Search Results - "Reckman, Yolan J"

Circular RNAs open a new chapter in cardiovascular biology by Aufiero, Simona, Reckman, Yolan J., Pinto, Yigal M., Creemers, Esther E.

“…Circular RNAs (circRNAs) are emerging as a new class of non-coding RNA molecules. This unusual class of RNA species is generated by a back-splicing event of…”
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RBM20 Regulates Circular RNA Production From the Titin Gene by Khan, Mohsin A.F, Reckman, Yolan J, Aufiero, Simona, van den Hoogenhof, Maarten M.G, van der Made, Ingeborg, Beqqali, Abdelaziz, Koolbergen, Dave R, Rasmussen, Torsten B, van der Velden, Jolanda, Creemers, Esther E, Pinto, Yigal M

“…RATIONALE:RNA-binding motif protein 20 (RBM20) is essential for normal splicing of many cardiac genes, and loss of RBM20 causes dilated cardiomyopathy. Given…”
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circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs by Aufiero, Simona, Reckman, Yolan J, Tijsen, Anke J, Pinto, Yigal M, Creemers, Esther E

“…Circular RNAs (circRNAs) are a newly appreciated class of non-coding RNA molecules. Numerous tools have been developed for the detection of circRNAs, however…”
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Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons by Aufiero, Simona, van den Hoogenhof, Maarten M G, Reckman, Yolan J, Beqqali, Abdelaziz, van der Made, Ingeborg, Kluin, Jolanda, Khan, Mohsin A F, Pinto, Yigal M, Creemers, Esther E

“…Circular RNAs (circRNAs) are a relatively new class of RNA molecules, and knowledge about their biogenesis and function is still in its infancy. It was…”
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Titin Circular RNAs Create a Back-Splice Motif Essential for SRSF10 Splicing by Tijsen, Anke J., Cócera Ortega, Lucía, Reckman, Yolan J., Zhang, Xiaolei, van der Made, Ingeborg, Aufiero, Simona, Li, Jiuru, Kamps, Selina C., van den Bout, Anouk, Devalla, Harsha D., van Spaendonck-Zwarts, Karin Y., Engelhardt, Stefan, Gepstein, Lior, Ware, James S., Pinto, Yigal M.

“…TTN (Titin), the largest protein in humans, forms the molecular spring that spans half of the sarcomere to provide passive elasticity to the cardiomyocyte…”
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Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure by Raso, Andrea, Dirkx, Ellen, Philippen, Leonne E., Fernandez-Celis, Amaya, De Majo, Federica, Sampaio-Pinto, Vasco, Sansonetti, Marida, Juni, Rio, el Azzouzi, Hamid, Calore, Martina, Bitsch, Nicole, Olieslagers, Servé, Oerlemans, Martinus I.F.J., Huibers, Manon M., de Weger, Roel A., Reckman, Yolan J., Pinto, Yigal M., Zentilin, Lorena, Zacchigna, Serena, Giacca, Mauro, da Costa Martins, Paula A., López-Andrés, Natalia, De Windt, Leon J.

“…Heart failure is preceded by ventricular remodeling, changes in left ventricular mass, and myocardial volume after alterations in loading conditions…”
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Circulating Circles Predict Postoperative Atrial Fibrillation by Reckman, Yolan J., Creemers, Esther E.

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Formins Emerge as a Cause of Hypertrophic Cardiomyopathy: New Genes for Thick Hearts by Pinto, Yigal M., Reckman, Yolan J.

“…[Display omitted]…”
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A comparison of myocardial magnetic resonance extracellular volume mapping at 3 T against histology of tissue collagen in severe aortic valve stenosis and obstructive hypertrophic cardiomyopathy by Bakermans, Adrianus J., Kouwenhoven, Merel, de Vos, Judith, de Vries, Dylan K., Reckman, Yolan J., Farag, Emile S., Koolbergen, David R., Kluin, Jolanda, Nederveen, Aart J., Strijkers, Gustav J., Boekholdt, S. Matthijs

“…Objective Quantitative extracellular volume fraction (ECV) mapping with MRI is commonly used to investigate in vivo diffuse myocardial fibrosis. This study…”
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SCN5A mutation type and topology are associated with the risk of ventricular arrhythmia by sodium channel blockers by Amin, Ahmad S., Reckman, Yolan J., Arbelo, Elena, Spanjaart, Anne M., Postema, Pieter G., Tadros, Rafik, Tanck, Michael W., Van den Berg, Maarten P., Wilde, Arthur A.M., Tan, Hanno L.

