Search Results - "Recinos, Adrian"
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An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice
Published in The Journal of clinical investigation (01-12-2009)“…Vascular inflammation contributes to cardiovascular diseases such as aortic aneurysm and dissection. However, the precise inflammatory pathways involved have…”
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Vascular Inflammation and the Renin-Angiotensin System
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2002)“…ABSTRACT—It is now well established that vascular inflammation is an independent risk factor for the development of atherosclerosis. In otherwise healthy…”
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Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodeling
Published in Journal of vascular research (01-01-2011)“…The role of adventitial fibroblasts in the vascular inflammation observed in the adventitia of large vessels in numerous cardiovascular diseases remains…”
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Molecular classification of outcomes from dengue virus -3 infections
Published in Journal of clinical virology (01-03-2015)“…Highlights • We conducted a biomarker study associated with complications of dengue infection. • We apply a novel liquid separations-proteomics profiling to…”
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Interleukin-6–Signal Transducer and Activator of Transcription-3 Signaling Mediates Aortic Dissections Induced by Angiotensin II via the T-Helper Lymphocyte 17–Interleukin 17 Axis in C57BL/6 Mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-07-2013)“…OBJECTIVE—Dysregulated angiotensin II (Ang II) signaling induces local vascular interleukin-6 (IL-6) secretion, producing leukocyte infiltration and…”
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Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice
Published in Atherosclerosis (01-09-2007)“…Abstract Angiotensin II (A-II), the major effector peptide of the renin angiotensin system potently accelerates progression of atherosclerosis. To investigate…”
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Roles of IL-6-gp130 Signaling in Vascular Inflammation
Published in Current cardiology reviews (01-08-2008)“…Interleukin-6 (IL-6) is a well-established, independent indicator of multiple distinct types of cardiovascular disease and all-cause mortality. In this review,…”
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IL‐6 Regulates Extracellular Matrix Remodeling Associated With Aortic Dilation in a Fibrillin‐1 Hypomorphic mgR/mgR Mouse Model of Severe Marfan Syndrome
Published in Journal of the American Heart Association (01-02-2014)“…Background Development of thoracic aortic aneurysms is the most significant clinical phenotype in patients with Marfan syndrome. An inflammatory response has…”
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Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles
Published in BMC developmental biology (23-09-2016)“…Nuclear Factor-Kappa B (NF-kB) is a family of transcription factors that are important in embryonic development, inflammation, epithelial-to-mesenchymal…”
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Discovery Proteomics and Nonparametric Modeling Pipeline in the Development of a Candidate Biomarker Panel for Dengue Hemorrhagic Fever
Published in Clinical and translational science (01-02-2012)“…Secondary dengue viral infection can produce capillary leakage associated with increased mortality known as dengue hemorrhagic fever (DHF). Because the…”
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Liver gene expression associated with diet and lesion development in atherosclerosis-prone mice: induction of components of alternative complement pathway
Published in Physiological genomics (16-09-2004)“…1 Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555-1060 2 Department of Microbiology and Immunology, University of…”
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Abstract 667: The Role of Aortic Wall-Nuclear Factor- kappa B (NF-kB) Signaling in Formation of Dissecting Aortic Aneurysms
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2015)“…Abstract only Introduction: Abdominal aortic aneurysm is a devastating disease since it can lead to aortic rupture and instantaneous death. We previously…”
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RhoA Mediates Angiotensin II–Induced Phospho-Ser536 Nuclear Factor κB/RelA Subunit Exchange on the Interleukin-6 Promoter in VSMCs
Published in Circulation research (29-09-2006)“…The vasoconstrictor angiotensin II (Ang II) accelerates atherosclerosis by inducing vascular gene expression programs, producing monocyte recruitment, and…”
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The atherogenic lipoprotein phenotype is not caused by a mutation in the coding region of the low density lipoprotein receptor gene
Published in Clinical genetics (01-04-1997)“…The atherogenic lipoprotein phenotype (ALP) is a common heritable trait characterized by a predominance of small, dense low density lipoprotein particles…”
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RhoA Mediates Angiotensin II-Induced Phospho-Ser536 Nuclear Factor B/RelA Subunit Exchange on the Interleukin-6 Promoter in VSMCs
Published in Circulation research (01-09-2006)“…The vasoconstrictor angiotensin II (Ang II) accelerates atherosclerosis by inducing vascular gene expression programs, producing monocyte recruitment, and…”
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RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs
Published in Circulation research (29-09-2006)“…The vasoconstrictor angiotensin II (Ang II) accelerates atherosclerosis by inducing vascular gene expression programs, producing monocyte recruitment, and…”
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High-level secretory expression of immunologically active intact antibody from the yeast Pichia pastoris
Published in Biotechnology letters (01-06-1999)“…We have produced a functional murine antibody to dioxin in the culture medium of the methylotrophic yeast Pichia pastoris. Complementary DNA copies encoding…”
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Physical maps of human α(1,3)fucosyltransferase genes FUT3–FUT6 on chromosomes 19p13.3 and 11q21
Published in Genomics (San Diego, Calif.) (01-03-1995)“…Sialyl Lewis x and related fucosylated glycans are differentially expressed in human cells and form ligands for selectin adhesion receptors…”
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