Search Results - "Reddy, Charu"

Behavioral origin of sound-evoked activity in mouse visual cortex by Bimbard, Célian, Sit, Timothy P. H., Lebedeva, Anna, Reddy, Charu B., Harris, Kenneth D., Carandini, Matteo

“…Sensory cortices can be affected by stimuli of multiple modalities and are thus increasingly thought to be multisensory. For instance, primary visual cortex…”
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High-Yield Methods for Accurate Two-Alternative Visual Psychophysics in Head-Fixed Mice by Burgess, Christopher P., Lak, Armin, Steinmetz, Nicholas A., Zatka-Haas, Peter, Bai Reddy, Charu, Jacobs, Elina A.K., Linden, Jennifer F., Paton, Joseph J., Ranson, Adam, Schröder, Sylvia, Soares, Sofia, Wells, Miles J., Wool, Lauren E., Harris, Kenneth D., Carandini, Matteo

“…Research in neuroscience increasingly relies on the mouse, a mammalian species that affords unparalleled genetic tractability and brain atlases. Here, we…”
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Spontaneous behaviors drive multidimensional, brainwide activity by Stringer, Carsen, Pachitariu, Marius, Steinmetz, Nicholas, Reddy, Charu Bai, Carandini, Matteo, Harris, Kenneth D

“…Neuronal populations in sensory cortex produce variable responses to sensory stimuli and exhibit intricate spontaneous activity even without external sensory…”
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Dopaminergic and Prefrontal Basis of Learning from Sensory Confidence and Reward Value by Lak, Armin, Okun, Michael, Moss, Morgane M., Gurnani, Harsha, Farrell, Karolina, Wells, Miles J., Reddy, Charu Bai, Kepecs, Adam, Harris, Kenneth D., Carandini, Matteo

“…Deciding between stimuli requires combining their learned value with one’s sensory confidence. We trained mice in a visual task that probes this combination…”
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Spatial modulation of visual responses arises in cortex with active navigation by Diamanti, E Mika, Reddy, Charu Bai, Schröder, Sylvia, Muzzu, Tomaso, Harris, Kenneth D, Saleem, Aman B, Carandini, Matteo

“…During navigation, the visual responses of neurons in mouse primary visual cortex (V1) are modulated by the animal's spatial position. Here we show that this…”
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Neutrophil Influx and Chemokine Production during the Early Phases of the Antitumor Response to the Vascular Disrupting Agent DMXAA (ASA404) by Wang, Liang-Chuan S., Thomsen, Lotte, Sutherland, Rachel, Reddy, Charu B., Tijono, Sofian M., Chen, Chun-Jen J., Angel, Catherine E., Dunbar, P. Rod, Ching, Lai-Ming

“…5,6-Dimethylxanthenone-4-acetic acid (DMXAA) acts through tumor vascular disruption and cytokine production and is the first of its class to enter phase 3…”
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Induction of tumour necrosis factor and interferon-γ in cultured murine splenocytes by the antivascular agent DMXAA and its metabolites by Wang, Liang-Chuan S., Reddy, Charu B., Baguley, Bruce C., Kestell, Philip, Sutherland, Rachel, Ching, Lai-Ming

“…The induction of haemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in transplantable murine tumours depends on the in situ synthesis of…”
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Neural correlates of blood flow measured by ultrasound by Nunez-Elizalde, Anwar O., Krumin, Michael, Reddy, Charu Bai, Montaldo, Gabriel, Urban, Alan, Harris, Kenneth D., Carandini, Matteo

“…Functional ultrasound imaging (fUSI) is an appealing method for measuring blood flow and thus infer brain activity, but it relies on the physiology of…”
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A transcriptomic axis predicts state modulation of cortical interneurons by Bugeon, Stéphane, Duffield, Joshua, Dipoppa, Mario, Ritoux, Anne, Prankerd, Isabelle, Nicoloutsopoulos, Dimitris, Orme, David, Shinn, Maxwell, Peng, Han, Forrest, Hamish, Viduolyte, Aiste, Reddy, Charu Bai, Isogai, Yoh, Carandini, Matteo, Harris, Kenneth D.

“…Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine molecular subtypes 1 – 6 , but it is not known whether these…”
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Spontaneous Behaviors Drive Multidimensional, Brain-wide Activity by Stringer, Carsen, Pachitariu, Marius, Steinmetz, Nicholas, Reddy, Charu Bai, Carandini, Matteo, Harris, Kenneth D.