“…Ventricular fibrillation in patients with Brugada syndrome (BrS) is often initiated by premature ventricular contractions (PVCs). Presence of SCN5A mutation…”
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Variants in the 3' untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner by AMIN, Ahmad S, GIUDICESSI, John R, MÜLLER, Martina, WIJNEN, Wino J, TAN, Hanno L, BEZZINA, Connie R, CREEMERS, Esther E, WILDE, Arthur A. M, ACKERMAN, Michael J, PINTO, Yigal M, TIJSEN, Anke J, SPANJAART, Anne M, RECKMAN, Yolan J, KLEMENS, Christine A, TANCK, Michael W, KAPPLINGER, Jamie D, HOFMAN, Nynke, SINNER, Moritz F

“…Heterozygous mutations in KCNQ1 cause type 1 long QT syndrome (LQT1), a disease characterized by prolonged heart rate-corrected QT interval (QTc) and…”
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Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy by Bakermans, Adrianus J., Boekholdt, S. Matthijs, Vries, Dylan K., Reckman, Yolan J., Farag, Emile S., Heer, Paul, Uthman, Laween, Denis, Simone W., Zuurbier, Coert J., Houtkooper, Riekelt H., Koolbergen, David R., Kluin, Jolanda, Planken, R. Nils, Lamb, Hildo J., Webb, Andrew G., Strijkers, Gustav J., Beard, Daniel A., Jeneson, Jeroen A.L., Nederveen, Aart J.

“…Background Proton magnetic resonance spectroscopy (1H‐MRS) of the human heart is deemed to be a quantitative method to investigate myocardial metabolite…”
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Yield and Pitfalls of Ajmaline Testing in the Evaluation of Unexplained Cardiac Arrest and Sudden Unexplained Death: Single-Center Experience With 482 Families by Tadros, Rafik, Nannenberg, Eline A, Lieve, Krystien V, Škorić-Milosavljević, Doris, Lahrouchi, Najim, Lekanne Deprez, Ronald H, Vendrik, Jeroen, Reckman, Yolan J, Postema, Pieter G, Amin, Ahmad S, Bezzina, Connie R, Wilde, Arthur A M, Tan, Hanno L

“…This study evaluated the yield of ajmaline testing and assessed the occurrence of confounding responses in a large cohort of families with unexplained cardiac…”
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Yield and Pitfalls of Ajmaline Testing in the Evaluation of Unexplained Cardiac Arrest and Sudden Unexplained Death by Tadros, Rafik, Nannenberg, Eline A., Lieve, Krystien V., Škorić-Milosavljević, Doris, Lahrouchi, Najim, Lekanne Deprez, Ronald H., Vendrik, Jeroen, Reckman, Yolan J., Postema, Pieter G., Amin, Ahmad S., Bezzina, Connie R., Wilde, Arthur A.M., Tan, Hanno L.

“…This study evaluated the yield of ajmaline testing and assessed the occurrence of confounding responses in a large cohort of families with unexplained cardiac…”
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Formins Emerge as a Cause of Hypertrophic Cardiomyopathy by Pinto, Yigal M., Reckman, Yolan J.

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TTN Circular RNAs Create A Backsplice Motif Essential for SRSF10 Splicing by Tijsen, Anke J., Ortega, Lucίa Cόcera, Reckman, Yolan J., Zhang, Xiaolei, van der Made, Ingeborg, Aufiero, Simona, Li, Jiuru, Kamps, Selina C., van den Bout, Anouk, Devalla, Harsha D., van Spaendonck-Zwarts, Karin Y., Engelhardt, Stefan, Gepstein, Lior, Ware, James S., Pinto, Yigal M.

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Abstract 28: In Vivo Knockdown of Mirna-15b Results in Increased Cardiac Hypertrophy and Fibrosis in Response to Pressure Overload of the Mouse Heart by Tijsen, Anke J, van der Made, Ingeborg, van Deel, Elza D, Hiller, Monika, Reckman, Yolan J, Duncker, Dirk J, Pinto, Yigal M, Creemers, Esther E

“…Abstract only MiRNAs play an important role in the control of diverse aspects of cardiac function. MiR-15b is highly expressed in the heart and is found…”
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