Search Results - "Reddington, Madonna"

The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granule-specific and dependent on genetic background by Novak, Edward K., Gautam, Rashi, Reddington, Madonna, Collinson, Lucy M., Copeland, Neal G., Jenkins, Nancy A., McGarry, Michael P., Swank, Richard T.

“…The ashen (ash) mouse, a model for Hermansky-Pudlak syndrome (HPS) and for a subset of patients with Griscelli syndrome, presents with hypopigmentation,…”
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Cocoa: a new mouse model for platelet storage pool deficiency by Novak, E K, Sweet, H O, Prochazka, M, Parentis, M, Soble, R, Reddington, M, Cairo, A, Swank, R T

“…We describe genetic, haematological and biochemical properties of a new mouse pigment mutant, cocoa (coa). Cocoa is a recessive mutation located on the…”
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Using Actors as Simulated Patients for Interprofessional Education by Panzarella, Karen, Rivers, Lynn, Bright, Beth, Whelan, Megan, Butterfoss, Kirsten, Russ, Linda, Case, Andrew, Brian, Stephanie, Ferro, Heather, DeMarco, Lisa, Dunford, Denise, Schmitz, Kendra, Kittleson, Helena, Kennedy, Mary, Brzykcy, Donna, Pownall, Lynn, Reddington, Madonna

“…Interprofessional education (IPE) in health profession training is recognized as a key to improving patient care in practice settings. Though recognized as…”
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A New Gene Which Regulates Platelet Dense Granules by Gautam, Rashi, Rusiniak, Michael E., Chintala, Sreenivasulu, Tan, Jian, Li, Wei, Novak, Edward K., Reddington, Madonna, Swank, Richard T., McGarry, Michael P.

“…Hermansky-Pudlak Syndrome (HPS) is a genetically heterogeneous disease characterized by defects in trafficking of intracellular vesicles to lysosome-related…”
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Sandy: a new mouse model for platelet storage pool deficiency by Swank, R T, Sweet, H O, Davisson, M T, Reddington, M, Novak, E K

“…Sandy (sdy) is a mouse mutant with diluted pigmentation which recently arose in the DBA/2J strain. Genetic tests indicate it is caused by an autosomal…”
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Inherited thrombocytopenia caused by reduced platelet production in mice with the gunmetal pigment gene mutation by NOVAK, E. K, REDDINGTON, M, ZHEN, L, STENBERG, P. E, JACKSON, C. W, MCGARRY, M P, SWANK, R. T

“…Hereditary macrothrombocytopenia and prolonged bleeding times are associated with the recessive mouse pigment dilution gene gunmetal (gm). Other platelet…”
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von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene [published erratum appears in Blood 1995 Sep 15;86(6):2461] by Nichols, WC, Cooney, KA, Mohlke, KL, Ballew, JD, Yang, A, Bruck, ME, Reddington, M, Novak, EK, Swank, RT, Ginsburg, D

“…An animal model for human type I von Willebrand disease (vWD) has been previously described in the inbred mouse strain RIIIS/J. Murine vWD is characterized by…”
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Inherited Abnormalities in Platelet Organelles and Platelet Formation and Associated Altered Expression of Low Molecular Weight Guanosine Triphosphate-Binding Proteins in the Mouse Pigment Mutant Gunmetal by Swank, Richard T., Jiang, Shelley Y., Reddington, Madonna, Conway, James, Stephenson, Dennis, McGarry, Michael P., Novak, Edward K.

“…Gunmetal (gm/gm) is a recessively inherited mouse pigment dilution mutant that has high mortality and poor reproductive rates. In these studies, several…”
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Platelet Storage Pool Deficiency Associated With Inherited Abnormalities of the Inner Ear in the Mouse Pigment Mutants Muted and Mocha by Swank, Richard T., Reddington, Madonna, Howlett, Orla, Novak, Edward K.

“…Several inherited human syndromes have combined platelet, auditory, and/or pigment abnormalities. In the mouse the pallid pigment mutant has abnormalities of…”
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Increased Incidence and Analysis of Emperipolesis in Megakaryocytes of the Mouse Mutant Gunmetal by McGarry, Michael P., Reddington, Madonna, Jackson, Carl W., Zhen, Lijie, Novak, Edward K., Swank, Richard T.

“…Mutant gunmetal (gm/gm) mice exhibit prolonged bleeding, platelet granule defects, abnormal megakaryocyte demarcation membranes, and thrombocytopenia. The…”
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Inherited Thrombocytopenia Caused by Reduced Platelet Production in MiceWith the Gunmetal Pigment Gene Mutation by Novak, Edward K., Reddington, Madonna, Zhen, Lijie, Stenberg, Paula E., Jackson, Carl W., McGarry, Michael P., Swank, Richard T.

“…Hereditary macrothrombocytopenia and prolonged bleeding times are associated with the recessive mouse pigment dilution gene gunmetal ( gm ). Other platelet…”
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Immature Dense Granules in Platelets From Mice With Platelet Storage Pool Disease by Reddington, Madonna, Novak, Edward K., Hurley, Edward, Medda, Chitra, McGarry, Michael P., Swank, Richard T.

“…Mepacrine uptake into platelets and bone marrow mega-karyocytes was analyzed to further characterize the dense granule defects in a group of seven mouse…”
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Survival and lung pathology of mouse models of Hermansky-Pudlak syndrome and Chediak-Higashi syndrome by McGarry, M P, Reddington, M, Novak, E K, Swank, R T

“…Hermansky-Pudlak Syndrome (HPS), a recessively inherited disease in humans, affects the biosynthesis/processing of the related intracellular organelles:…”
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Inherited prolonged bleeding time and platelet storage pool deficiency in the subtle gray (sut) mouse by Swank, R T, Reddington, M, Novak, E K

“…A high proportion of mouse mutants with diluted pigmentation have severely prolonged bleeding times due to platelet storage pool deficiency. The deficiency is…”
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