Search Results - "Reardon, C. A."

HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders by Getz, G S, Wool, G D, Reardon, C A

“…Elevations of HDL levels or modifying the inflammatory properties of HDL are being evaluated as possible treatment of atherosclerosis, the underlying mechanism…”
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Nascent Astrocyte Particles Differ from Lipoproteins in CSF by LaDu, M. J., Gilligan, S. M., Lukens, J. R., Cabana, V. G., Reardon, C. A., Van Eldik, L. J., Holtzman, D. M.

“…: Little is known about lipid transport and metabolism in the brain. As a further step toward understanding the origin and function of CNS lipoproteins, we…”
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Isoform-specific binding of apolipoprotein E to beta-amyloid by LaDu, M J, Falduto, M T, Manelli, A M, Reardon, C A, Getz, G S, Frail, D E

“…Apolipoprotein E (apoE), particularly the e4 allele, is genetically linked to the incidence of Alzheimer's disease. ApoE is present in the extracellular senile…”
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Natural killer T cells in lipoprotein metabolism and atherosclerosis by Getz, G S, Vanderlaan, P A, Reardon, C A

“…Cells of both the innate and adaptive immune system participate in the development of atherosclerosis, a chronic inflammatory disorder of medium and large…”
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SDS-Stable Complex Formation between Native Apolipoprotein E3 and β-Amyloid Peptides by Munson, Gregory W, Roher, Alex E, Kuo, Yu-Min, Gilligan, Sean M, Reardon, Catherine A, Getz, Godfrey S, LaDu, Mary Jo

“…Extracellular senile plaques composed predominantly of fibrillar amyloid-β (Aβ) are a major neuropathological feature of Alzheimer's disease (AD). Genetic…”
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Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene by Lauer, S J, Walker, D, Elshourbagy, N A, Reardon, C A, Levy-Wilson, B, Taylor, J M

“…The gene for human apolipoprotein (apo) C-I was selected from human genomic cosmid and lambda libraries. Restriction endonuclease analysis showed that the gene…”
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Site Specificity of Atherosclerosis: Site-Selective Responses to Atherosclerotic Modulators by VanderLaan, Paul A, Reardon, Catherine A, Getz, Godfrey S

“…ABSTRACT—Atherosclerosis is a complex disease process that affects very specific sites of the vasculature. It is recognized that hemodynamic forces are largely…”
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Diet and Murine Atherosclerosis by Getz, Godfrey S, Reardon, Catherine A

“…Lipid-enriched diets are often used to induce or accelerate the rate of atherosclerotic lesion development in murine models of atherosclerosis. It appears that…”
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Nucleotide Sequence and Structure of the Human Apolipoprotein E Gene by Paik, Young-Ki, Chang, David J., Reardon, Catherine A., Davies, Glenn E., Mahley, Robert W., Taylor, John M.

“…The gene for human apolipoprotein E (apo-E) was selected from a library of cloned genomic DNA by screening with a specific cDNA hybridization probe, and its…”
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In Vivo Studies of HDL Assembly and Metabolism Using Adenovirus-Mediated Transfer of ApoA-I Mutants in ApoA-I-Deficient Mice by Reardon, Catherine A, Kan, Horng-Yuan, Cabana, Veneracion, Blachowicz, Lydia, Lukens, John R, Wu, Qingzhou, Liadaki, Kalliopi, Getz, Godfrey S, Zannis, Vassilis I

“…We have used adenovirus-mediated gene transfer in apoA-I-deficient (A-I-/-) mice to probe the in vivo assembly and metabolism of HDL using apoA-I variants,…”
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The influence of acute phase proteins on murine atherosclerosis by Wool, G D, Reardon, C A

“…Atherosclerosis is a chronic inflammatory reaction that is initiated in response to hyperlipidemia and the retention and modification of lipids within the…”
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Frequency thresholds in the energy transmission across Kapitza interfaces by REARDON, A. C

“…When heat is conducted from a solid into liquid helium, a thermal boundary resistance occurs across the interface. This effect, known as Kapitza resistance,…”
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Effect of Immune Deficiency on Lipoproteins and Atherosclerosis in Male Apolipoprotein E-Deficient Mice by Reardon, Catherine A, Blachowicz, Lydia, White, Traci, Cabana, Veneracion, Wang, Yougen, Lukens, John, Bluestone, Jeffrey, Getz, Godfrey S

“…ABSTRACT—To determine whether T cells and B cells influence lipid metabolism and atherosclerosis, we crossed apolipoprotein E-deficient (apoE°) mice with…”
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Identification and characterization of transcriptional regulatory regions associated with expression of the human apolipoprotein E gene by Paik, Y K, Chang, D J, Reardon, C A, Walker, M D, Taxman, E, Taylor, J M

“…Multiple cis-acting regulatory elements have been mapped within a 1-kilobase fragment spanning nucleotides -651 through +356 of the human apolipoprotein E gene…”
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Post-translational regulation of macrophage apoprotein E production by Mazzone, T, Pustelnikas, L, Reardon, C A

“…We have transfected the murine macrophage cell line, J774, which does not express its endogenous apoE gene, with a constitutively expressed human apoE cDNA in…”
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Unique Lipoproteins Secreted by Primary Astrocytes From Wild Type, apoE (−/−), and Human apoE Transgenic Mice by Fagan, Anne M., Holtzman, David M., Munson, Gregory, Mathur, Tanya, Schneider, Danielle, Chang, Louis K., Getz, Godfrey S., Reardon, Catherine A., Lukens, John, Shah, Javeed A., LaDu, Mary Jo

“…Composition of central nervous system lipoproteins affects the metabolism of lipoprotein constituents within the brain. The ε4 allele of apolipoprotein E…”
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Influence of dietary lipids on hepatic mRNA levels of proteins regulating plasma lipoproteins in baboons with high and low levels of large high density lipoproteins by Kushwaha, RS, McMahan, CA, Mott, GE, Carey, KD, Reardon, CA, Getz, GS, McGill, HC

“…Selective breeding of baboons has produced families with increased plasma levels of large high density lipoproteins (HDL1) and very low (VLDL) and low (LDL)…”
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Fracture surface interference effects in mode III by Reardon, A.C., Quesnel, D.J.

“…In this experimental investigation, the effects of fracture surface interference upon the torsional properties of steel alloys were quantitatively…”
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Mouse models of atherosclerosis by Reardon, C A, Getz, G S

“…Atherosclerosis bears many features of a chronic inflammation that affects the intima of large and medium-sized arteries. In recent years apolipoprotein…”
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Human plasma lipoproteins regulate apolipoprotein E secretion from a post-Golgi compartment by Ye, S.Q., Olson, L.M., Reardon, C.A., Getz, G.S.

“…The molecular regulation of apolipoprotein E (apoE) synthesis and secretion is incompletely understood. In this study, we have examined the effect of human low…”
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