Search Results - "Recknagel, Stefan"

Fracture healing under healthy and inflammatory conditions by Claes, Lutz, Recknagel, Stefan, Ignatius, Anita

“…The interplay between the cells that regulate bone architecture and the immune system is increasingly recognized. In this Review, as well as providing an…”
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Systemic inflammation induced by a thoracic trauma alters the cellular composition of the early fracture callus by Recknagel, Stefan, Bindl, Ronny, Brochhausen, Christoph, Göckelmann, Melanie, Wehner, Tim, Schoengraf, Philipp, Huber-Lang, Markus, Claes, Lutz, Ignatius, Anita

“…We recently demonstrated that a blunt chest trauma, a strong inducer of the posttraumatic systemic inflammatory response and one of the most critical injuries…”
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Complement C3 and C5 deficiency affects fracture healing by Ehrnthaller, Christian, Huber-Lang, Markus, Nilsson, Per, Bindl, Ronny, Redeker, Simon, Recknagel, Stefan, Rapp, Anna, Mollnes, Tom, Amling, Michael, Gebhard, Florian, Ignatius, Anita

“…There is increasing evidence that complement may play a role in bone development. Our previous studies demonstrated that the key complement receptor C5aR was…”
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Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice by Rapp, Anna E, Bindl, Ronny, Recknagel, Stefan, Erbacher, Annika, Müller, Ingo, Schrezenmeier, Hubert, Ehrnthaller, Christian, Gebhard, Florian, Ignatius, Anita

“…Following bone fracture, the repair process starts with an inflammatory reaction at the fracture site. Fracture healing is disturbed when the initial…”
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Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β by Ignatius, Anita, Schoengraf, Philipp, Kreja, Ludwika, Liedert, Astrid, Recknagel, Stefan, Kandert, Sebastian, Brenner, Rolf E., Schneider, Marion, Lambris, John D., Huber-Lang, Markus

“…There is a tight interaction of the bone and the immune system. However, little is known about the relevance of the complement system, an important part of…”
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Temporal delimitation of the healing phases via monitoring of fracture callus stiffness in rats by Wehner, Tim, Gruchenberg, Katharina, Bindl, Ronny, Recknagel, Stefan, Steiner, Malte, Ignatius, Anita, Claes, Lutz

“…ABSTRACT The healing process consists of at least three phases: inflammatory, repair, and remodeling phase. Because callus stiffness correlates with the…”
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The Anaphylatoxin Receptor C5aR Is Present During Fracture Healing in Rats and Mediates Osteoblast Migration In Vitro by IGNATIUS, Anita, EHRNTHALLER, Christian, LAMBRIS, John D, HUBER-LANG, Markus, BRENNER, Rolf E, KREJA, Ludwika, SCHOENGRAF, Philipp, LISSON, Patricia, BLAKYTNY, Robert, RECKNAGEL, Stefan, CLAES, Lutz, GEBHARD, Florian

“…There is evidence that complement components regulate cytokine production in osteoblastic cells, induce cell migration in mesenchymal stem cells, and play a…”
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Experimental blunt chest trauma impairs fracture healing in rats by Recknagel, Stefan, Bindl, Ronny, Kurz, Julian, Wehner, Tim, Ehrnthaller, Christian, Knöferl, Markus Werner, Gebhard, Florian, Huber-Lang, Markus, Claes, Lutz, Ignatius, Anita

“…In poly‐traumatic patients a blunt chest trauma is an important trigger of the posttraumatic systemic inflammatory response. There is clinical evidence that…”
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C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing by Recknagel, Stefan, Bindl, Ronny, Kurz, Julian, Wehner, Tim, Schoengraf, Philipp, Ehrnthaller, Christian, Qu, Hongchang, Gebhard, Florian, Huber-Lang, Markus, Lambris, John D., Claes, Lutz, Ignatius, Anita

“…Confirming clinical evidence, we recently demonstrated that a blunt chest trauma considerably impaired fracture healing in rats, possibly via the interaction…”
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Temporal delimitation of the healing phases via monitoring of fracture callus stiffness in rats: MONITORING RAT FRACTURE CALLUS STIFFNESS by Wehner, Tim, Gruchenberg, Katharina, Bindl, Ronny, Recknagel, Stefan, Steiner, Malte, Ignatius, Anita, Claes, Lutz

