Search Results - "Redda, Kinfe"
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Thymoquinone Inhibition of Chemokines in TNF-α-Induced Inflammatory and Metastatic Effects in Triple-Negative Breast Cancer Cells
Published in International journal of molecular sciences (01-06-2023)“…The lack of identifiable molecular targets or biomarkers hinders the development of treatment options in triple-negative breast cancer (TNBC). However, natural…”
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Design and Synthesis of Tetrahydroisoquinoline Derivatives as Anti-Angiogenesis and Anti-Cancer Agents
Published in Anti-cancer agents in medicinal chemistry (01-01-2021)“…The aim of our research work is the synthesis of tetrahydroisoquinoline derivatives as anti-Angiogenesis and anti-cancer agents. Cancer is the second leading…”
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3
Functional evaluation of synthetic flavonoids and chalcones for potential antiviral and anticancer properties
Published in Bioorganic & medicinal chemistry letters (01-06-2017)“…[Display omitted] Flavonoids, stilbenes, and chalcones are plant secondary metabolites that often possess diverse biological activities including…”
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4
Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel
Published in International journal of molecular sciences (19-07-2021)“…The absence of chemotherapeutic target hormone receptors in breast cancer is descriptive of the commonly known triple-negative breast cancer (TNBC) subtype…”
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5
The Antiproliferative Effects of Flavonoid MAO Inhibitors on Prostate Cancer Cells
Published in Molecules (Basel, Switzerland) (11-05-2020)“…Prostate cancer (PCa) patients commonly experience clinical depression. Recent reports indicated that monoamine oxidase-A (MAO-A) levels elevate in PCa, and…”
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Mentoring Minority Cancer Researchers of Tomorrow: Comparison of the Face-to-Face, Virtual, and Hybrid Training Methods of the CaRE2 Summer Cancer Research Education and Training Program
Published in Journal of cancer education (01-08-2024)“…In our previous publication, we reported a framework to develop an undergraduate cancer research training program at Florida A&M University (FAMU) under the…”
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Synthesis of new analogs of N-substituted(benzoylamino)-1,2,3,6-tetrahydropyridines
Published in Open Chemistry (09-04-2024)“…The tetrahydropyridine (THP) moiety is notably present in synthetic and natural products, playing a cardinal role in the food, cosmetic, and pharmaceutical…”
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Substituted Tetrahydroisoquinolines as Microtubule-destabilizing Agents in Triple Negative Human Breast Cancer Cells
Published in Anticancer research (01-10-2016)“…Triple-negative breast cancer (TNBC) occurs at greater frequency amongst African-Americans, being characterized by the absence of estrogen receptor (ER),…”
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9
Research Infrastructure Core Facilities at Research Centers in Minority Institutions: Part I-Research Resources Management, Operation, and Best Practices
Published in International journal of environmental research and public health (17-12-2022)“…Funded by the National Institutes of Health (NIH), the Research Centers in Minority Institutions (RCMI) Program fosters the development and implementation of…”
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Developing a Novel Framework for an Undergraduate Cancer Research Education and Engagement Program for Underrepresented Minority Students: the Florida-California CaRE2 Research Education Core (REC) Training Program
Published in Journal of cancer education (01-10-2021)“…Lack of substantive research experiences and technical skills mentoring during undergraduate studies leaves many underrepresented minority (URM) students…”
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11
Synthesis and Cytotoxic Evaluation of Pyrrole Hetarylazoles Containing Benzimidazole/Pyrazolone/1,3,4-Oxadiazole Motifs
Published in Journal of heterocyclic chemistry (01-11-2016)“…Azomethine‐linked pyrrole bishetarylazoles containing benzimidazole/pyrazolone/1,3,4‐oxadiazole were synthesized in satisfactory yields. Their structures were…”
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Biological evaluation of synthetic chalcone and flavone derivatives as anti-inflammatory agents
Published in Medicinal chemistry research (01-04-2015)“…Flavonoids and chalcones are natural plant derived compounds with inherent therapeutic value for a range of human pathologies. In this study, a series of 24…”
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13
Synthesis and Biological Evaluation of Substituted N-[3-(1H-Pyrrol-1-yl)methyl]-1,2,5,6-tetrahydropyridin-1-yl]benzamide/benzene Sulfonamides as Anti-Inflammatory Agents
Published in Archiv der Pharmazie (Weinheim) (01-05-2014)“…The pharmacological activities of tetrahydropyridine (THP) derivatives are dependent on the substituent ring moiety. In this study, we investigate the…”
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Synthesis of substituted N-[4(5-methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-yl]benzamide/benzene sulfonamides as anti-inflammatory and anti-cancer agents
Published in Journal of heterocyclic chemistry (01-03-2009)“…Fourteen novel substituted N‐[4(5‐methyl/phenyl‐1,3,4‐oxadiazol‐2‐yl)‐3,6‐dihydropyridin‐1(2H)‐yl] benzamide/benzene sulfonamides (11a, 11b, 11c, 11d, 11e,…”
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Synthesis of 2-(N-benzylpyrrolyl)-benzimidazoles using polyphosphoric acid prompted cyclocondensation
Published in Journal of heterocyclic chemistry (01-11-2010)“…Synthesis of a series of 2‐substituted benzimidazoles was carried out for screening anti‐inflammatory activities. 2‐(N‐benzylpyrrolyl)‐benzimidazoles 9a, 9b,…”
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16
Synthesis of N-Substituted Carbonylamino-1,2,3,6-tetrahydropyridines as Potential Anti-Inflammatory Agents
Published in Synthetic communications (01-01-2011)“…Several N-substituted carbonyl/sulfonylamino-1,2,3,6-tetrahydropyridines (5a-i and 9a, b) were synthesized via sodium borohydride reduction of the…”
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17
Synthesis of 1-(substituted phenylcarbonyl/sulfonylamino)-1,2,3,6-tetrahydropyridine-5-carboxylic acid diethylamides as potential anti-inflammatory agents
Published in Journal of heterocyclic chemistry (01-05-2006)“…Fifteen novel 1‐(substituted phenylcarbonyl/sulfonylamino)‐1,2,3,6‐tetrahydro‐ pyridine‐5‐carboxylic acid diethylamide (7, 15) were synthesized in fair to good…”
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N-(4-amino-7-nitrobenzaoxa-1,3-diazole)-substituted aza crown ethers: complexation with alkali, alkaline earth metal ions and ammonium
Published in Journal of Inclusion Phenomena and Macrocyclic Chemistry (01-12-2010)“…Three novel aza-crown ether derivatives incorporating 4-amino-7-nitrobenzaoxa-1,3-diazole (NBD) chromophore were synthesized and their structure confirmed by 1…”
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Abstract 22: Design and synthesis of substituted tetrahydroisoquinoline derivatives as anti-angiogenic and anti-breast cancer agents
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Angiogenesis is the formation of new blood vessels and plays a critical role in the development, invasion and metastasis of breast cancer…”
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20
Conformational analysis and molecular properties of N-(substituted phenyl-carbonylamino)-4-(1-hydroxymethylphenyl)-1,2,3,6-tetrahydropyridines
Published in Current medicinal chemistry (01-02-2003)“…The three-dimensional structures of active derivatives of N-(substitutedphenylcarbonylamino)-4-(1-hydroxymethylphenyl)-1,2,3,6-tetrahydropyri-dines, which have…”
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