Search Results - "Reaves, J."
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Multiplexed ddPCR-amplicon sequencing reveals isolated Plasmodium falciparum populations amenable to local elimination in Zanzibar, Tanzania
Published in Nature communications (22-06-2023)“…Zanzibar has made significant progress toward malaria elimination, but recent stagnation requires novel approaches. We developed a highly multiplexed droplet…”
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Women attending antenatal care as a sentinel surveillance population for malaria in Geita region, Tanzania: feasibility and acceptability to women and providers
Published in Malaria journal (24-02-2023)“…Measurement of malaria prevalence is conventionally estimated through infrequent cross-sectional household surveys that do not provide continuous information…”
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3
Trends of insecticide resistance monitoring in mainland Tanzania, 2004-2020
Published in Malaria journal (17-03-2023)“…Insecticide resistance is a serious threat to the continued effectiveness of insecticide-based malaria vector control measures, such as long-lasting…”
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4
Lack of detectable short-term effects of a single dose of ivermectin on the human immune system
Published in Parasites & vectors (05-06-2021)“…Ivermectin is widely used in human and animal medicine to treat and prevent parasite nematode infections. It has been suggested that its mode of action…”
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Similar Prevalence of Plasmodium falciparum and Non-P. falciparum Malaria Infections among Schoolchildren, Tanzania
Published in Emerging infectious diseases (01-06-2023)“…Achieving malaria elimination requires considering both Plasmodium falciparum and non–P. falciparum infections. We determined prevalence and geographic…”
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Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probes
Published in Molecular ecology (01-01-2021)“…High‐throughput Plasmodium genomic data is increasingly useful in assessing prevalence of clinically important mutations and malaria transmission patterns…”
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Evaluation of a single screen and treat strategy to detect asymptomatic malaria among pregnant women from selected health facilities in Lindi region, Tanzania
Published in Malaria journal (30-11-2020)“…In areas of high transmission, malaria in pregnancy (MiP) primarily causes asymptomatic infections; these infections nonetheless increase the risk of adverse…”
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Acceptability of single screening and treatment policy for the control of malaria in pregnancy: perceptions of providers and pregnant women from selected health facilities in Lindi region, Tanzania
Published in Malaria journal (08-06-2021)“…Background Tanzania started implementing single screening and treatment (SST) for all pregnant women attending their first antenatal care (ANC) visits in 2014,…”
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EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor
Published in PLoS pathogens (01-04-2020)“…Nematode parasites infect approximately 1.5 billion people globally and are a significant public health concern. There is an accepted need for new, more…”
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10
Estimating malaria burden among pregnant women using data from antenatal care centres in Tanzania: a population-based study
Published in The Lancet global health (01-12-2019)“…More timely estimates of malaria prevalence are needed to inform optimal control strategies and measure progress. Since 2014, Tanzania has implemented…”
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Evidence of sustained reductions in the relative risk of acute hepatitis B and C virus infections, and the increasing burden of hepatitis a virus infection in Egypt: comparison of sentinel acute viral hepatitis surveillance results, 2001-17
Published in BMC infectious diseases (14-02-2019)“…Egypt ranks fifth for the burden of viral hepatitis worldwide. As part of Egypt's renewed national strategy for the elimination of viral hepatitis,…”
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12
Human Leukocytes Kill Brugia malayi Microfilariae Independently of DNA-Based Extracellular Trap Release
Published in PLoS neglected tropical diseases (03-01-2017)“…Wuchereria bancrofti, Brugia malayi and Brugia timori infect over 100 million people worldwide and are the causative agents of lymphatic filariasis. Some…”
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13
LegC3, an effector protein from Legionella pneumophila, inhibits homotypic yeast vacuole fusion in vivo and in vitro
Published in PloS one (20-02-2013)“…During infection, the intracellular pathogenic bacterium Legionella pneumophila causes an extensive remodeling of host membrane trafficking pathways, both in…”
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Improvements in malaria surveillance through the electronic Integrated Disease Surveillance and Response (eIDSR) system in mainland Tanzania, 2013-2021
Published in Malaria journal (08-11-2022)“…Tanzania has made remarkable progress in reducing malaria burden and aims to transition from malaria control to sub-national elimination. In 2013, electronic…”
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Risk factors associated with malaria infection identified through reactive case detection in Zanzibar, 2012-2019
Published in Malaria journal (24-12-2021)“…Over the past two decades, Zanzibar substantially reduced malaria burden. As malaria decreases, sustainable improvements in control interventions may…”
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Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite
Published in International journal for parasitology -- drugs and drug resistance (01-08-2019)“…The macrocyclic lactone anthelmintics are the only class of drug currently used to prevent heartworm disease. Their extremely high potency in vivo is not…”
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Diarrhea outbreak during U.S. military training in El Salvador
Published in PloS one (18-07-2012)“…Infectious diarrhea remains a major risk to deployed military units worldwide in addition to their impact on travelers and populations living in the developing…”
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Identification of Mammalian Vps24p as an Effector of Phosphatidylinositol 3,5-Bisphosphate-dependent Endosome Compartmentalization
Published in The Journal of biological chemistry (03-10-2003)“…Phosphatidylinositol 3,5-bisphosphate is a membrane lipid found in all eukaryotes so far studied but downstream effector proteins of this lipid have yet to be…”
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The quality of malaria case management in different transmission settings in Tanzania mainland, 2017–2018
Published in PLOS global public health (21-08-2023)“…Tanzania is undergoing an epidemiological transition for malaria transmission with some areas of the country having <10% (hypoendemic) and other areas 10% -…”
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The role of lipid raft aggregation in the infection of type II pneumocytes by Mycobacterium tuberculosis
Published in PloS one (14-09-2012)“…Dynamic, cholesterol-dense regions of the plasma membrane, known as lipid rafts (LR), have been observed to develop during and may be directly involved in…”
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