Search Results - "Rechsteiner, Martin C"
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Hsp90 Enhances Degradation of Oxidized Calmodulin by the 20 S Proteasome
Published in The Journal of biological chemistry (29-10-2004)“…The 20 S proteasome has been suggested to play a critical role in mediating the degradation of abnormal proteins under conditions of oxidative stress and has…”
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Out with the old, in with the new? Comparing methods for measuring protein degradation
Published in Cell biology international (01-05-2011)“…Protein degradation is a critical factor in controlling cellular protein abundance. Here, we compare classical methods for determining protein degradation…”
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Intracellular Localization of Proteasomal Degradation of a Viral Antigen
Published in The Journal of cell biology (12-07-1999)“…To better understand proteasomal degradation of nuclear proteins and viral antigens we studied mutated forms of influenza virus nucleoprotein (NP) that misfold…”
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Ubiquitin-mediated proteolysis: an ideal pathway for systems biology analysis
Published in Advances in experimental medicine and biology (2004)“…Ubiquitin is a small, evolutionarily conserved eukaryotic protein that can be attached to a wide variety of intracellular proteins including itself. Covalent…”
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Tertiary structural rearrangements upon oxidation of Methionine145 in calmodulin promotes targeted proteasomal degradation
Published in Biophysical journal (15-08-2006)“…The selectivity underlying the recognition of oxidized calmodulin (CaM) by the 20S proteasome in complex with Hsp90 was identified using mass spectrometry. We…”
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Subcellular localization of proteasomes and their regulatory complexes in mammalian cells
Published in Biochemical journal (15-02-2000)“…Proteasomes can exist in several different molecular forms in mammalian cells. The core 20S proteasome, containing the proteolytic sites, binds regulatory…”
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7
Hsp90 Enhances Degradation of Oxidized Calmodulin by the 20S Proteasome
Published in The Journal of biological chemistry (29-10-2004)“…The 20S proteasome has been suggested to play a critical role in mediating the degradation of abnormal proteins under conditions of oxidative stress, and has…”
Get full text
Journal Article -
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Tertiary Structural Rearrangements upon Oxidation of Methionine 145 in Calmodulin Promotes Targeted Proteasomal Degradation
Published in Biophysical journal (2006)“…The selectivity underlying the recognition of oxidized calmodulin (CaM) by the 20S proteasome in complex with Hsp90 was identified using mass spectrometry. We…”
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Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system
Published in The Journal of experimental medicine (21-07-1997)“…To generate peptides for presentation by major histocompatibility complex (MHC) class I molecules to T lymphocytes, the immune system of vertebrates has…”
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10
Subcellular localization of proteasomes and their regulatory complexes in mammalian cells
Published in Biochemical journal (15-02-2000)“…Proteasomes can exist in several different molecular forms in mammalian cells. The core 20S proteasome, containing the proteolytic sites, binds regulatory…”
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The Human Genome Project: misguided science policy
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-12-1991)“…Genome mapping and sequencing projects are inappropriate and wasteful expenditures of precious research funds. By focusing on the acquisition of nucleotide…”
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Microinjection of thymidine kinase and bovine serum albumin into mammalian cells by fusion with red blood cells
Published in Cell (01-01-1975)“…A procedure is described by which proteins can be rapidly and efficiently microinjected into large numbers of culture cells. Proteins were first introduced…”
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Red cell-mediated microinjection of macromolecules into mammalian cells
Published in Methods in cell biology (1978)Get more information
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Drosophila lactate dehydrogenase: partial purification and characterization
Published in Journal of insect physiology (01-01-1970)Get more information
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