Search Results - "Redda, Kinfe"

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  1. 1

    Thymoquinone Inhibition of Chemokines in TNF-α-Induced Inflammatory and Metastatic Effects in Triple-Negative Breast Cancer Cells by Adinew, Getinet M, Messeha, Samia, Taka, Equar, Mochona, Bereket, Redda, Kinfe K, Soliman, Karam F A

    “…The lack of identifiable molecular targets or biomarkers hinders the development of treatment options in triple-negative breast cancer (TNBC). However, natural…”
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  2. 2

    Design and Synthesis of Tetrahydroisoquinoline Derivatives as Anti-Angiogenesis and Anti-Cancer Agents by Gangapuram, Madhavi, Eyunni, Suresh, Zhang, Wang, Redda, Kinfe K

    Published in Anti-cancer agents in medicinal chemistry (01-01-2021)
    “…The aim of our research work is the synthesis of tetrahydroisoquinoline derivatives as anti-Angiogenesis and anti-cancer agents. Cancer is the second leading…”
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  3. 3

    Functional evaluation of synthetic flavonoids and chalcones for potential antiviral and anticancer properties by Mateeva, Nelly, Eyunni, Suresh V.K., Redda, Kinfe K., Ononuju, Ucheze, Hansberry, Tony D., Aikens, Cecilia, Nag, Anita

    Published in Bioorganic & medicinal chemistry letters (01-06-2017)
    “…[Display omitted] Flavonoids, stilbenes, and chalcones are plant secondary metabolites that often possess diverse biological activities including…”
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  4. 4

    Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel by Gangapuram, Madhavi, Mazzio, Elizabeth A., Redda, Kinfe K., Soliman, Karam F. A.

    “…The absence of chemotherapeutic target hormone receptors in breast cancer is descriptive of the commonly known triple-negative breast cancer (TNBC) subtype…”
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  5. 5

    The Antiproliferative Effects of Flavonoid MAO Inhibitors on Prostate Cancer Cells by Zarmouh, Najla O, Messeha, Samia S, Mateeva, Nelly, Gangapuram, Madhavi, Flowers, Kacy, Eyunni, Suresh V K, Zhang, Wang, Redda, Kinfe K, Soliman, Karam F A

    Published in Molecules (Basel, Switzerland) (11-05-2020)
    “…Prostate cancer (PCa) patients commonly experience clinical depression. Recent reports indicated that monoamine oxidase-A (MAO-A) levels elevate in PCa, and…”
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    Synthesis of new analogs of N-substituted(benzoylamino)-1,2,3,6-tetrahydropyridines by Gedeon, Shasline, Boyd, Laila M., Avril, Marlee, Gangapuram, Madhavi, Redda, Kinfe K., Ardley, Tiffany W.

    Published in Open Chemistry (09-04-2024)
    “…The tetrahydropyridine (THP) moiety is notably present in synthetic and natural products, playing a cardinal role in the food, cosmetic, and pharmaceutical…”
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  8. 8

    Substituted Tetrahydroisoquinolines as Microtubule-destabilizing Agents in Triple Negative Human Breast Cancer Cells by Gangapuram, Madhavi, Jean, Riccardo, Mazzio, Elizabeth, Badisa, Ramesh, Eyunni, Suresh, Goodman, Carl B, Redda, Kinfe K, Soliman, Karam F

    Published in Anticancer research (01-10-2016)
    “…Triple-negative breast cancer (TNBC) occurs at greater frequency amongst African-Americans, being characterized by the absence of estrogen receptor (ER),…”
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    Synthesis and Cytotoxic Evaluation of Pyrrole Hetarylazoles Containing Benzimidazole/Pyrazolone/1,3,4-Oxadiazole Motifs by Mochona, Bereket, Jackson, Timothy, McCauley, DeCoria, Mazzio, Elizabeth, Redda, Kinfe K.

    Published in Journal of heterocyclic chemistry (01-11-2016)
    “…Azomethine‐linked pyrrole bishetarylazoles containing benzimidazole/pyrazolone/1,3,4‐oxadiazole were synthesized in satisfactory yields. Their structures were…”
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  12. 12

    Biological evaluation of synthetic chalcone and flavone derivatives as anti-inflammatory agents by Mateeva, Nelly, Gangapuram, Madhavi, Mazzio, Elizabeth, Eyunni, Suresh, Soliman, Karam F. A., Redda, Kinfe K.

