Search Results - "Rebocho, Ana Paula"
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New insight puts CRAF in sight as a therapeutic target
Published in Cancer discovery (01-07-2011)“…By selectively depleting components of the RAF-MEK-ERK pathway in transgenic mice, it is now shown in 2 studies that CRAF is critical for signaling to MEK…”
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Abstract 2340: Disentangling the Myc:Max from the Mad:Max network
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract The Myc family comprises three basic helix loop helix leucine zipper (bHLHLZ) transcription factors - C-myc, N-myc and L-myc - which regulate a…”
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Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines
Published in Thyroid (New York, N.Y.) (01-08-2007)“…Our aim was to characterize the molecular and genotypic profile of eight thyroid carcinoma-derived cell lines-TPC1, FB2, B-CPAP, K1, XTC-1, C643, 8505C, and…”
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BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas
Published in Virchows Archiv : an international journal of pathology (01-06-2004)“…Somatic mutations of the BRAF gene (BRAFV599E and BRAFK600E) were found to be closely associated with different histotypes of papillary thyroid carcinoma…”
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A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation
Published in Virchows Archiv : an international journal of pathology (01-06-2007)“…c-KIT is a tyrosine kinase receptor found to be overexpressed in several tumours, namely, GISTs, breast, lung, prostate, ovarian and colorectal carcinomas…”
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