Search Results - "Reck, Margaret R"
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β-Lactone formation during product release from a nonribosomal peptide synthetase
Published in Nature chemical biology (01-07-2017)“…In vitro reconstitution of five enzymes elucidates the biosynthetic pathway of obafluorin (Obi) and reveals that ObiF uses an unusual thioesterase domain to…”
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Journal Article -
2
Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes
Published in Nature chemical biology (01-07-2017)“…Structural and functional characterization of tetracycline-inactivating enzymes reveals that inhibitors act by locking the enzyme in an unproductive state by…”
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Journal Article -
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[beta]-Lactone formation during product release from a nonribosomal peptide synthetase
Published in Nature chemical biology (01-07-2017)“…Nonribosomal peptide synthetases (NRPSs) are multidomain modular biosynthetic assembly lines that polymerize amino acids into a myriad of biologically active…”
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Journal Article