Search Results - "Reaman, Gregory H."
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Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (10-05-2012)“…To examine population-based improvements in survival and the impact of clinical covariates on outcome among children and adolescents with acute lymphoblastic…”
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Declining childhood and adolescent cancer mortality
Published in Cancer (15-08-2014)“…BACKGROUND To evaluate whether progress continues in identifying more effective treatments for children and adolescents with cancer, the authors examined both…”
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American Society of Clinical Oncology Statement: Achieving High-Quality Cancer Survivorship Care
Published in Journal of clinical oncology (10-02-2013)Get full text
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Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century
Published in Journal of clinical oncology (20-05-2010)“…This report provides an overview of current childhood cancer statistics to facilitate analysis of the impact of past research discoveries on outcome and…”
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Sustaining innovation and improvement in the treatment of childhood cancer: lessons from high-income countries
Published in The lancet oncology (01-03-2013)“…Summary Cancer in children and adolescents is rare and biologically very different from cancer in adults. It accounts for 1·4% of all cancers worldwide,…”
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JAK mutations in high-risk childhood acute lymphoblastic leukemia
Published in Proceedings of the National Academy of Sciences - PNAS (09-06-2009)“…Pediatric acute lymphoblastic leukemia (ALL) is a heterogeneous disease consisting of distinct clinical and biological subtypes that are characterized by…”
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ARID5B Genetic Polymorphisms Contribute to Racial Disparities in the Incidence and Treatment Outcome of Childhood Acute Lymphoblastic Leukemia
Published in Journal of clinical oncology (01-03-2012)“…Recent genome-wide screens have identified genetic variations in ARID5B associated with susceptibility to childhood acute lymphoblastic leukemia (ALL). We…”
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Remaining Challenges in Childhood Cancer and Newer Targeted Therapeutics
Published in The Pediatric clinics of North America (01-02-2015)“…Despite the enormously important and gratifying advances in cancer treatment outcomes for children with cancer, cancer remains the biggest cause of death from…”
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KMT2A partner genes in infant acute lymphoblastic leukemia have prognostic significance and correlate with age, white blood cell count, sex, and central nervous system involvement: a Children's Oncology Group P9407 trial study
Published in Haematologica (Roma) (01-10-2023)Get full text
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Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia
Published in Blood (18-02-2010)“…To determine whether gene expression profiling could improve outcome prediction in children with acute lymphoblastic leukemia (ALL) at high risk for relapse,…”
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Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study
Published in Blood (23-02-2012)“…Gene expression profiling was performed on 97 cases of infant ALL from Children's Oncology Group Trial P9407. Statistical modeling of an outcome predictor…”
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Phase I Study of ch14.18 With Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-2 in Children With Neuroblastoma After Autologous Bone Marrow Transplantation or Stem-Cell Rescue: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (01-01-2009)“…Recurrence of high-risk neuroblastoma is common despite multimodality therapy. ch14.18, a chimeric human/murine anti-G(D2) antibody, lyses neuroblastoma cells…”
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Phase I Trial of Oral Fenretinide in Children With High-Risk Solid Tumors: A Report From the Children's Oncology Group (CCG 09709)
Published in Journal of clinical oncology (20-07-2006)“…To determine the maximal tolerated dosage (MTD) of oral fenretinide given as intact capsules for 7 days, repeated every 21 days, in children with high-risk…”
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Intensified chemotherapy without SCT in infant ALL: Results from COG P9407 (Cohort 3)
Published in Pediatric blood & cancer (01-03-2015)“…Background Infants with acute lymphoblastic leukemia (ALL) present with aggressive disease and a poor prognosis. Early relapse within 6–9 months of diagnosis…”
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Analysis of the Role of Hematopoietic Stem-Cell Transplantation in Infants With Acute Lymphoblastic Leukemia in First Remission and MLL Gene Rearrangements: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (10-01-2011)“…Although the majority of children with acute lymphoblastic leukemia (ALL) are cured with current therapy, the event-free survival (EFS) of infants with ALL,…”
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Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia
Published in Blood (04-04-2013)“…Survival in infants younger than 1 year who have acute lymphoblastic leukemia (ALL) is inferior whether MLL is rearranged (R) or germline (G). MLL…”
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Maternal Diet and Infant Leukemia: The DNA Topoisomerase II Inhibitor Hypothesis: A Report from the Children's Oncology Group
Published in Cancer epidemiology, biomarkers & prevention (01-03-2005)“…Background: The MLL 11q23 translocation arises in utero and is present in 75% of infant leukemias. That MLL+ acute myeloid leukemia (AML) can arise following…”
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Recombinant Urate Oxidase for the Prophylaxis or Treatment of Hyperuricemia in Patients With Leukemia or Lymphoma
Published in Journal of clinical oncology (01-02-2001)“…To improve the control of hyperuricemia in patients with leukemia or lymphoma, we tested a newly developed uricolytic agent, recombinant urate oxidase…”
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Fine‐Tuning the Relevance of Molecular Targets to Pediatric Cancer: Addressing Additional Layers of Complexity
Published in Clinical pharmacology and therapeutics (01-05-2023)“…The Research to Accelerate Cures and Equity (RACE) for Children Act requires an assessment of molecular targets relevant to pediatric cancer. Due to the…”
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Clinical Cancer Advances 2006: Major Research Advances in Cancer Treatment, Prevention, and Screening—A Report From the American Society of Clinical Oncology
Published in Journal of clinical oncology (01-01-2007)“…A MESSAGE FROM ASCO's PRESIDENT For the second consecutive year, the American Society of Clinical Oncology (ASCO) is publishing Clinical Cancer Advances: Major…”
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