    Published in Medicinal chemistry research (01-04-2015)
    “…Flavonoids and chalcones are natural plant derived compounds with inherent therapeutic value for a range of human pathologies. In this study, a series of 24…”
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  13. 13

    Synthesis and Biological Evaluation of Substituted N-[3-(1H-Pyrrol-1-yl)methyl]-1,2,5,6-tetrahydropyridin-1-yl]benzamide/benzene Sulfonamides as Anti-Inflammatory Agents by Gangapuram, Madhavi, Mazzio, Elizabeth, Eyunni, Suresh, Soliman, Karam F. A., Redda, Kinfe K.

    Published in Archiv der Pharmazie (Weinheim) (01-05-2014)
    “…The pharmacological activities of tetrahydropyridine (THP) derivatives are dependent on the substituent ring moiety. In this study, we investigate the…”
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  14. 14

    Synthesis of substituted N-[4(5-methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-yl]benzamide/benzene sulfonamides as anti-inflammatory and anti-cancer agents by Gangapuram, Madhavi, Redda, Kinfe K.

    Published in Journal of heterocyclic chemistry (01-03-2009)
    “…Fourteen novel substituted N‐[4(5‐methyl/phenyl‐1,3,4‐oxadiazol‐2‐yl)‐3,6‐dihydropyridin‐1(2H)‐yl] benzamide/benzene sulfonamides (11a, 11b, 11c, 11d, 11e,…”
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  15. 15

    Synthesis of 2-(N-benzylpyrrolyl)-benzimidazoles using polyphosphoric acid prompted cyclocondensation by Mochona, Bereket, Le, Laine, Gangapuram, Madhavi, Mateeva, Nelly, Ardley, Tiffany, Redda, Kinfe K.

    Published in Journal of heterocyclic chemistry (01-11-2010)
    “…Synthesis of a series of 2‐substituted benzimidazoles was carried out for screening anti‐inflammatory activities. 2‐(N‐benzylpyrrolyl)‐benzimidazoles 9a, 9b,…”
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  16. 16

    Synthesis of N-Substituted Carbonylamino-1,2,3,6-tetrahydropyridines as Potential Anti-Inflammatory Agents by Ghaffari, Mohammad A., Ardley, Tiffany W., Gangapuram, Madhavi, Redda, Kinfe K.

    Published in Synthetic communications (01-01-2011)
    “…Several N-substituted carbonyl/sulfonylamino-1,2,3,6-tetrahydropyridines (5a-i and 9a, b) were synthesized via sodium borohydride reduction of the…”
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  17. 17

    Synthesis of 1-(substituted phenylcarbonyl/sulfonylamino)-1,2,3,6-tetrahydropyridine-5-carboxylic acid diethylamides as potential anti-inflammatory agents by Gangapuram, Madhavi, Redda, Kinfe K.

    Published in Journal of heterocyclic chemistry (01-05-2006)
    “…Fifteen novel 1‐(substituted phenylcarbonyl/sulfonylamino)‐1,2,3,6‐tetrahydro‐ pyridine‐5‐carboxylic acid diethylamide (7, 15) were synthesized in fair to good…”
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  18. 18

    N-(4-amino-7-nitrobenzaoxa-1,3-diazole)-substituted aza crown ethers: complexation with alkali, alkaline earth metal ions and ammonium by Mateeva, Nelly N., Deiab, Shihab D., Archibong, Edikan E., Jackson, Mercedes, Mochona, Bereket, Gangapuram, Madhavi, Redda, Kinfe K.

    “…Three novel aza-crown ether derivatives incorporating 4-amino-7-nitrobenzaoxa-1,3-diazole (NBD) chromophore were synthesized and their structure confirmed by 1…”
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  19. 19

    Abstract 22: Design and synthesis of substituted tetrahydroisoquinoline derivatives as anti-angiogenic and anti-breast cancer agents by Redda, Kinfe Ken, Gangapuram, Madhavi, Eyuinni, Suresh

    Published in Cancer research (Chicago, Ill.) (01-07-2019)
    “…Abstract Angiogenesis is the formation of new blood vessels and plays a critical role in the development, invasion and metastasis of breast cancer…”
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    Conformational analysis and molecular properties of N-(substituted phenyl-carbonylamino)-4-(1-hydroxymethylphenyl)-1,2,3,6-tetrahydropyridines by Okoroa, Cosmas O, Wilsonb, Tiffany L, Redda, Kinfe K

    Published in Current medicinal chemistry (01-02-2003)
    “…The three-dimensional structures of active derivatives of N-(substitutedphenylcarbonylamino)-4-(1-hydroxymethylphenyl)-1,2,3,6-tetrahydropyri-dines, which have…”
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