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INFLUENCE OF TEST CONDITIONS ON THE STIFFNESS OF RAT FRACTURE CALLUS by Wehner, Tim, Recknagel, Stefan, Steiner, Malte, Ignatius, Anita, Claes, Lutz

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Does complement play a role in bone development and regeneration? by Schoengraf, Philipp, Lambris, John D, Recknagel, Stefan, Kreja, Ludwika, Liedert, Astrid, Brenner, Rolf E, Huber-Lang, Markus, Ignatius, Anita

“…Abstract The skeletal and the immune system are not two independent systems, rather, there are multifaceted and complex interactions between the different cell…”
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Conversion from external fixator to intramedullary nail causes a second hit and impairs fracture healing in a severe trauma model by Recknagel, Stefan, Bindl, Ronny, Wehner, Tim, Göckelmann, Melanie, Wehrle, Esther, Gebhard, Florian, Huber-Lang, Markus, Claes, Lutz, Ignatius, Anita

“…In poly‐traumatic patients, second hits are known to potentiate the posttraumatic systemic inflammatory response, thus increasing the risk of multi‐organ…”
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THE INFLAMMATORY PHASE OF BONE HEALING IS INFLUENCED BY THE FIXATION STABILITY by Recknagel, Stefan, Bindl, Ronny, Wehner, Tim, Brochhausen, Christoph, Huber-Lang, Markus, Claes, Lutz, Ignatius, Anita

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The effect of both a thoracic trauma and a soft-tissue trauma on fracture healing in a rat model by Claes, Lutz, Ignatius, Anita, Lechner, Raimund, Gebhard, Florian, Kraus, Michael, Baumgärtel, Stefan, Recknagel, Stefan, Krischak, Gert D

“…Background and purpose There is some clinical evidence that fracture healing is impaired in multiply injured patients. Nothing is known, however, about the…”
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Ultrathin sP(EO-stat-PO) hydrogel coatings are biocompatible and preserve functionality of surface bound growth factors in vivo by Neuerburg, Carl, Recknagel, Stefan, Fiedler, Jörg, Groll, Jürgen, Moeller, Martin, Bruellhoff, Kristina, Reichel, Heiko, Ignatius, Anita, Brenner, Rolf E.

“…Hydrogel coatings prepared from reactive star shaped polyethylene oxide based prepolymers (NCO-sP(EO-stat-PO)) minimize unspecific protein adsorption in vitro,…”
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Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1 Delta b by Ignatius, Anita, Schoengraf, Philipp, Kreja, Ludwika, Liedert, Astrid, Recknagel, Stefan, Kandert, Sebastian, Brenner, Rolf E, Schneider, Marion, Lambris, John D, Huber-Lang, Markus

“…There is a tight interaction of the bone and the immune system. However, little is known about the relevance of the complement system, an important part of…”
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Fracture Healing Is Delayed in Immunodeficient NOD/scid-[character removed]IL2R[gamma][character removed]cnull Mice: e0147465 by Rapp, Anna E, Bindl, Ronny, Recknagel, Stefan, Erbacher, Annika, Mueller, Ingo, Schrezenmeier, Hubert, Ehrnthaller, Christian, Gebhard, Florian, Ignatius, Anita

“…Following bone fracture, the repair process starts with an inflammatory reaction at the fracture site. Fracture healing is disturbed when the initial…”
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The role of complement in bone healing: Fracture healing in C3 and C5-deficient mice by Ehrnthaller, Christian M, Huber-Lang, Markus, Recknagel, Stefan, Bindl, Ronny, Redeker, Simon, Rapp, Anna, Gebhard, Florian, Ignatius, Anita

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Micronuclei induced by 2-chlorobenzylidene malonitrile contain single chromosomes as demonstrated by the combined use of flow cytometry and immunofluorescent staining with anti-kinetochore antibodies by Nüsse, M, Recknagel, S, Beisker, W

“…The effects of the tear gas 2-chlorobenzylidene malonitrile (CS) on micronucleus induction and cell cycle kinetics were studied in Chinese hamster and Ehrlich…”
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