Search Results - "Rector, Jonah"
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A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation
Published in Immunity (Cambridge, Mass.) (09-02-2021)“…The vaccine strain against smallpox, vaccinia virus (VACV), is highly immunogenic yet causes relatively benign disease. These attributes are believed to be…”
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Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation
Published in Journal of medicinal chemistry (26-09-2019)“…Chemical control of cullin neddylation is attracting increased attention based largely on the successes of the NEDD8-activating enzyme (E1) inhibitor…”
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Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents
Published in Journal of medicinal chemistry (26-08-2021)“…Leishmaniasis, a disease caused by protozoa of the species, afflicts roughly 12 million individuals worldwide. Most existing drugs for leishmaniasis are toxic,…”
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Journal Article