris, Rohinton J, Massey, Howard T, Tchantchaleishvili, Vakhtang

“…ABSTRACTBackgroundIn patients who require orthotopic liver transplant (OLT), cardiac surgery may be needed to optimize preoperative cardiac status for OLT. The…”
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Correction: Immune Checkpoint Inhibitor-Associated Colitis and Hepatitis by Reddy, Haritha G, Schneider, Bryan J, Tai, Andrew W

“…The original version of this Article contained an error in the spelling of colitis in the article title. It was incorrectly spelt as "colits". This has now…”
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