Search Results - "Rebessi, Simonetta"

Oncogenic bystander radiation effects in Patched heterozygous mouse cerebellum by Mancuso, Mariateresa, Pasquali, Emanuela, Leonardi, Simona, Tanori, Mirella, Rebessi, Simonetta, Di Majo, Vincenzo, Pazzaglia, Simonetta, Toni, Maria Pia, Pimpinella, Maria, Covelli, Vincenzo, Saran, Anna

“…The central dogma of radiation biology, that biological effects of ionizing radiation are a direct consequence of DNA damage occurring in irradiated cells, has…”
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Physical, Heritable and Age-Related Factors as Modifiers of Radiation Cancer Risk in Patched Heterozygous Mice by Pazzaglia, Simonetta, Ph.D, Pasquali, Emanuela, M.Sc, Tanori, Mirella, Ph.D, Mancuso, Mariateresa, Ph.D, Leonardi, Simona, Ph.D, di Majo, Vincenzo, Ph.D, Rebessi, Simonetta, Ph.D, Saran, Anna, Ph.D

“…Purpose To address the tumorigenic potential of exposure to low/intermediate doses of ionizing radiation and to identify biological factors influencing tumor…”
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High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice by Pazzaglia, Simonetta, Mancuso, Mariateresa, Atkinson, Michael J, Tanori, Mirella, Rebessi, Simonetta, Majo, Vincenzo Di, Covelli, Vincenzo, Hahn, Heidi, Saran, Anna

“…Individuals affected with the Gorlin syndrome inherit a germ-line mutation of the patched (Ptc1) developmental gene and, analogously to Ptc1 heterozygous mice,…”
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Developmental and oncogenic effects of insulin-like growth factor-I in Ptc1+/- mouse cerebellum by Tanori, Mirella, Santone, Melissa, Mancuso, Mariateresa, Pasquali, Emanuela, Leonardi, Simona, Di Majo, Vincenzo, Rebessi, Simonetta, Saran, Anna, Pazzaglia, Simonetta

“…Medulloblastoma is amongst the most common malignant brain tumors in childhood, arising from neoplastic transformation of granule neuron precursors (GNPs) of…”
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Modulation of Patched-associated susceptibility to radiation induced tumorigenesis by genetic background by PAZZAGLIA, Simonetta, MANCUSO, Mariateresa, TANORI, Mirella, ATKINSON, Michael J, MEROLA, Paola, REBESSI, Simonetta, DI MAJO, Vincenzo, COVELLI, Vincenzo, HAHN, Heidi, SARAN, Anna

“…We described previously a basal cell carcinoma (BCC) and medulloblastoma (MB) phenotype for CD1Ptch1(neo67/+) mice exposed to ionizing radiation. Ptch1…”
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A cancer modifier role for parathyroid hormone-related protein by MANENTI, Giacomo, PEISSEL, Bernard, DRAGANI, Tommaso A, GARIBOLDI, Manuela, FALVELLA, F. Stefania, ZAFFARONI, Daniela, ALLARIA, Biagino, PAZZAGLIA, Simonetta, REBESSI, Simonetta, COVELLI, Vincenzo, SARAN, Anna

“…The parathyroid hormone-related protein (PTHrP) gene (Pthlh) maps in the distal region of mouse chromosome 6 that contains a quantitative trait locus…”
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Hair cycle-dependent basal cell carcinoma tumorigenesis in Ptc1neo67/+ mice exposed to radiation by Mancuso, Mariateresa, Leonardi, Simona, Tanori, Mirella, Pasquali, Emanuela, Pierdomenico, Maria, Rebessi, Simonetta, Di Majo, Vincenzo, Covelli, Vincenzo, Pazzaglia, Simonetta, Saran, Anna

“…We examined the effects of hair cycle phase on basal cell carcinoma (BCC) tumorigenesis induced by radiation in mice lacking one Patched allele…”
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Basal Cell Carcinoma and Its Development by Mancuso, Mariateresa, Pazzaglia, Simonetta, Tanori, Mirella, Hahn, Heidi, Merola, Paola, Rebessi, Simonetta, Atkinson, Michael J., Di Majo, Vincenzo, Covelli, Vincenzo, Saran, Anna

“…Loss-of-function mutations in Patched (Ptch1) are implicated in constitutive activation of the Sonic hedgehog pathway in human basal cell carcinomas (BCCs),…”
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The Influence of Sex on Life Shortening and Tumor Induction in CBA/Cne Mice Exposed to X Rays or Fission Neutrons by Di Majo, Vincenzo, Coppola, Mario, Rebessi, Simonetta, Saran, Anna, Pazzaglia, Simonetta, Pariset, Lorraine, Covelli, Vincenzo

“…An experimental study of male and female CBA/Cne mice was set up at Casaccia primarily to investigate the influence of sex on long-term survival and tumor…”
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Basal cell carcinoma and its development: Insights from radiation-induced tumors in Ptch1-deficient mice by MANCUSO, Mariateresa, PAZZAGLIA, Simonetta, TANORI, Mirella, HAHN, Heidi, MEROLA, Paola, REBESSI, Simonetta, ATKINSON, Michael J, DI MAJO, Vincenzo, COVELLI, Vincenzo, SARAN, Anna

