Search Results - "Rebek Jr, Julius"

Hydroxy Oximes as Organophosphorus Nerve Agent Sensors by Dale, Trevor J, Rebek, Julius Jr

“…Find and destroy: A series of oximes were constructed to simultaneously detect and detoxify organophosphorus‐based nerve agents. They function as optical…”
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Stabilization of Labile Carbonyl Addition Intermediates by a Synthetic Receptor by Iwasawa, Tetsuo, Hooley, Richard J, Rebek, Julius Jr

“…Products of unfavorable chemical equilibria are not readily observed because their high energy and increased reactivity result in low concentrations…”
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Photochemical Control of Reversible Encapsulation by Dube, Henry, Ajami, Dariush, Rebek, Julius Jr

“…Remote control: Molecules can be transferred in a chemical system between capsules and bulk solution by using light and heat. The principle is based on the…”
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Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus by Prieto, G. Aleph, Snigdha, Shikha, Baglietto-Vargas, David, Smith, Erica D., Berchtold, Nicole C., Tong, Liqi, Ajami, Dariush, LaFerla, Frank M., Rebek, Julius, Cotman, Carl W.

“…In the aged brain, synaptic plasticity and memory show increased vulnerability to impairment by the inflammatory cytokine interleukin 1β (IL-1β). In this…”
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Ouroborand: A Cavitand with a Coordination-Driven Switching Device by Durola, Fabien, Rebek, Julius Jr

“…Molecular switch: The ouroborand coordinates an internal side chain in its cavity, just as it were swallowing its own tail. The presence or absence of zinc(II)…”
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Molecular Encapsulation by Hof, Fraser, Craig, Stephen L., Nuckolls, Colin, Rebek, Jr, Julius

“…Louis Kahn, architect of the Salk Institute in La Jolla, said1 “even a common, ordinary brick wants to be something more than it is.” Suppose that were also…”
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Helical Conformation of Alkanes in a Hydrophobic Cavitand by Trembleau, Laurent, Rebek, Julius

“…Alkanes adopt extended conformations in solution that minimize steric interactions and maximize surface area. Folding can reduce the amount of hydrophobic…”
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Gas Behavior in Self-Assembled Capsules by Ajami, Dariush, Rebek, Julius Jr

“…Gas encapsulation: Several cyclopropane or butane molecules are reversibly bound in self‐assembled, hydrogen‐bonded capsules under ambient conditions (see…”
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Specific Binding of a β-Cyclodextrin Dimer to the Amyloid β Peptide Modulates the Peptide Aggregation Process by Wahlström, Anna, Cukalevski, Risto, Danielsson, Jens, Jarvet, Jüri, Onagi, Hideki, Rebek, Julius, Linse, Sara, Gräslund, Astrid

“…Alzheimer’s disease involves progressive neuronal loss. Linked to the disease is the amyloid β (Aβ) peptide, a 38–43-amino acid peptide found in extracellular…”
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Autocatalysis and organocatalysis with synthetic structures by Kamioka, Seiji, Ajami, Dariush, Rebek, Julius Jr

“…The discovery of ribozymes led to the proposal of an RNA world, where a single type of molecule was supposedly capable of self-replication and chemical…”
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Adaptations of guest and host in expanded self-assembled capsules by Ajami, Dariush, Rebek, Julius Jr

“…Reversible encapsulation complexes create spaces where two or more molecules can be temporarily isolated. When the mobility of encapsulated molecules is…”
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Supramolecular Architecture with a Cavitand-Capsule Chimera by Lledó, Agustí, Kamioka, Seiji, Sather, Aaron C, Rebek, Julius Jr

“…Molecule‐within‐molecule complexes are widely used in supramolecular chemistry for studies of molecular recognition and catalysis. Self‐assembled hosts isolate…”
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Cavitand templated catalysis of acetylcholine by Zelder, Felix H, Rebek, Jr, Julius

“…A Zn-salen-modified cavitand templates the catalytic formation of acetylcholine from choline and acetic anhydride…”
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MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics by Christopher N. Davis, Enrique Mann, M. Margarita Behrens, Svetlana Gaidarova, Mitra Rebek, Julius Rebek, Jr, Tamas Bartfai

“…Interleukin (IL)-1β is a pluripotent proinflammatory cytokine that signals through the type-I IL-1 receptor (IL-1RI), a member of the Toll-like receptor…”
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Modeling Amine Methylation in Methyl Ester Cavitand by Norjmaa, Gantulga, Rebek, Julius, Himo, Fahmi

“…Methylation of amines inside an introverted resorcinarene‐based deep methyl ester cavitand is investigated by means of molecular dynamics simulations and…”
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Synthetic autocatalysts show organocatalysis of other reactions by Kamioka, Seiji, Ajami, Dariush, Rebek, Jr, Julius

“…A molecule capable of both autocatalysis and organocatalysis was synthesized. The autocatalytic activity results from the self-complementary recognition sites…”
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Selective Guest Exchange in Encapsulation Complexes Using Light of Different Wavelenghts by Dube, Henry, Rebek Jr, Julius

“…A matter of light: Selective control over the assembly of two distinct encapsulation complexes in solution is achieved by using light of two wavelengths and…”
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Simultaneous Encapsulation: Molecules Held at Close Range by Rebek Jr, Julius

“…Reversible encapsulation creates spaces where molecules are temporarily isolated from others in solution. Molecules are held within the space of the capsule…”
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Chemical approaches for detection and destruction of nerve agents by Ajami, Dariush, Rebek, Jr, Julius

“…Since the introduction of organophosphorus (OP) compounds as nerve agents and pesticides, methods of dealing with their toxicity to humans have been intensely…”
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Selective Binding and Isomerization of Oximes in a Self-Assembled Capsule by Kanagaraj, Kuppusamy, Wang, Rui, Zhao, Ming-Kai, Ballester, Pablo, Rebek, Julius, Yu, Yang

“…A series of straight-chain (C7–C13) alkyl-O-methyl aldoximes (R–C­(H)NOMe) were synthesized with various functional groups at the remote ends (alkenes,…”
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