“…Neuronal populations in sensory cortex produce variable responses to sensory stimuli, and exhibit intricate spontaneous activity even without external sensory…”
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Publisher Correction: A transcriptomic axis predicts state modulation of cortical interneurons by Bugeon, Stéphane, Duffield, Joshua, Dipoppa, Mario, Ritoux, Anne, Prankerd, Isabelle, Nicoloutsopoulos, Dimitris, Orme, David, Shinn, Maxwell, Peng, Han, Forrest, Hamish, Viduolyte, Aiste, Reddy, Charu Bai, Isogai, Yoh, Carandini, Matteo, Harris, Kenneth D.

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modeling of GM1 gangliosidosis using iPSC-derived cellular and organoid CNS models by Schmitt, Christopher E., Lee, Grace S., Onguka, Ouma, Wong, Victoria, Del Greco, Elizabeth, Sedighi, Faezeh, Reddy, Charu, Santosh, Swetha, Akinkugbe, Oluwayomi, Artz, Jacob, Kruse, Nikki, Chng, Chinping, Hallows, William C., Chen, Joseph C., Akeefe, Hassibullah, Silverman, Adam P., Huisman, Gjalt

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In vitro modeling of GM1 gangliosidosis using iPSC-derived cellular and organoid CNS models by Schmitt, Christopher E., Lee, Grace S., Onguka, Ouma, Wong, Victoria, Del Greco, Elizabeth, Sedighi, Faezeh, Reddy, Charu, Santosh, Swetha, Akinkugbe, Oluwayomi, Artz, Jacob, Kruse, Nikki, Chng, Chinping, Hallows, William C., Chen, Joseph C., Akeefe, Hassibullah, Silverman, Adam P., Huisman, Gjalt

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An engineered β-galactosidase with improved stability and cross-correction for the potential treatment of GM1 Gangliosidosis via AAV gene therapy by Reddy, Charu, Onguka, Ouma, Artz, Jacob, Schmitt, Christopher, Grossman, Adam, Santosh, Swetha, Akinkugbe, Oluwayomi, Wong, Victoria, Gebretsadik, Kahsay, Sedighi, Faezeh, Tang, Jinyan, Del Greco, Elizabeth, Lee, Grace S., Kruse, Nikki, Chng, Chinping, Duan, Da, Hallows, William C., Chen, Joseph C., Akeefe, Hassibullah, Silverman, Adam P., Huisman, Gjalt

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Engineering α-glucosidase to improve protein stability and cellular uptake for the potential treatment of Pompe disease by Botham, Rachel C., Hallows, William C., Reddy, Charu, Dellas, Nikki, Homan, David, Lao, Jessica, Zhu, Cynthia, Chng, Chinping, Sero, Antoinette, Miller, Matt, Choi, Su Jin, Sun, Baodong, McCluskie, Kerryn, Huisman, Gjalt, Silverman, Adam P.

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Synthesis and Biological Activity of Azido Analogues of 5,6-Dimethylxanthenone-4-acetic Acid for Use in Photoaffinity Labeling by Palmer, Brian D, Henare, Kimiora, Woon, See-Tarn, Sutherland, Rachel, Reddy, Charu, Wang, Liang-Chuan S, Kieda, Claudine, Ching, Lai-Ming

“…5,6-Dimethylxanthenone-4-acetic acid (1) is scheduled for phase III clinical trials as a vascular disrupting agent. However, its biochemical receptor(s) have…”
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Neutrophil Influx and Chemokine Production during the Early Phases of the Antitumor Response to the Vascular Disrupting Agent DMXAA (ASA404)1 by Wang, Liang-Chuan S, Thomsen, Lotte, Sutherland, Rachel, Reddy, Charu B, Tijono, Sofian M, Chen, Chun-Jen J, Angel, Catherine E, Dunbar, P Rod, Ching, Lai-Ming

“…5,6-Dimethylxanthenone-4-acetic acid (DMXAA) acts through tumor vascular disruption and cytokine production and is the first of its class to enter phase 3…”
Get full text

Synthesis and Biological Activity of Azido Analogues of 5,6-Dimethylxanthenone-4-acetic Acid for Use in Photoaffinity Labeling by Palmer, Brian D., Henare, Kimiora, Woon, See-Tarn, Sutherland, Rachel, Reddy, Charu, Wang, Liang-Chuan S., Kieda, Claudine, Ching, Lai-Ming

“…5,6-Dimethylxanthenone-4-acetic acid (1) is scheduled for phase III clinical trials as a vascular disrupting agent. However, its biochemical receptor(s) have…”
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A comparison of the ability of DMXAA and xanthenone analogues to activate NF-kappaB in murine and human cell lines by Woon, See-Tarn, Reddy, Charu B, Drummond, Catherine J, Schooltink, Mary Ann, Baguley, Bruce C, Kieda, Claudine, Ching, Lai-Ming

“…DMXAA (5,6-dimethylxanthenone-4-acetic acid), the most potent of a series of xanthenone (XAA) analogues developed in this laboratory, is currently undergoing…”
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