“…Loss-of-function mutations in Patched (Ptch1) are implicated in constitutive activation of the Sonic hedgehog pathway in human basal cell carcinomas (BCCs),…”
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Protective role of 17β‐estradiol on medulloblastoma development in Patched1 heterozygous mice by Mancuso, Mariateresa, Leonardi, Simona, Ceccarelli, Manuela, Pasquali, Emanuela, Stefano, Ilaria De, Prisco, Maria Grazia, Rebessi, Simonetta, Tanori, Mirella, Scambia, Giovanni, Majo, Vincenzo Di, Pazzaglia, Simonetta, Saran, Anna, Gallo, Daniela

“…Medulloblastoma (MB) is the most common pediatric tumor of the CNS, representing ∼20% of all childhood CNS tumors. Although in recent years many molecular…”
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PARP-1 cooperates with Ptc1 to suppress medulloblastoma and basal cell carcinoma by Tanori, Mirella, Mancuso, Mariateresa, Pasquali, Emanuela, Leonardi, Simona, Rebessi, Simonetta, Di Majo, Vincenzo, Guilly, Marie-Noëlle, Giangaspero, Felice, Covelli, Vincenzo, Pazzaglia, Simonetta, Saran, Anna

“…The patched (Ptc1) protein is a negative regulator of sonic hedgehog signaling, a genetic pathway whose perturbation causes developmental defects and…”
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Protective role of 17 Delta b-estradiol on medulloblastoma development in Patched1 heterozygous mice by Mancuso, Mariateresa, Leonardi, Simona, Ceccarelli, Manuela, Pasquali, Emanuela, De Stefano, Ilaria, Prisco, Maria Grazia, Rebessi, Simonetta, Tanori, Mirella, Scambia, Giovanni, Di Majo, Vincenzo, Pazzaglia, Simonetta, Saran, Anna, Gallo, Daniela

“…Medulloblastoma (MB) is the most common pediatric tumor of the CNS, representing ~20% of all childhood CNS tumors. Although in recent years many molecular…”
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Developmental and oncogenic effects of Insulin-like Growth Factor-I in Ptc1.sup.+/- .sup.mouse cerebellum by Tanori, Mirella, Santone, Melissa, Mancuso, Mariateresa, Pasquali, Emanuela, Leonardi, Simona, Di Majo, Vincenzo, Rebessi, Simonetta, Saran, Anna, Pazzaglia, Simonetta

“…Background Medulloblastoma is amongst the most common malignant brain tumors in childhood, arising from neoplastic transformation of granule neuron precursors…”
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Protective role of 17β-estradiol on medulloblastoma development in Patchedl heterozygous mice by MANCUSO, Mariateresa, LEONARDI, Simona, PAZZAGLIA, Simonetta, SARAN, Anna, GALLO, Daniela, CECCARELLI, Manuela, PASQUALI, Emanuela, DE STEFANO, Ilaria, GRAZIA PRISCO, Maria, REBESSI, Simonetta, TANORI, Mirella, SCAMBIA, Giovanni, DI MAJO, Vincenzo

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Genetic events associated with arsenic-induced malignant transformation: applications of cDNA microarray technology by Chen, Hua, Liu, Jie, Merrick, Bruce A., Waalkes, Michael P.

“…Arsenic is a human carcinogen. Our recent work showed that chronic (>18 wk), low‐level (125–500 nM) arsenite exposure induces malignant transformation in…”
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Hair Cycle-Dependent Basal Cell Carcinoma Tumorigenesis in Ptc1 super(neo67/+) Mice Exposed to Radiation by Mancuso, Mariateresa, Leonardi, Simona, Tanori, Mirella, Pasquali, Emanuela, Pierdomenico, Maria, Rebessi, Simonetta, Di Majo, Vincenzo, Covelli, Vincenzo, Pazzaglia, Simonetta, Saran, Anna

“…We examined the effects of hair cycle phase on basal cell carcinoma (BCC) tumorigenesis induced by radiation in mice lacking one Patched allele (Ptc1…”
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Carcinogenesis in Laboratory Mice after Low Doses of Ionizing Radiation by Di Majo, Vincenzo, Rebessi, Simonetta, Pazzaglia, Simonetta, Saran, Anna, Covelli, Vincenzo

“…Di Majo, V., Rebessi, S., Pazzaglia, S., Saran, A. and Covelli, V. Carcinogenesis in Laboratory Mice after Low Doses of Ionizing Radiation. Radiat. Res. 159,…”
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Protective role of 17 β-estradiol on medulloblastoma development in Patched 1 heterozygous mice by Mancuso, Mariateresa, Leonardi, Simona, Ceccarelli, Manuela, Pasquali, Emanuela, De Stefano, Ilaria, Prisco, Maria Grazia, Rebessi, Simonetta, Tanori, Mirella, Scambia, Giovanni, Di Majo, Vincenzo, Pazzaglia, Simonetta, Saran, Anna, Gallo, Daniela

“…Medulloblastoma (MB) is the most common pediatric tumor of the CNS, representing ∼20% of all childhood CNS tumors. Although in recent years many molecular…”
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High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1heterozygous mice by Pazzaglia, Simonetta, Mancuso, Mariateresa, Atkinson, Michael J, Tanori, Mirella, Rebessi, Simonetta, Majo, Vincenzo Di, Covelli, Vincenzo, Hahn, Heidi, Saran, Anna

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