Search Results - "Recknor, Chris"
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Effects of intravenous zoledronic acid plus subcutaneous teriparatide [rhPTH(1–34)] in postmenopausal osteoporosis
Published in Journal of bone and mineral research (01-03-2011)“…Clinical data suggest concomitant therapy with bisphosphonates and parathyroid hormone (PTH) may blunt the anabolic effect of PTH; rodent models suggest that…”
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Zoledronic Acid and Clinical Fractures and Mortality after Hip Fracture
Published in The New England journal of medicine (01-11-2007)“…Mortality is increased in the year after a hip fracture, and strategies that improve the outcome are needed. This randomized, double-blind, placebo-controlled…”
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Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study
Published in Journal of rheumatology (01-03-2008)“…OBJECTIVE: An effective and well tolerated intravenous (IV) bisphosphonate could provide a new treatment method for patients with osteoporosis. The Dosing…”
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Hospitalization in High Fracture Risk Older Adults with Osteoporosis Using the Safe Functional Motion Test: A Longitudinal Analysis
Published in Gerontology and geriatric medicine (2021)“…The Safe Functional Motion Test (SFM-5) is a five item performance based clinical assessment tool quantifying habitual daily movement that may increase the…”
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Antifracture Efficacy and Reduction of Mortality in Relation to Timing of the First Dose of Zoledronic Acid After Hip Fracture
Published in Journal of bone and mineral research (01-07-2009)“…Annual infusions of zoledronic acid (5 mg) significantly reduced the risk of vertebral, hip, and nonvertebral fractures in a study of postmenopausal women with…”
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Bimagrumab to improve recovery after hip fracture in older adults: a multicentre, double-blind, randomised, parallel-group, placebo-controlled, phase 2a/b trial
Published in The Lancet. Healthy longevity (01-05-2021)“…Older adult patients (ie, those aged ≥60 years) undergoing surgery for hip fracture repair frequently experience loss of muscle mass and strength due to poor…”
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Influence of subject discontinuation on long-term nonvertebral fracture rate in the denosumab FREEDOM Extension study
Published in BMC musculoskeletal disorders (27-04-2017)“…Denosumab treatment for up to 8 years in the FREEDOM study and Extension was associated with low fracture incidence. It was not clear whether subjects who…”
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Baseline Glucocorticoid Dose and Bone Mineral Density Response with Teriparatide or Alendronate Therapy in Patients with Glucocorticoid-induced Osteoporosis
Published in Journal of rheumatology (01-01-2010)“…Objective. This post-hoc analysis studied the effect of baseline glucocorticoid dose on the 18-month bone mineral density (BMD) response to teriparatide 20 μ…”
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Scores on the safe functional motion test are associated with prevalent fractures and fall history
Published in Physiotherapy Canada (2013)“…The Safe Functional Motion test (SFM) was developed to measure observed body mechanics and functional motion associated with spine load, balance, strength, and…”
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Effects of Romosozumab Compared With Teriparatide on Bone Density and Mass at the Spine and Hip in Postmenopausal Women With Low Bone Mass
Published in Journal of bone and mineral research (01-01-2017)“…ABSTRACT Romosozumab, a monoclonal antibody that binds sclerostin, has a dual effect on bone by increasing bone formation and reducing bone resorption, and…”
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Efficacy and safety of transdermal abaloparatide in postmenopausal women with osteoporosis: a randomized study
Published in Journal of bone and mineral research (01-10-2023)“…Anabolic therapies, recommended for patients at very high fracture risk, are administered subcutaneously (SC). The objective of this study was to evaluate…”
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Early Effects of Abaloparatide on Bone Formation and Resorption Indices in Postmenopausal Women With Osteoporosis
Published in Journal of bone and mineral research (01-04-2021)“…Anabolic osteoporosis drugs improve bone mineral density by increasing bone formation. The objective of this study was to evaluate the early effects of…”
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The Efficacy and Safety of Abaloparatide‐SC in Men With Osteoporosis: A Randomized Clinical Trial
Published in Journal of bone and mineral research (01-12-2022)“…ABSTRACT Abaloparatide significantly increased bone mineral density (BMD) in women with postmenopausal osteoporosis and decreased risk of vertebral,…”
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Zoledronic acid for prevention and treatment of osteoporosis
Published in Expert opinion on pharmacotherapy (01-04-2011)“…Osteoporosis (OP) is associated with a high risk of fracture and disability and with substantial medical costs. This paper is a review of the intravenous…”
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Denosumab Compared With Ibandronate in Postmenopausal Women Previously Treated With Bisphosphonate Therapy: A Randomized Open-Label Trial
Published in Obstetrics and gynecology (New York. 1953) (01-06-2013)“…To compare the efficacy and safety of denosumab to ibandronate in postmenopausal women with low bone mineral density (BMD) previously treated with a…”
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Romosozumab Enhances Vertebral Bone Structure in Women With Low Bone Density
Published in Journal of bone and mineral research (01-02-2022)“…ABSTRACT Romosozumab monoclonal antibody treatment works by binding sclerostin and causing rapid stimulation of bone formation while decreasing bone…”
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Zoledronic Acid for the Prevention of Bone Loss in Postmenopausal Women With Low Bone Mass: A Randomized Controlled Trial
Published in Obstetrics and gynecology (New York. 1953) (01-11-2009)“…To evaluate the efficacy of zoledronic acid in the prevention of bone loss in postmenopausal women with low bone mass. In this 2-year, randomized, multicenter,…”
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Femoral and Vertebral Strength Improvements in Postmenopausal Women With Osteoporosis Treated With Denosumab
Published in Journal of bone and mineral research (01-01-2014)“…ABSTRACT In the randomized, placebo‐controlled FREEDOM study of women aged 60 to 90 years with postmenopausal osteoporosis, treatment with denosumab once every…”
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Bimagrumab vs Optimized Standard of Care for Treatment of Sarcopenia in Community-Dwelling Older Adults: A Randomized Clinical Trial
Published in JAMA network open (01-10-2020)“…The potential benefit of novel skeletal muscle anabolic agents to improve physical function in people with sarcopenia and other muscle wasting diseases is…”
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