Search Results - "Reddy, Ghanta Mahesh"

Synthesis and characterization of critical process related impurities of an asthma drug – Zafirlukast by Goverdhan, Gilla, Raghupathi Reddy, Anumula, Himabindu, Vurimidi, Mahesh Reddy, Ghanta

“…Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the treatment of pulmonary disorders such as asthma. During the process development of…”
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Identification, characterization and synthesis of impurities of zafirlukast by Goverdhan, Gilla, Reddy, Anumula Raghupathi, Srinivas, Kurella, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

“…Zafirlukast is a drug in the treatment of pulmonary disorders such as asthma. During the process development of zafirlukast, five unknown impurities were…”
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An Improved Process for the Production of Rabeprazole Sodium Substantially Free from the Impurities by Ramchandra Reddy, Pingili, Himabindu, Vurimidi, Jaydeepkumar, Lilakar, Madhusudhan Reddy, Ganta, Vijaya Kumar, Jonnalagadda, Mahesh Reddy, Ghanta

“…The present work details the journey towards development of a simple and cost-viable process for large-scale synthesis of rabeprazole sodium substantially free…”
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An expedient and new synthesis of pyrrolo[1,2-b]pyridazine derivatives by Sagyam, Rajeshwar Reddy, Buchikonda, Ravinder, Pitta, Jaya Prakash, Vurimidi, Himabindu, Padi, Pratap Reddy, Ghanta, Mahesh Reddy

“…The reaction of 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-pentanoic acid phenylamide with tertiary butyl carbazate and subsequent condensation…”
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Novel Carbon-Carbon Bond Formation between N-Methyl-3-phenyl-3-hydroxypropylamine and Cresols Catalyzed by p-Toluenesulphonic Acid by Gopalakrishnan, M., Sureshkumar, P., Kanagarajan, V., Thanusu, J., Govindan, Shanmugam, Reddy Ghanta, Mahesh

“…The p-toluenesulphonic acid-catalyzed reaction between appropriate cresols and N-methyl-3-phenyl-3-hydroxypropylamine in refluxing toluene resulted in the…”
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Improved Synthesis of Irbesartan, an Antihypertensive Active Pharmaceutical Ingredient by Satyanarayana, Bollikonda, Sumalatha, Yasareni, Venkatraman, Sundram, Mahesh Reddy, Ghanta, Pratap Reddy, Padi

“…An improved synthesis of the antihypertensive drug irbesartan, based on the Suzuki reaction, has been described…”
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Isolation, Synthesis and Characterization of Rosiglitazone Maleate Impurities by Singamsetty Radha Krishna, Mandava Venkata Naga Brahmeshwar Rao, Tirmalaraju Satyanaryana Raju, Vurimidi Himabindu, Ghanta Mahesh Reddy

“…Three unknown impurities in rosiglitazone maleate 1 bulk drug at level below 0.1% (ranging from 0.05 to 0.1%) were detected by simple reverse phase high…”
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Concise and Alternative Synthesis of Zafirlukast, an Anti-Asthma Drug by Goverdhan, Gilla, Reddy, Anumula Raghupathi, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

“…Concise and alternative synthesis of zafirlukast (1) is described. The synthesis features fewer steps, convergent synthesis, and novel intermediates…”
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A Scaleable Synthesis of Dutasteride: A Selective 5α-Reductase Inhibitor by Satyanarayana, Komati, Srinivas, Katkam, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

“…An improved and scaleable process for Dutasteride (1), a synthetic 4-azasteroid derivative essentially used for the treatment of prostate diseases, is…”
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Synthesis and pharmacological evaluation of 5-[2′-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine derivatives as platelet aggregation inhibitors by Challa, Nageswar Rao, Mamidisetty, Balaji, Ghanta, Mahesh Reddy, Padi, Pratap Reddy

