Search Results - "Reconditi, M."
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Structural changes in myosin motors and filaments during relaxation of skeletal muscle
Published in The Journal of physiology (15-09-2009)“…Structural changes in myosin motors and filaments during relaxation from short tetanic contractions of intact single fibres of frog tibialis anterior muscles…”
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Temperature dependence of the force-generating process in single fibres from frog skeletal muscle
Published in The Journal of physiology (15-05-2003)“…Generation of force and shortening in striated muscle is due to the cyclic interactions of the globular portion (the head) of the myosin molecule, extending…”
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Structural changes in the myosin filament and cross-bridges during active force development in single intact frog muscle fibres: stiffness and X-ray diffraction measurements
Published in The Journal of physiology (15-12-2006)“…Structural and mechanical changes occurring in the myosin filament and myosin head domains during the development of the isometric tetanus have been…”
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Mechanics of myosin function in white muscle fibres of the dogfish, Scyliorhinus canicula
Published in The Journal of physiology (01-04-2012)“…Key points • Muscle force and shortening are generated by a structural change called the working stroke in myosin motor proteins that cross‐link the myosin…”
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Interference Fine Structure and Sarcomere Length Dependence of the Axial X-Ray Pattern from Active Single Muscle Fibers
Published in Proceedings of the National Academy of Sciences - PNAS (20-06-2000)“…Axial x-ray diffraction patterns from single intact fibers of frog skeletal muscle were recorded by using a highly collimated x-ray beam at the European…”
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Reverse actin sliding triggers strong myosin binding that moves tropomyosin
Published in Proceedings of the National Academy of Sciences - PNAS (29-07-2008)“…Actin/myosin interactions in vertebrate striated muscles are believed to be regulated by the "steric blocking" mechanism whereby the binding of calcium to the…”
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The structural basis of the increase in isometric force production with temperature in frog skeletal muscle
Published in The Journal of physiology (01-09-2005)“…X-ray diffraction patterns were recorded from isolated single fibres of frog skeletal muscle during isometric contraction at temperatures between 0 and 17°C…”
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A combined mechanical and X-ray diffraction study of stretch potentiation in single frog muscle fibres
Published in The Journal of physiology (01-08-2000)“…The nature of the force ( T ) response during and after steady lengthening has been investigated in tetanized single muscle fibres from Rana temporaria (4 °C;…”
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The Conformation of Myosin Head Domains in Rigor Muscle Determined by X-Ray Interference
Published in Biophysical journal (01-08-2003)“…In the absence of adenosine triphosphate, the head domains of myosin cross-bridges in muscle bind to actin filaments in a rigor conformation that is expected…”
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Cross-bridge detachment and attachment following a step stretch imposed on active single frog muscle fibres
Published in The Journal of physiology (01-01-1997)“…1. The time course of cross-bridge detachment-attachment following a step stretch was determined in single frog muscle fibres (at 4 degrees (1 and 2.1 microns…”
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X-ray Interference Studies of Crossbridge Action in Muscle Contraction: Evidence from Quick Releases
Published in Journal of molecular biology (03-11-2006)“…We have used a high-resolution small angle X-ray scattering system, together with a high-performance CCD camera, on the BioCAT beamline at the APS synchrotron…”
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The myosin motor in muscle generates a smaller and slower working stroke at higher load
Published in Nature (01-04-2004)“…Muscle contraction is driven by the motor protein myosin II, which binds transiently to an actin filament, generates a unitary filament displacement or…”
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Mechanism of force generation by myosin heads in skeletal muscle
Published in Nature (London) (07-02-2002)“…Muscles generate force and shortening in a cyclical interaction between the myosin head domains projecting from the myosin filaments and the adjacent actin…”
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The mechanism of the force response to stretch in human skinned muscle fibres with different myosin isoforms
Published in The Journal of physiology (15-01-2004)“…Force enhancement during lengthening of an active muscle, a condition that normally occurs during locomotion in vivo , is attributed to recruitment of myosin…”
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The Stiffness of Skeletal Muscle in Isometric Contraction and Rigor: The Fraction of Myosin Heads Bound to Actin
Published in Biophysical journal (01-05-1998)“…Step changes in length (between −3 and +5nm per half-sarcomere) were imposed on isolated muscle fibers at the plateau of an isometric tetanus (tension T0) and…”
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Elastic bending and active tilting of myosin heads during muscle contraction
Published in Nature (London) (26-11-1998)“…Muscle contraction is driven by a change in shape of the myosin head region that links the actin and myosin filaments,. Tilting of the light-chain domain of…”
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Conformation of the myosin motor during force generation in skeletal muscle
Published in Nature structural biology (01-06-2000)“…Myosin motors drive muscle contraction, cytokinesis and cell locomotion, and members of the myosin superfamily have been implicated in an increasingly diverse…”
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X-ray diffraction studies of the contractile mechanism in single muscle fibres
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-12-2004)“…The molecular mechanism of muscle contraction was investigated in intact muscle fibres by X–ray diffraction. Changes in the intensities of the axial X–ray…”
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Structure-Function Relation of the Myosin Motor in Striated Muscle
Published in Annals of the New York Academy of Sciences (01-06-2005)“…: Force and shortening in striated muscle are driven by a structural working stroke in the globular portion of the myosin molecules—the myosin head—that…”
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