Search Results - "Reczek, Elizabeth. E"

The NF1 Tumor Suppressor Critically Regulates TSC2 and mTOR by Johannessen, Cory M., Reczek, Elizabeth E., James, Marianne F., Brems, Hilde, Legius, Eric, Cichowski, Karen, Cantley, Lewis C.

“…Loss-of-function mutations in the NF1 tumor suppressor gene underlie the familial cancer syndrome neurofibromatosis type I (NF1). The NF1-encoded protein,…”
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Restoration of p53 function leads to tumour regression in vivo by Jacks, Tyler, Ventura, Andrea, Kirsch, David G, McLaughlin, Margaret E, Tuveson, David A, Grimm, Jan, Lintault, Laura, Newman, Jamie, Reczek, Elizabeth E, Weissleder, Ralph

“…Tumorigenesis is a multi-step process that requires activation of oncogenes and inactivation of tumour suppressor genes. Mouse models of human cancers have…”
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An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-[kappa]B by Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, Mclaughlin, Sara K, Reczek, Elizabeth E, De Raedt, Thomas, Guney, Isil, Strochlic, David E, Macconaill, Laura E, Beroukhim, Rameen, Bronson, Roderick T, Ryeom, Sandra, Hahn, William C, Loda, Massimo, Cichowski, Karen

“…Metastasis is responsible for the majority of prostate cancer-related deaths; however, little is known about the molecular mechanisms that underlie this…”
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An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB by Cichowski, Karen, Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K, Reczek, Elizabeth E, De Raedt, Thomas, Guney, Isil, Strochlic, David E, MacConaill, Laura E, Beroukhim, Rameen, Bronson, Roderick T, Ryeom, Sandra, Hahn, William C, Loda, Massimo

“…Metastasis is a fatal complication of prostate cancer, but its mechanisms remain largely unknown. In this report, the authors identify a signaling pathway…”
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Author Correction: An oncogene–tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB by Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara. K, Reczek, Elizabeth. E, De. Raedt, Thomas, Guney, Isil, Strochlic, David. E, MacConaill, Laura. E, Beroukhim, Rameen, Bronson, Roderick. T, Ryeom, Sandra, Hahn, William. C, Loda, Massimo, Cichowski, Karen

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A negative feedback signaling network underlies oncogene-induced senescence by Courtois-Cox, Stéphanie, Genther Williams, Sybil M., Reczek, Elizabeth E., Johnson, Bryan W., McGillicuddy, Lauren T., Johannessen, Cory M., Hollstein, Pablo E., MacCollin, Mia, Cichowski, Karen

“…Oncogene-induced senescence functions to limit tumor development. However, a complete understanding of the signals that trigger this type of senescence is…”
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Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization by Acquaye-Seedah, Edith, Reczek, Elizabeth E, Russell, Hugh H, DiVenere, Andrea M, Sandman, Sara O, Collins, Joseph H, Stein, Caitlin A, Whitehead, Timothy A, Maynard, Jennifer A

“…Despite high vaccination rates, the incidence of whooping cough has steadily been increasing in developing countries for several decades. The current acellular…”
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TORC1 Is Essential for NF1-Associated Malignancies by Johannessen, Cory M., Johnson, Bryan W., Williams, Sybil M. Genther, Chan, Annie W., Reczek, Elizabeth E., Lynch, Ryan C., Rioth, Matthew J., McClatchey, Andrea, Ryeom, Sandra, Cichowski, Karen

“…Inactivating mutations in NF1 underlie the prevalent familial cancer syndrome neurofibromatosis type 1 [1]. The NF1-encoded protein is a Ras GTPase-activating…”
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PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family by Attardi, L D, Reczek, E E, Cosmas, C, Demicco, E G, McCurrach, M E, Lowe, S W, Jacks, T

“…The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response to cellular stress. Mouse embryo fibroblasts (MEFs) provide a powerful…”
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Non-viral adeno-associated virus-based platform for stable expression of antibody combination therapeutics: Non-viral adeno-associated virus-based platform for stable expression of antibody combination therapeutics by Wilmes, Gwendolyn M, Carey, Kimberly L, Hicks, Stuart W, Russell, Hugh H, Stevenson, Jesse A, Kocjan, Paulina, Lutz, Stephen R, Quesenberry, Rachel S, Shulga-Morskoy, Sergey V, Lewis, Megan E, Clark, Ethan, Medik, Violetta, Cooper, Anthony B, Reczek, Elizabeth E

“…Antibody combination therapeutics (ACTs) are polyvalent biopharmaceuticals that are uniquely suited for the control of complex diseases, including antibiotic…”
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Multiple response elements and differential p53 binding control Perp expression during apoptosis by Reczek, Elizabeth E, Flores, Elsa R, Tsay, Alice S, Attardi, Laura D, Jacks, Tyler

“…The p53 tumor suppressor gene responds to cellular stress by activating either cell cycle arrest or apoptosis. A growing number of target genes involved in…”
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An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and NF-κB by Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K., Reczek, Elizabeth E., De Raedt, Thomas, Guney, Isil, Strochlic, David E., Laura, E., Beroukhim, Rameen, Bronson, Roderick T., Ryeom, Sandra, Hahn, William C., Loda, Massimo, Cichowski, Karen

“…Metastasis is responsible for the majority of prostate cancer-related deaths; however, little is known about the molecular mechanisms that underlie this…”
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Multiple Response Elements and Differential p53 Binding Control Perp Expression During Apoptosis1 1 Anna Fuller Fund (E. E. R.), Leukemia and Lymphoma Society of America (E. R. F.), Damon Runyon Cancer Research Foundation (L. D. A.), and NIH and Howard Hughes Medical Institute (T. J.) by Elizabeth E. Reczek, Elsa R. Flores, Alice S. Tsay, Laura D. Attardi, Tyler Jacks

“…The p53 tumor suppressor gene responds to cellular stress by activating either cell cycle arrest or apoptosis. A growing number of target genes involved in…”
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An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB by Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K, Reczek, Elizabeth E, De Raedt, Thomas, Guney, Isil, Strochlic, David E, Macconaill, Laura E, Beroukhim, Rameen, Bronson, Roderick T, Ryeom, Sandra, Hahn, William C, Loda, Massimo, Cichowski, Karen

“…Metastasis is responsible for the majority of prostate cancer-related deaths; however, little is known about the molecular mechanisms that underlie this…”
Get full text