“…One pot synthesis and characterization of new 5-[2′-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5,6,7-tetrahydro-thieno[3,2-c]pyridines (3a–k) using amides…”
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An Improved and Scalable Process for Zafirlukast: An Asthma Drug by Goverdhan, Gilla, Reddy, Anumula Raghupathi, Sampath, Aalla, Srinivas, Kurella, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

“…An improved and scalable process for the large-scale production of zafirlukast (Accolate), an important drug for asthma, is discussed along with impurity and…”
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Synthesis and Spectral Characterization of Related Substances of Vardenafil, an Erectile Dysfunction Drug by Reddy, Vajrala Venkata, Naga Brahmeswara Rao, Mandava Venkata, Reddy, Ghanta Mahesh, Mukkanti, Khagga, Reddy, Ganta Madhusudhan

“…Vardenafil hydrochloride trihydrate (Levitra) is used to treat erectile dysfunction (ED) and is an inhibitor of phosphodiesterase type 5 (PDE-5) enzyme. It…”
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Synthesis and Characterization of Some New Benzimidazole Derivatives by Reddy, Pingili Ramchandra, Reddy, Ganta Madhusudan, Reddy, Ghanta Mahesh, Himabindu, Vurimidi

“…Synthesis of nine new benzimidazole derivatives was reported. The products were identified by 1 H NMR, mass spectroscopy, and infrared spectroscopy…”
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An Improved Synthesis of Memantine Hydrochloride:  Anti-Alzheimer's Drug by Reddy, Jambula Mukunda, Prasad, Ganji, Raju, Veeramalla, Ravikumar, Mylavarapu, Himabindu, Vurumidi, Reddy, Ghanta Mahesh

“…An economical new process route has been developed for the large-scale synthesis of memantine hydrochloride (1) an anti-Alzheimer's drug. The procedure…”
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Unexpected Synthesis of Highly Substituted Indole Derivatives by Sagyam, Rajeshwar Reddy, Vurimidi, Himabindu, Padi, Pratap Reddy, Srinivas, Katkam, Ghanta, Mahesh Reddy

“…An unexpected synthesis of highly substituted indole derivatives was provided by treating 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-pentanoic…”
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Improved One-Pot Synthesis of Telmisartan by Rao, Challa Nageswar, Naresh, Tondepu, Satyanarayana, Komati, Reddy, Bojja Ramachandra, Reddy, Ghanta Mahesh

“…Cost-effective and improved one-pot synthesis for telmisartan (1) is described that minimizes the reaction time and gives high-purity material…”
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Alternative Total Synthesis of (−)-Galanthamine Hydrobromide by Reddy, Jambula Mukunda, Kumar, Kotagiri Vijay, Raju, Veeramalla, Bhaskar, Bolguddu Vijay, Himabindu, Vurumidi, Bhattacharya, Apurba, Sundaram, Venkatram, Banerjee, Rahul, Reddy, Ghanta Mahesh, Bandichhor, Rakeshwar

“…An alternative total synthesis of (−)-galanthamine (1) hydrobromide, employing ecofriendly amidation, oxidative coupling, and classical resolution strategies…”
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An efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives by Sagyam, Rajeshwar Reddy, Padi, Pratap Reddy, Ghanta, Mahesh Reddy, Vurimidi, Himabindu

“…An efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives is reported…”
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New Synthesis of Simvastatin by Singamsetty, Radha Krishna, Vujjini, Satish Kumar, Manne, Nagaraju, Venkata Naga, Brahmeshwara Rao Mandava, Himabindu, Vurimidi, Battacharya, Apurba, Ghanta, Mahesh Reddy, Bandichhor, Rakeshwar

“…A noninfringing synthesis of simvastatin 1, starting from lovastatin 2, is presented. This synthesis features the protection of the free hydroxyl group of the…”
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Impurity profile study of dutasteride by Satyanarayana, K, Srinivas, K, Himabindu, V, Mahesh Reddy, G

“…During the process development of dutasteride in the laboratory analysis showed some impurity peaks in HPLC ranging from 0.05 to 0.1%. The same samples were…”
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